Reactome | ER alpha36 [cytosol]

ER alpha36 [cytosol]

Stable Identifier

R-HSA-9020981

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ESR1(36), Estrogen receptor, ESR1_HUMAN, ER36

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Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
  - PI3K/AKT Signaling in Cancer (Homo sapiens)
    - Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
      - PI3K inhibitors block PI3K catalytic activity (Homo sapiens)
        
        PI3K Inhibitors:PI3K [cytosol] (Homo sapiens)
        
        PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
        
        Activator:PI3K [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG [cytosol] (Homo sapiens)
        
        ESRs [cytosol] (Homo sapiens)
        
        ER alpha36 [cytosol] (Homo sapiens)
        
        PI3K mutants,Activator:PI3K [plasma membrane] (Homo sapiens)
        
        Activator:PI3K [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane] (Homo sapiens)
        
        ESRs:STRN:ESTG [cytosol] (Homo sapiens)
        
        ESRs [cytosol] (Homo sapiens)
        
        ER alpha36 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P03372-4 ESR1

Gene Names

ESR1, ESR, NR3A1

Other Identifiers

0000360020

0104540528

11721785_a_at

11721786_a_at

11736904_a_at

11750485_a_at

11756042_x_at

1298_at

1681_at

17013809

1893_s_at

205225_at

2099

211233_x_at

211234_x_at

211235_s_at

215552_s_at

217163_at

217190_x_at

2931764

2931765

2931774

2931775

2931776

2931779

2931780

2931781

2931782

2931783

2931784

2931785

2931798

2931799

2931812

2931821

2931839

2931840

2931850

2931859

2931860

2931861

2931862

2931863

33670_at

8122840

8122843

A_14_P136162

A_23_P309739

A_24_P325215

A_24_P383478

A_33_P3379356

GE59651

GO:0000003

GO:0000122

GO:0000785

GO:0000978

GO:0000981

GO:0001093

GO:0001223

GO:0001226

GO:0001228

GO:0001547

GO:0002064

GO:0003674

GO:0003677

GO:0003682

GO:0003700

GO:0003707

GO:0004879

GO:0005496

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005794

GO:0005829

GO:0005886

GO:0006338

GO:0006355

GO:0006357

GO:0006367

GO:0006464

GO:0006629

GO:0006950

GO:0007165

GO:0007200

GO:0007204

GO:0007267

GO:0008013

GO:0008134

GO:0008150

GO:0008209

GO:0008219

GO:0008270

GO:0008283

GO:0008289

GO:0008584

GO:0009058

GO:0010629

GO:0010863

GO:0016020

GO:0016021

GO:0016579

GO:0017025

GO:0019899

GO:0019901

GO:0022607

GO:0030111

GO:0030154

GO:0030234

GO:0030235

GO:0030284

GO:0030331

GO:0030518

GO:0030520

GO:0030522

GO:0032355

GO:0032991

GO:0033146

GO:0034056

GO:0034121

GO:0034641

GO:0035327

GO:0040007

GO:0042592

GO:0042802

GO:0042981

GO:0043124

GO:0043167

GO:0043226

GO:0043401

GO:0043433

GO:0043565

GO:0043627

GO:0045893

GO:0045899

GO:0045944

GO:0046872

GO:0048146

GO:0048856

GO:0048863

GO:0050727

GO:0051091

GO:0051117

GO:0051276

GO:0051897

GO:0060065

GO:0060068

GO:0060523

GO:0060527

GO:0060687

GO:0060745

GO:0060749

GO:0060750

GO:0065003

GO:0071168

GO:0071391

GO:0071392

GO:0097550

GO:1903799

GO:1990837

HMNXSV003001759

Hs.247938.0.S1_3p_at

Hs.247976.0.S1_3p_s_at

ILMN_1678535

TC06001104.hg

TC06003132.hg

TC06003133.hg

X03635_at

X86816_at

g11907834_3p_a_at

g4503602_3p_at

Participates

as a candidate of

ESRs [cytosol] (Homo sapiens)

Other forms of this molecule

PalmS-ER alpha36 [cytosol]

PalmS-ER alpha36 [plasma membrane]

Me87-PalmS-ER alpha36 [plasma membrane]

Inferred To

Esr1 [cytosol] (Mus musculus)

Esr1 [cytosol] (Rattus norvegicus)

ERR [cytosol] (Drosophila melanogaster)

esr1 [cytosol] (Danio rerio)

ESR1 [cytosol] (Canis familiaris)

Cross References

RefSeq

NP_001116214.1, XP_011533846.1, NP_001278170.1, XP_016865865.1, XP_006715438.1, XP_011533845.1, XP_016865867.1, NP_001315029.1, NP_001116213.1, XP_016865868.1, NP_001278159.1, XP_016865870.1, NP_000116.2, NP_001116212.1, XP_016865869.1, XP_011533847.1, XP_016865866.1

ZINC - World Drugs

ESR1_HUMAN

OpenTargets

ENSG00000091831

ZINC - FDA approved

ESR1_HUMAN

ZINC - Substances

ESR1_HUMAN

ZINC target

P03372

ZINC - Biogenic

ESR1_HUMAN

PRO

P03372

PDB

6OWC, 5TN7, 1X7R, 5TMV, 1XP6, 2LLQ, 6VJD, 4PP6, 5KRH, 4TUZ, 5KR9, 4Q50, 5FQP, 4MG5, 4ZNH, 1G50, 6VVP, 3OSA, 1HCQ, 2IOG, 3CBM, 5DWI, 5DYD, 3Q95, 4ZN7, 5TM2, 5KCF, 2QAB, 5FQV, 3UU7, 6VPF, 5DXP, 2JF9, 2B23, 5E0X, 4IU7, 5U2B, 6VIG, 5KCU, 5TLL, 5DZ1, 1XQC, 2AYR, 3ERT, 5TN4, 5DKB, 5DRM, 2G5O, 5TMS, 5E14, 5TM3, 5DXK, 3CBO, 7KCD, 5DXQ, 2QSE, 6VJ1, 4IV4, 1AKF, 2QH6, 2IOK, 5TMW, 4MGD, 5DZ3, 5DUE, 5TMM, 4PXM, 5TM6, 5EI1, 5DXB, 2POG, 4PPP, 1X7E, 5TN5, 2QXM, 4O6F, 1UOM, 6VMU, 5KRA, 3UUA, 6HKF, 2QGW, 5DKS, 5KCW, 1QKU, 5DLR, 6HHP, 1ERR, 5KRI, 2YAT, 5DL4, 6CHZ, 5W9C, 5TM4, 5TMT, 5GS4, 6VGH, 5KRL, 6CZN, 6PSJ, 5GTR, 5T0X, 5EIT, 3HLV, 5N10, 5TMZ, 5T92, 5DUG, 4IV2, 1L2I, 5KRM, 1HCP, 2B1V, 4IVW, 1XP1, 2QA8, 6IAR, 2YJA, 6CBZ, 5TLX, 5DZ0, 4ZN9, 6V8T, 5TMO, 4IW6, 4Q13, 2Q6J, 5DVS, 4IUI, 5DZH, 5TM7, 5DWJ, 2R6W, 6HKB, 5DRJ, 5DY8, 5TMU, 6HMU, 5DP0, 2BJ4, 1YIM, 5HYR, 5T1Z, 5W9D, 6WOK, 5U2D, 3UUC, 5TLY, 2QA6, 5DWG, 4IW8, 5FQS, 4ZNS, 5EGV, 1R5K, 6V87, 1ERE, 4XI3, 5DMC, 4MG8, 5AAV, 4PPS, 5TLM, 5TN1, 4IVY, 5UFW, 5KCC, 2R6Y, 5TN8, 5TLT, 4JDD, 5TMQ, 5T97, 5KRC, 1QKT, 4MGC, 4DMA, 5TLD, 6CHW, 5E15, 4MGA, 6SQ0, 4MGB, 1PCG, 2JFA, 3CBP, 5DXR, 5TM8, 5AK2, 5JMM, 5TLU, 5TLO, 6PET, 5DKE, 5DUH, 5DID, 5DIG, 5KRO, 5FQT, 5WGQ, 1ZKY, 5TM5, 4ZNV, 6D0F, 5KCT, 5KD9, 6PIT, 6PFM, 4MG6, 1SJ0, 2G44, 5TN9, 5E19, 5DU5, 5TN3, 1XPC, 5DYB, 2LLO, 5ACC, 6SBO, 5FQR, 3OS8, 5DK9, 6SUO, 4JC3, 5DWE, 4MG7, 3L03, 5KRJ, 2OCF, 2I0J, 2QE4, 6C42, 2QZO, 4IWF, 1YIN, 2QXS, 5E1C, 6DF6, 5DTV, 5TLF, 5DZI, 2P15, 5TM1, 4MG9, 3OS9, 6TJM, 5KCD, 4ZNU, 1GWQ, 5UFX, 2FAI, 5E0W, 4TV1, 1XP9, 5TN6, 5TM9, 6B0F, 3UUD, 5DMF, 2QGT, 4ZNT, 5DXM, 6DFN, 5KRF, 4IWC, 4ZNW, 1GWR, 5DVV, 1A52, 5TLG, 5DI7, 5KCE, 5DXE, 5EHJ, 6VPK, 3HM1, 5KRK, 5DKG, 2OUZ, 5DXG, 5WGD, 5DIE, 5TML, 2Q70, 5TLV, 5AAU, 5TLP, 2B1Z, 5TMR, 3DT3, 3ERD, 5DX3, 6TL3, 4AA6, 5TNB, 2QR9

ZINC - Investigational

ESR1_HUMAN

ZINC - Metabolites

ESR1_HUMAN

GeneCards

P03372

HPA

ENSG00000091831-ESR1

Ensembl

ENSG00000091831, ENSP00000405330, ENSP00000387500, ENSP00000342630, ENST00000338799, ENST00000443427, ENST00000440973, ENST00000206249, ENSP00000206249

ZINC - Predictions - Purchasable

ESR1_HUMAN

Orphanet

15995

HMDB Protein

HMDBP02078

Interactors (255)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P03372 ESR1	8	SUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.87	11
UniProt:P12931 SRC	6	p-Y416-SRC [cytosol] (R-HSA-8964276) SRC [cytosol] (R-HSA-9628701) p-Y419-SRC [nucleoplasm] (R-HSA-8937690) MyrG-SRC [plasma membrane] (R-HSA-8876922) MyrG,p-Y530-SRC [plasma membrane] (R-HSA-377598) MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408)	0.848	12
UniProt:Q15788 NCOA1	3	NCOA1 (868-1441) [nucleoplasm] (R-HSA-5603230) SUMO1-K732,K774-NCOA1 [nucleoplasm] (R-HSA-4085291) NCOA1 [nucleoplasm] (R-HSA-442496)	0.835	8
UniProt:Q04206 RELA	6	MeK310-RELA [nucleoplasm] (R-HSA-8865233) SUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) p-S276-RELA [nucleoplasm] (R-HSA-5624468) RELA [cytosol] (R-HSA-168172) RELA [nucleoplasm] (R-HSA-177676)	0.832	9
UniProt:P38398 BRCA1	27	SUMO1-K109-BRCA1 [nucleoplasm] (R-HSA-2997644) SUMO2,3-BRCA1 [nucleoplasm] (R-HSA-2997624) BRCA1 C64R [nucleoplasm] (R-HSA-9700907) BRCA1 C61G [nucleoplasm] (R-HSA-9700890) BRCA1 C39Y [nucleoplasm] (R-HSA-9700938) BRCA1 H41R [nucleoplasm] (R-HSA-9700921) BRCA1 C24R [nucleoplasm] (R-HSA-9663198) BRCA1 H41A [nucleoplasm] (R-HSA-9700927) BRCA1 M18T [nucleoplasm] (R-HSA-9700911) BRCA1 C47G [nucleoplasm] (R-HSA-9700941) BRCA1 C64G [nucleoplasm] (R-HSA-9700899) BRCA1 C44F [nucleoplasm] (R-HSA-9700944) BRCA1 T37R [nucleoplasm] (R-HSA-9700934) BRCA1 C27A [nucleoplasm] (R-HSA-9700916) BRCA1 H41Q [nucleoplasm] (R-HSA-9700923) BRCA1 Q12Tfs5 [nucleoplasm] (R-HSA-9700953) BRCA1 E23Afs18 [nucleoplasm] (R-HSA-9700959) BRCA1 C61Y [nucleoplasm] (R-HSA-9700894) BRCA1 C24F [nucleoplasm] (R-HSA-9663206) BRCA1 E23Rfs18 [nucleoplasm] (R-HSA-9700960) BRCA1 E23Vfs17 [nucleoplasm] (R-HSA-9700967) p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-5683800) K6PolyUb,p-S988,S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-9707298) BRCA1 [nucleoplasm] (R-HSA-50949) K6PolyUb-BRCA1 [nucleoplasm] (R-HSA-9701022) K6PolyUb,p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-9707290) p-S1387,S1423,S1524,S1547-BRCA1 [nucleoplasm] (R-HSA-75234)	0.811	16
IntAct:EBI-5590876 TFF1			0.788	6
UniProt:P06401 PGR	3	PGR [cytosol] (R-HSA-8948964) SUMO1-K7,K388,K531-PGR [nucleoplasm] (R-HSA-4341032) PGR [nucleoplasm] (R-HSA-3008952)	0.774	20
UniProt:P55345 ANM2			0.75	9
UniProt:Q6PL18 ATAD2	1	ATAD2 [nucleoplasm] (R-HSA-8937250)	0.737	5
UniProt:Q9H1R3 MYLK2			0.725	5
UniProt:P60709 ACTB	5	Unfolded ACTB [cytosol] (R-HSA-390462) ACTB(1-375) [lysosomal membrane] (R-HSA-196160) ACTB(1-375) [nucleoplasm] (R-HSA-3321990) ACTB(1-375) [cytosol] (R-HSA-201861) ACTB(1-375) [plasma membrane] (R-HSA-196016)	0.723	6
UniProt:P62701 RPS4X	2	RPS4X [cytosol] (R-HSA-72375) RPS4X [nucleoplasm] (R-HSA-6798713)	0.69	4
UniProt:P62854 RPS26	2	RPS26 [cytosol] (R-HSA-72359) RPS26 [nucleoplasm] (R-HSA-6798708)	0.69	5
UniProt:Q969Q0 RPL36AL	1	RPL36AL [cytosol] (R-HSA-8868805)	0.69	5
UniProt:Q9BQ69 MACD1			0.69	6
UniProt:P05388 RPLP0	1	RPLP0 [cytosol] (R-HSA-72396)	0.69	4
UniProt:Q9Y6Q9 NCOA3	2	p-S857 NCOA3 [nucleoplasm] (R-HSA-5687005) NCOA3 [nucleoplasm] (R-HSA-442488)	0.688	4
UniProt:P29279 CCN2	1	CTGF [extracellular region] (R-HSA-561148)	0.682	7
UniProt:P19838-PRO_0000030311 NFKB1			0.676	3
UniProt:Q02447 SP3	3	SUMO2-K551-SP3 [nucleoplasm] (R-HSA-6804456) SUMO1-K551-SP3 [nucleoplasm] (R-HSA-3247472) SP3 [nucleoplasm] (R-HSA-2160951)	0.667	4
UniProt:Q6NYC1 JMJD6	1	JMJD6 [nucleoplasm] (R-HSA-4754226)	0.649	8
UniProt:Q9Y294 ASF1A	1	ASF1A [nucleoplasm] (R-HSA-417169)	0.647	4
UniProt:P06576 ATP5F1B	6	ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B [mitochondrial inner membrane] (R-HSA-1299441) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B [mitochondrial matrix] (R-HSA-164576)	0.643	4
UniProt:P17844 DDX5	4	DDX5 [cytosol] (R-HSA-9682643) DDX5 [nucleoplasm] (R-HSA-3900136) SUMO2-K53-DDX5 [nucleoplasm] (R-HSA-3900186) SUMO1-K53-DDX5 [nucleoplasm] (R-HSA-3900041)	0.643	4
UniProt:P60660 MYL6	2	MYL6 [cytosol] (R-HSA-419186) p-S20-MYL6 [cytosol] (R-HSA-445778)	0.642	3
UniProt:O15164 TRIM24	4	TRIM24-p-2Y-FGFR1 fusion [cytosol] (R-HSA-1839012) TRIM24-FGFR1 fusion [cytosol] (R-HSA-1614442) TRIM24-BRAF fusion [cytosol] (R-HSA-6802477) p-TRIM24-BRAF fusion [cytosol] (R-HSA-6802555)	0.641	3
UniProt:P60763 RAC3	3	RAC3 [plasma membrane] (R-HSA-195338) RAC3 [endoplasmic reticulum membrane] (R-HSA-9714693) RAC3 [cytosol] (R-HSA-195335)	0.639	5
UniProt:Q8N895 ZN366			0.633	6
UniProt:O43524 FOXO3	9	p-S215 FOXO3 [cytosol] (R-HSA-5687014) p-S215 FOXO3 [nucleoplasm] (R-HSA-5687010) FOXO3 [cytosol] (R-HSA-5687032) p-S43,S173,S294,S325-FOXO3 [nucleoplasm] (R-HSA-8870627) p-S43,S173,S294,S325-FOXO3 [cytosol] (R-HSA-8870560) Ac-K242,K259,K271,K290,K569-FOXO3 [nucleoplasm] (R-HSA-9620514) FOXO3 [nucleoplasm] (R-HSA-199305) p-T32,S253,S315-FOXO3 [nucleoplasm] (R-HSA-199289) p-T32,S253,S315-FOXO3 [cytosol] (R-HSA-9614413)	0.632	7
UniProt:Q03989 ARI5A			0.625	9
UniProt:P53041 PPP5C	2	PPP5C [cytosol] (R-HSA-5675402) PPP5C [nucleoplasm] (R-HSA-5683410)	0.625	4
UniProt:P23771 GATA3	2	PolyUb-GATA3 [nucleoplasm] (R-HSA-6783009) GATA3 [nucleoplasm] (R-HSA-996768)	0.623	4
UniProt:P05627 Jun	5	Jun [cytosol] (R-MMU-8868685) p-S63,S73-Jun [cytosol] (R-MMU-8868678) Jun [nucleoplasm] (R-MMU-3261183) phospho-Jun [nucleoplasm] (R-MMU-450237) Jun [nucleoplasm] (R-MMU-450250)	0.616	6
UniProt:Q9Y3R0 GRIP1	2	GRIP1 [plasma membrane] (R-HSA-416638) GRIP1 [cytosol] (R-HSA-416633)	0.609	2
UniProt:Q5JTH9 RRP12			0.597	4
UniProt:P61513 RPL37A	1	RPL37A [cytosol] (R-HSA-72468)	0.597	4
UniProt:P27635 RPL10	1	RPL10 [cytosol] (R-HSA-72402)	0.597	4
UniProt:Q96GQ7 DDX27			0.597	4
UniProt:Q9BVP2 GNL3	1	GNL3 [nucleoplasm] (R-HSA-8869324)	0.597	4
UniProt:O43823 AKAP8			0.597	4
UniProt:Q13547 HDAC1	2	SUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030) HDAC1 [nucleoplasm] (R-HSA-205021)	0.597	4
UniProt:Q01130 SRSF2	1	SRSF2 [nucleoplasm] (R-HSA-72033)	0.597	4
UniProt:P21333 FLNA	3	p-S2152-FLNA [cytosol] (R-HSA-5669246) FLNA [extracellular region] (R-HSA-350712) FLNA [cytosol] (R-HSA-210019)	0.597	3
UniProt:P10276 RARA	3	SUMO2-K166,K171,K399-RARA [nucleoplasm] (R-HSA-4341042) SUMO2-K166,177,399-p-S219,269-RARA [nucleoplasm] (R-HSA-5334830) RARA [nucleoplasm] (R-HSA-446164)	0.597	4
UniProt:P06396 GSN	7	GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940) GSN [extracellular region] (R-HSA-6806510) GSN [secretory granule lumen] (R-HSA-6801486) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.597	3
UniProt:P62263 RPS14	2	RPS14 [cytosol] (R-HSA-72333) RPS14 [nucleoplasm] (R-HSA-6790669)	0.597	3
UniProt:P11142 HSPA8	10	HSPA8 [nucleoplasm] (R-HSA-5082380) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [cytosol] (R-HSA-264476)	0.597	3
UniProt:Q92841 DDX17	2	SUMO1-K50-DDX17 [nucleoplasm] (R-HSA-3900104) DDX17 [nucleoplasm] (R-HSA-3900090)	0.597	3
UniProt:P35579 MYH9	1	MYH9 [cytosol] (R-HSA-419173)	0.597	3
UniProt:P06401-1 PGR			0.593	4
UniProt:Q12802 AKAP13	1	AKAP13 [cytosol] (R-HSA-2975983)	0.593	3
UniProt:Q9Y6C7 L3R2A			0.593	3
UniProt:O60869 EDF1			0.59	3
UniProt:P17676 CEBPB	3	p-T235-CEBPB [nucleoplasm] (R-HSA-3857343) p-T235, S321-CEBPB [nucleoplasm] (R-HSA-3857339) CEBPB [nucleoplasm] (R-HSA-381378)	0.59	2
UniProt:P18846 ATF1	2	ATF1 [nucleoplasm] (R-HSA-199900) p-S63-ATF1 [nucleoplasm] (R-HSA-199897)	0.59	3
UniProt:Q15596 NCOA2	3	NCOA2 (869-1464) [nucleoplasm] (R-HSA-5603186) SUMO1-K239,K731,K788-NCOA2 [nucleoplasm] (R-HSA-4085305) NCOA2 [nucleoplasm] (R-HSA-376398)	0.584	5
UniProt:O43251 RBFOX2	1	RBFOX2 [nucleoplasm] (R-HSA-6803504)	0.581	4
UniProt:Q96AQ6-1 PBXIP1			0.576	3
IntAct:EBI-10099285 VITA2			0.576	5
UniProt:Q86Y37 CACL1			0.571	5
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.564	3
UniProt:Q9UHF7 TRPS1			0.564	4
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.564	3
UniProt:P00523 SRC	9	SRC [cytosol] (R-GGA-9628701) SRC [plasma membrane] (R-GGA-190535) phospho-SRC [cytosol] (R-GGA-8964276) SRC [plasma membrane] (R-GGA-8876922) Src [cytosol] (R-GGA-3928468) phospho-SRC [plasma membrane] (R-GGA-377598) phospho-SRC [cytosol] (R-GGA-377592) phospho-SRC [plasma membrane] (R-GGA-1810408) SRC [cytosol] (R-GGA-191648)	0.564	2
UniProt:P48552 NRIP1	2	NRIP1 [nucleoplasm] (R-HSA-4086031) SUMO1-K756,K1154-NRIP1 [nucleoplasm] (R-HSA-4086057)	0.564	3
UniProt:P08047 SP1	1	SP1 [nucleoplasm] (R-HSA-1592223)	0.558	2
UniProt:Q6ZQX7-4 Q6ZQX74			0.556	3
UniProt:Q16881-4 TXNRD1			0.556	4
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:P62962 Pfn1	2	Pfn1 [cytosol] (R-MMU-350757) Profilin-1 [extracellular region] (R-MMU-350698)	0.556	3
UniProt:O76024 WFS1	3	p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q9UBK2 PPARGC1A	4	p-T263,S266,T299-PPARGC1A [nucleoplasm] (R-HSA-1592224) SUMO1-K184-PPARGC1A [nucleoplasm] (R-HSA-3903023) p-T178,S539-PPARGC1A [nucleoplasm] (R-HSA-1592204) PPARGC1A [nucleoplasm] (R-HSA-442481)	0.553	2
UniProt:Q9BZ95 NSD3	1	WHSC1L1 [nucleoplasm] (R-HSA-1183230)	0.547	3
IntAct:EBI-2695616 ERE			0.544	2
UniProt:Q96Q04 LMTK3			0.544	3
UniProt:Q14151 SAFB2			0.544	2
UniProt:Q09472 EP300	5	Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) SUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.536	2
UniProt:Q92731 ESR2	5	PalmS-ESR2 [plasma membrane] (R-HSA-9021059) PalmS-ESR2 [cytosol] (R-HSA-9020979) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.532	3
UniProt:P06748 NPM1	5	p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [cytosol] (R-HSA-3008211) NPM1 [nucleoplasm] (R-HSA-606320) SUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) SUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.532	3
UniProt:P82673 MRPS35	1	MRPS35 [mitochondrial inner membrane] (R-HSA-5368185)	0.527	3
UniProt:P62269 RPS18	2	RPS18 [cytosol] (R-HSA-72341) RPS18 [nucleoplasm] (R-HSA-6798701)	0.527	2
UniProt:Q99832 CCT7	1	CCT7 [cytosol] (R-HSA-390451)	0.527	2
UniProt:P68363 TUBA1B	9	Ac K40 TUBA1B [axonemal microtubule] (R-HSA-5624854) AcK-TUBA1B [cytosol] (R-HSA-5618285) TUBA1B folding intermediate [cytosol] (R-HSA-392797) TUBA1B unfolded [cytosol] (R-HSA-392781) L-isoglutamyl polyglycyl-TUBA1B [cytosol] (R-HSA-8867436) Polyglutamyl-TUBA1B [cytosol] (R-HSA-8867435) TUBA1B [cytosol] (R-HSA-191691) TUBA1B [axonemal microtubule] (R-HSA-5610434) TUBA1B(1-450) [cytosol] (R-HSA-8955581)	0.527	3
UniProt:P05109 S100A8	3	S100A8 [secretory granule lumen] (R-HSA-6804772) S100A8 [cytosol] (R-HSA-9626834) S100A8 [extracellular region] (R-HSA-5432846)	0.527	2
UniProt:Q96SB4 SRPK1			0.527	3
UniProt:Q9HCM4 EPB41L5	1	EPB41L5 [cytosol] (R-HSA-6797564)	0.527	3
UniProt:Q9NX58 LYAR			0.527	3
UniProt:Q8NI36 WDR36	1	WDR36 [nucleoplasm] (R-HSA-6790623)	0.527	3
UniProt:O00165 HAX1			0.527	2
IntAct:EBI-1265559 MYC			0.527	3
UniProt:Q13823 NOG2			0.527	3
UniProt:P08865 RPSA	2	RPSA [cytosol] (R-HSA-72389) RPSA [nucleoplasm] (R-HSA-6798722)	0.527	3
UniProt:Q14684 RRP1B			0.527	3
UniProt:P60866 RPS20	2	RPS20 [cytosol] (R-HSA-72349) RPS20 [nucleoplasm] (R-HSA-6798727)	0.527	2
UniProt:Q9NPD3 EXOSC4	2	EXOSC4 [cytosol] (R-HSA-430013) EXOSC4 [nucleoplasm] (R-HSA-6791503)	0.527	3
UniProt:Q7Z406 MYH14	1	MYH14 [cytosol] (R-HSA-419176)	0.527	2
UniProt:O95793 STAU1			0.527	2
UniProt:P27708 CAD	1	CAD [cytosol] (R-HSA-73452)	0.527	3
UniProt:Q9Y399 MRPS2	1	MRPS2 [mitochondrial inner membrane] (R-HSA-8866677)	0.527	3
UniProt:Q9BUF5 TUBB6	6	TUBB6 unfolded [cytosol] (R-HSA-392780) TUBB6 folding intermediate [cytosol] (R-HSA-392787) Polyglycyl-TUBB6 [cytosol] (R-HSA-8867396) TUBB6 [cytosol] (R-HSA-191698) TUBB6 [axonemal microtubule] (R-HSA-5610438) Polyglutamyl-TUBB6 [cytosol] (R-HSA-8867399)	0.527	3
UniProt:P56192 MARS1	1	MARS [cytosol] (R-HSA-379657)	0.527	3
UniProt:O75110 ATP9A	1	ATP9A [plasma membrane] (R-HSA-939754)	0.527	3
UniProt:P82650 MRPS22	1	MRPS22 [mitochondrial inner membrane] (R-HSA-5368259)	0.527	3
UniProt:P12268 IMPDH2	4	IMPDH2 [ficolin-1-rich granule lumen] (R-HSA-6803330) IMPDH2 [cytosol] (R-HSA-57350) IMPDH2 [extracellular region] (R-HSA-6806455) IMPDH2 [secretory granule lumen] (R-HSA-6803323)	0.527	3
UniProt:Q92665 MRPS31	1	MRPS31 [mitochondrial inner membrane] (R-HSA-5368198)	0.527	3
UniProt:O43432 EIF4G3	1	EIF4G3 [cytosol] (R-HSA-1678827)	0.527	3
UniProt:Q96EY7 PTCD3	1	PTCD3 [mitochondrial inner membrane] (R-HSA-5368165)	0.527	3
UniProt:Q8IYT4 KATL2			0.527	2
UniProt:Q9UBF2 COPG2	4	COPG2 [transport vesicle] (R-HSA-6808753) COPG2 [endoplasmic reticulum membrane] (R-HSA-6810962) COPG2 [cytosol] (R-HSA-6807747) COPG2 [Golgi membrane] (R-HSA-6808751)	0.527	3
UniProt:Q92552 MRPS27	1	MRPS27 [mitochondrial inner membrane] (R-HSA-5368214)	0.527	3
UniProt:P62952 BLCAP			0.527	2
UniProt:O60568 PLOD3	1	PLOD3 [endoplasmic reticulum membrane] (R-HSA-1981135)	0.527	2
UniProt:Q9Y4P3 TBL2			0.527	3
UniProt:Q9NQZ2 UTP3	1	UTP3 [nucleoplasm] (R-HSA-6790637)	0.527	3
UniProt:Q9BRD0 BUD13			0.527	3
UniProt:Q9UN36 NDRG2			0.527	2
UniProt:Q7Z2W4 ZC3HAV1	2	p-ZC3HAV1-BRAF fusion [cytosol] (R-HSA-6802557) ZC3HAV1-BRAF fusion [cytosol] (R-HSA-6802506)	0.527	3
UniProt:O43175 PHGDH	1	PHGDH [cytosol] (R-HSA-977340)	0.527	3
UniProt:P05089 ARG1	4	ARG1 [specific granule lumen] (R-HSA-6801011) ARG1 [cytosol] (R-HSA-70561) ARG1 [extracellular region] (R-HSA-6806221) ARG1 [azurophil granule lumen] (R-HSA-6798764)	0.527	2
UniProt:Q8WUY1 THEM6			0.527	3
UniProt:Q9Y2R5 MRPS17	1	MRPS17 [mitochondrial inner membrane] (R-HSA-5368241)	0.527	2
UniProt:Q8NHW5 RLA0L			0.527	2
UniProt:Q9BVJ6 UTP14A	1	UTP14A [nucleoplasm] (R-HSA-6790695)	0.527	3
UniProt:Q9H3U1 UN45A			0.527	3
UniProt:P62191 PSMC1	2	PSMC1 [cytosol] (R-HSA-68768) PSMC1 [nucleoplasm] (R-HSA-174338)	0.527	3
UniProt:P60842 EIF4A1	1	EIF4A1 [cytosol] (R-HSA-72573)	0.527	3
UniProt:P25398 RPS12	2	RPS12 [cytosol] (R-HSA-72329) RPS12 [nucleoplasm] (R-HSA-6798715)	0.527	2
UniProt:Q15233 NONO			0.527	3
UniProt:P78362 SRPK2			0.527	3
UniProt:Q96HI0 SENP5	1	SENP5 [nucleoplasm] (R-HSA-2984297)	0.527	2
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.527	3
UniProt:Q7L2E3 DHX30			0.527	3
UniProt:Q99575 POP1	1	POP1 [nucleoplasm] (R-HSA-5696802)	0.527	3
UniProt:Q9BQ39 DDX50			0.527	3
UniProt:Q9Y3U8 RPL36	1	RPL36 [cytosol] (R-HSA-72464)	0.527	3
UniProt:Q8N201 INTS1	1	INTS1 [nucleoplasm] (R-HSA-6807446)	0.527	3
UniProt:Q8IXJ9 ASXL1	1	ASXL1 [nucleoplasm] (R-HSA-5689645)	0.527	2
UniProt:O00429 DNM1L	2	DNM1L [cytosol] (R-HSA-351943) DNM1L [mitochondrial outer membrane] (R-HSA-351942)	0.527	2
UniProt:Q15084 PDIA6	3	p-PDIA6 [endoplasmic reticulum lumen] (R-HSA-8957031) PDIA6 [endoplasmic reticulum membrane] (R-HSA-535530) PDIA6 [endoplasmic reticulum lumen] (R-HSA-3009049)	0.527	3
UniProt:P50454 SERPINH1	1	SERPINH1 [endoplasmic reticulum lumen] (R-HSA-2127480)	0.527	3
UniProt:P42224 STAT1	7	p-STAT1 [cytosol] (R-HSA-8950418) p-STAT1 [nucleoplasm] (R-HSA-8987140) p-Y701-STAT1 [nucleoplasm] (R-HSA-8985905) p-Y701-STAT1 [cytosol] (R-HSA-8951202) p-Y701-STAT1 [nucleoplasm] (R-HSA-6788624) p-Y701-STAT1 [cytosol] (R-HSA-3132766) STAT1 [cytosol] (R-HSA-629622)	0.527	3
UniProt:P62244 RPS15A	2	RPS15A [cytosol] (R-HSA-72345) RPS15A [nucleoplasm] (R-HSA-6791191)	0.527	3
UniProt:Q96L91 EP400	1	EP400 [nucleoplasm] (R-HSA-3321987)	0.527	3
UniProt:Q04637 EIF4G1	2	EIF4G1 [cytosol] (R-HSA-72584) p-S1108,S1148,S1192-EIF4G1 [cytosol] (R-HSA-165762)	0.527	3
UniProt:Q92754 TFAP2C	3	TFAP2C [cytosol] (R-HSA-8864579) SUMO1-K10-TFAP2C [nucleoplasm] (R-HSA-3234071) TFAP2C [nucleoplasm] (R-HSA-3234058)	0.527	3
UniProt:P46940 IQGAP1	3	IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [plasma membrane] (R-HSA-381681)	0.527	3
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	2
UniProt:Q9UBL3 ASH2L	1	ASH2L [nucleoplasm] (R-HSA-1629834)	0.527	4
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.527	3
UniProt:Q15291 RBBP5	1	RBBP5 [nucleoplasm] (R-HSA-1629836)	0.527	4
UniProt:P12814 ACTN1	3	ACTN1 [platelet alpha granule lumen] (R-HSA-349724) ACTN1 [cytosol] (R-HSA-354096) ACTN1 [extracellular region] (R-HSA-349722)	0.527	3
UniProt:O14686 KMT2D	1	KMT2D [nucleoplasm] (R-HSA-1183219)	0.525	3
UniProt:P42229 STAT5A	5	p-STAT5A [nucleoplasm] (R-HSA-8982836) p-Y694-STAT5A [nucleoplasm] (R-HSA-507995) p-Y649-STAT5A [cytosol] (R-HSA-8980151) p-Y694-STAT5A [cytosol] (R-HSA-507936) STAT5A [cytosol] (R-HSA-380747)	0.524	2
UniProt:Q9H467 CUED2			0.524	2
UniProt:Q9BTK6 PAGR1	1	PAGR1 [nucleoplasm] (R-HSA-5619374)	0.524	5
UniProt:Q99966 CITED1	1	CITED1 [nucleoplasm] (R-HSA-8864301)	0.524	3
UniProt:Q00987 MDM2	11	SUMO1-K182-MDM2 [nucleoplasm] (R-HSA-3000408) PolyUb-MDM2 [nucleoplasm] (R-HSA-6782472) MDM2 [plasma membrane] (R-HSA-416843) MDM2 [endocytic vesicle membrane] (R-HSA-416849) p-S166,S188,T218-MDM2 [nucleoplasm] (R-HSA-6792862) PolyUb,p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6795669) p-5S,T-MDM2 [nucleoplasm] (R-HSA-6804954) MDM2 [nucleoplasm] (R-HSA-69486) MDM2 [cytosol] (R-HSA-198644) p-S166,S188-MDM2 [cytosol] (R-HSA-198638) p-S166,S188-MDM2 [nucleoplasm] (R-HSA-6793669)	0.508	2
UniProt:Q9JLI4 NCOA6			0.508	2
UniProt:Q99623 PHB2	1	PHB2 [mitochondrial inner membrane] (R-HSA-8953721)	0.508	4
UniProt:P59598	1	Asxl1 [nucleoplasm] (R-MMU-5689645)	0.508	2
UniProt:P20290-2 BTF3			0.508	5
UniProt:Q12778 FOXO1	5	p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306) FOXO1 [nucleoplasm] (R-HSA-199300) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158) Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) p-S215 FOXO1 [nucleoplasm] (R-HSA-5692651)	0.508	2
UniProt:Q60974 Ncor1	3	Ncor1 [nucleoplasm] (R-MMU-442459) Ncor1 [cytosol] (R-MMU-1253324) Ncor1 [nucleoplasm] (R-MMU-442501)	0.508	2
UniProt:Q9NV06 DCAF13	1	DCAF13 [nucleoplasm] (R-HSA-6790673)	0.499	2
UniProt:O95835 LATS1	2	LATS1 [cytosol] (R-HSA-2028562) p-S909,T1097-LATS1 [cytosol] (R-HSA-2028551)	0.499	2
UniProt:PGR ENSG00000082175			0.499	3
UniProt:Q9NPJ4 PNRC2	1	PNRC2 [cytosol] (R-HSA-8879146)	0.488	2
UniProt:P27986 PIK3R1	15	PIK3R1 K379E [plasma membrane] (R-HSA-8944148) PIK3R1 G376R [plasma membrane] (R-HSA-2399717) PIK3R1 Y463_L466del [plasma membrane] (R-HSA-2399546) PIK3R1 H450_E451del [plasma membrane] (R-HSA-2399545) PIK3R1 R574_T576del [plasma membrane] (R-HSA-2399544) PIK3R1 D560Y [plasma membrane] (R-HSA-2399421) PIK3R1 N564D [plasma membrane] (R-HSA-2399427) PIK3R1 K459del [plasma membrane] (R-HSA-2399554) PIK3R1 N564K [plasma membrane] (R-HSA-2399431) PIK3R1 D560H [plasma membrane] (R-HSA-2399432) PIK3R1 R574I [plasma membrane] (R-HSA-2399536) PIK3R1 R574T [plasma membrane] (R-HSA-2399540) K63polyUb-PIK3R1 [cytosol] (R-HSA-3080572) PIK3R1 [plasma membrane] (R-HSA-198365) PIK3R1 [cytosol] (R-HSA-74789)	0.483	7
UniProt:Q925T6	2	Grip1 [plasma membrane] (R-MMU-416638) Grip1 [cytosol] (R-MMU-416633)	0.482	2
UniProt:P83881 RPL36A	1	RPL36A [cytosol] (R-HSA-72480)	0.462	2
UniProt:O76021 RL1D1			0.462	2
UniProt:Q9NYF8 BCLF1			0.462	2
UniProt:Q07020 RPL18	1	RPL18 [cytosol] (R-HSA-72420)	0.462	2
UniProt:P61978 HNRNPK	2	HNRNPK [nucleoplasm] (R-HSA-71945) SUMO2-K422-HNRNPK [nucleoplasm] (R-HSA-4570532)	0.462	2
UniProt:Q01844 EWS			0.462	2
UniProt:Q8IYB3 SRRM1	2	SRRM1 [cytosol] (R-HSA-159255) SRRM1 [nucleoplasm] (R-HSA-156781)	0.462	2
UniProt:P39023 RPL3	1	RPL3 [cytosol] (R-HSA-72448)	0.462	2
UniProt:O00159 MYO1C	1	MYO1C [cytosol] (R-HSA-1449619)	0.462	2
UniProt:Q14444 CAPR1			0.462	2
UniProt:Q6PJG2 MDEAS			0.462	2
UniProt:P05141 SLC25A5	1	SLC25A5 [mitochondrial inner membrane] (R-HSA-49743)	0.462	2
UniProt:Q00610 CLTC	6	CLTC [clathrin-coated endocytic vesicle membrane] (R-HSA-5138450) CLTC [plasma membrane] (R-HSA-2980668) CLTC [endolysosome membrane] (R-HSA-8870827) CLTC [cytosol] (R-HSA-8856820) CLTC [lysosomal membrane] (R-HSA-2980660) CLTC [trans-Golgi network membrane] (R-HSA-5333703)	0.462	2
UniProt:Q9NVP1 DDX18			0.462	2
UniProt:P02786 TFRC	5	TFRC(1-760) [Golgi membrane] (R-HSA-434330) TFRC(1-760) [clathrin-coated endocytic vesicle membrane] (R-HSA-8869124) TFRC(1-760) [cytoplasmic vesicle membrane] (R-HSA-434196) TFRC(1-760) [plasma membrane] (R-HSA-917983) TFRC(1-760) [endosome membrane] (R-HSA-8961829)	0.462	2
UniProt:P62917 RPL8	1	RPL8 [cytosol] (R-HSA-72490)	0.462	2
UniProt:P04843 RPN1	1	RPN1 [endoplasmic reticulum membrane] (R-HSA-264994)	0.462	2
UniProt:P04844 RPN2	1	RPN2 [endoplasmic reticulum membrane] (R-HSA-264937)	0.462	2
UniProt:P36578 RPL4	1	RPL4 [cytosol] (R-HSA-72474)	0.462	2
UniProt:P46013 KI67			0.462	2
UniProt:Q14669 TRIP12	1	TRIP12 [cytosol] (R-HSA-976046)	0.462	2
UniProt:Q9P035 HACD3	1	PTPLAD1 [endoplasmic reticulum membrane] (R-HSA-5676074)	0.462	2
UniProt:P11388 TOP2A	3	SUMO2,3-TOP2A [nucleoplasm] (R-HSA-4641298) TOP2A [nucleoplasm] (R-HSA-1362276) SUMO1-K-TOP2A [nucleoplasm] (R-HSA-4641367)	0.462	2
UniProt:P83731 RPL24	1	RPL24 [cytosol] (R-HSA-72434)	0.462	2
UniProt:P68032 ACTC1	1	ACTC1 [cytosol] (R-HSA-390536)	0.462	2
UniProt:Q02543 RPL18A	1	RPL18A [cytosol] (R-HSA-72422)	0.462	2
UniProt:O43795 MYO1B			0.462	2
UniProt:Q12905 ILF2	4	ILF2 [specific granule lumen] (R-HSA-6799611) ILF2 [tertiary granule lumen] (R-HSA-6800995) ILF2 [extracellular region] (R-HSA-6799684) ILF2 [ficolin-1-rich granule lumen] (R-HSA-6801001)	0.462	2
UniProt:P18124 RPL7	1	RPL7 [cytosol] (R-HSA-72486)	0.462	2
UniProt:O00571 DDX3X	3	DDX3X [extracellular region] (R-HSA-6806507) DDX3X [ficolin-1-rich granule lumen] (R-HSA-6801273) DDX3X [secretory granule lumen] (R-HSA-6801275)	0.462	2
UniProt:P62424 RPL7A	1	RPL7A [cytosol] (R-HSA-72488)	0.462	2
UniProt:Q32P51 RA1L2			0.462	2
UniProt:Q02880 TOP2B	2	SUMO1-K-TOP2B [nucleoplasm] (R-HSA-4641297) TOP2B [nucleoplasm] (R-HSA-4641359)	0.462	2
UniProt:Q14980 NUMA1	3	NUMA1 [nucleoplasm] (R-HSA-380443) p-T2055-NUMA1 [nucleoplasm] (R-HSA-380473) p-NUMA1 [cytosol] (R-HSA-380484)	0.462	2
UniProt:Q9BZE4 NOG1			0.462	2
UniProt:O00567 NOP56	2	NOP56 [cytosol] (R-HSA-391293) NOP56 [nucleoplasm] (R-HSA-6790696)	0.462	2
UniProt:Q9NVI7 ATD3A			0.462	2
UniProt:P61313 RPL15	1	RPL15 [cytosol] (R-HSA-72416)	0.462	2
UniProt:P35268 RPL22	1	RPL22 [cytosol] (R-HSA-72428)	0.462	2
UniProt:A0A024RC46 A0A024RC46			0.462	2
UniProt:P14923 JUP	6	JUP [cornified envelope] (R-HSA-8847739) JUP [cytosol] (R-HSA-201598) JUP [specific granule lumen] (R-HSA-6799534) JUP [extracellular region] (R-HSA-6806309) JUP [ficolin-1-rich granule lumen] (R-HSA-6801028) JUP [plasma membrane] (R-HSA-437260)	0.462	2
UniProt:Q96HS1 PGAM5			0.462	2
UniProt:Q02878 RPL6	1	RPL6 [cytosol] (R-HSA-72484)	0.462	2
UniProt:P50914 RPL14	1	RPL14 [cytosol] (R-HSA-72414)	0.462	2
UniProt:P18621 RPL17	1	RPL17 [cytosol] (R-HSA-72418)	0.462	2
UniProt:P26373 RPL13	1	RPL13 [cytosol] (R-HSA-72410)	0.462	2
UniProt:P84098 RPL19	1	RPL19 [cytosol] (R-HSA-72424)	0.462	2
UniProt:P26368 U2AF2	1	U2AF2 [nucleoplasm] (R-HSA-71987)	0.462	2
UniProt:P46776 RPL27A	1	RPL27A [cytosol] (R-HSA-72442)	0.462	2
UniProt:Q9Y2W1 THRAP3	1	THRAP3 [nucleoplasm] (R-HSA-8932115)	0.462	2
UniProt:Q8TDD1 DDX54			0.462	2
UniProt:O43143 DHX15	1	DHX15 [nucleoplasm] (R-HSA-5688097)	0.462	2
UniProt:Q9H0A0 NAT10	1	NAT10 [nucleoplasm] (R-HSA-6791008)	0.462	2
UniProt:Q14498 RBM39			0.462	2
UniProt:P02787 TF	6	TF [secretory granule lumen] (R-HSA-350704) apoTF [clathrin-coated endocytic vesicle membrane] (R-HSA-8869140) p-TF [endoplasmic reticulum lumen] (R-HSA-8957001) TF [endoplasmic reticulum lumen] (R-HSA-8956763) apoTF [endosome membrane] (R-HSA-917974) apoTF [extracellular region] (R-HSA-350754)	0.462	2
UniProt:Q8IY81 FTSJ3	1	FTSJ3 [nucleoplasm] (R-HSA-6791507)	0.462	2
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) SUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.462	2
UniProt:O43390 HNRNPR	1	HNRNPR [nucleoplasm] (R-HSA-71951)	0.462	2
UniProt:Q96PK6 RBM14	1	RBM14 [nucleoplasm] (R-HSA-8938345)	0.462	2
UniProt:Q16629 SRSF7	1	SRSF7 [nucleoplasm] (R-HSA-72029)	0.462	2
UniProt:O60832 DKC1	1	DKC1 [nucleoplasm] (R-HSA-163102)	0.462	2
UniProt:P62266 RPS23	2	RPS23 [cytosol] (R-HSA-72353) RPS23 [nucleoplasm] (R-HSA-6791209)	0.462	2
UniProt:P46781 RPS9	2	RPS9 [cytosol] (R-HSA-72387) RPS9 [nucleoplasm] (R-HSA-6790663)	0.462	2
UniProt:Q9BQG0 MYBBP1A	1	MYBBP1A [nucleoplasm] (R-HSA-5250650)	0.462	2
UniProt:P62753 RPS6	3	p-5S-RPS6 [cytosol] (R-HSA-165727) RPS6 [nucleoplasm] (R-HSA-6790606) RPS6 [cytosol] (R-HSA-72381)	0.462	2
UniProt:P09874 PARP1	4	SUMO1-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551686) SUMO2,3-K203,K486-PARP1 [nucleoplasm] (R-HSA-4551617) PAR-PARP1 [nucleoplasm] (R-HSA-5651713) PARP1 [nucleoplasm] (R-HSA-201568)	0.462	2
UniProt:Q08211 DHX9	2	DHX9 [nucleoplasm] (R-HSA-53517) DHX9 [cytosol] (R-HSA-847700)	0.462	2
UniProt:P15880 RPS2	3	Me2aR-RPS2 [cytosol] (R-HSA-8879138) RPS2 [nucleoplasm] (R-HSA-6790655) RPS2 [cytosol] (R-HSA-72347)	0.462	2
UniProt:P0CG47 UBB	109	UBB(1-76) [endocytic vesicle membrane] (R-HSA-939231) UBB(77-152) [endocytic vesicle membrane] (R-HSA-939253) UBB(153-228) [endocytic vesicle membrane] (R-HSA-939171) Ub-33-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783023) Ub-110-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783008) Ub-186-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783046) Ub-215-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783002) Ub-63-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783148) Ub-139-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783012) Ub-158-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783162) Ub-6-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783014) Ub-82-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783015) Ub-163-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783025) Ub-87-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6782998) Ub-11-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783109) Ub-124-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783131) Ub-200-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783100) Ub-48-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783165) Ub-182-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783160) Ub-29-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783070) Ub-106-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783103) Ub-27-UBB(1-76) [mitochondrial outer membrane] (R-HSA-6783038) Ub-180-UBB(153-228) [mitochondrial outer membrane] (R-HSA-6783114) Ub-104-UBB(77-152) [mitochondrial outer membrane] (R-HSA-6783149) N6-glycyl-L-lysine-UBB(1-76) [cytosol] (R-HSA-8869049) N6-glycyl-L-lysine-UBB(153-228) [cytosol] (R-HSA-8869046) N6-glycyl-L-lysine-UBB(77-152) [cytosol] (R-HSA-8869047) adenylatedG152-UBB(77-152) [nucleoplasm] (R-HSA-8852094) adenylatedG228-UBB(153-228) [nucleoplasm] (R-HSA-8852104) adenylatedG76-UBB(1-76) [nucleoplasm] (R-HSA-8852101) UBB [cytosol] (R-HSA-8853516) adenylatedG76-UBB(1-76) [cytosol] (R-HSA-8852121) adenylatedG228-UBB(153-228) [cytosol] (R-HSA-8852049) adenylatedG152-UBB(77-152) [cytosol] (R-HSA-8852113) Ub-124-UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943100) Ub-48-UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943138) Ub-200-UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943117) UBB(153-228) [plasma membrane] (R-HSA-3149455) UBB(1-76) [plasma membrane] (R-HSA-3149453) UBB(77-152) [plasma membrane] (R-HSA-3149463) UBB(77-152) [endosome membrane] (R-HSA-939251) UBB(1-76) [endosome membrane] (R-HSA-939240) UBB(153-228) [endosome membrane] (R-HSA-939247) UBB(153-228) [endoplasmic reticulum membrane] (R-HSA-8943098) UBB(77-152) [endoplasmic reticulum membrane] (R-HSA-8943111) UBB(1-76) [endoplasmic reticulum membrane] (R-HSA-8943078) Ub-106-UBB(77-152) [cytosol] (R-HSA-5689191) Ub-182-UBB(153-228) [cytosol] (R-HSA-5689214) Ub-29-UBB(1-76) [cytosol] (R-HSA-5689207) Ub-158-UBB(153-228) [cytosol] (R-HSA-5689099) Ub-82-UBB(77-152) [cytosol] (R-HSA-5689080) Ub-6-UBB(1-76) [cytosol] (R-HSA-5689075) Ub-33-UBB(1-76) [cytosol] (R-HSA-5689198) Ub-186-UBB(153-228) [cytosol] (R-HSA-5689146) Ub-110-UBB(77-152) [cytosol] (R-HSA-5689203) Ub-27-UBB(1-76) [cytosol] (R-HSA-5689161) Ub-104-UBB(77-152) [cytosol] (R-HSA-5689139) Ub-180-UBB(153-228) [cytosol] (R-HSA-5689138) Ub-11-UBB(1-76) [cytosol] (R-HSA-3095929) Ub-163-UBB(153-228) [cytosol] (R-HSA-3095932) Ub-87-UBB(77-152) [cytosol] (R-HSA-3095917) Ub-139-UBB(77-152) [endosome membrane] (R-HSA-939217) Ub-215-UBB(153-228) [endosome membrane] (R-HSA-939193) Ub-63-UBB(1-76) [endosome membrane] (R-HSA-939167) Ub-139-UBB(77-152) [plasma membrane] (R-HSA-939867) Ub-63-UBB(1-76) [plasma membrane] (R-HSA-939872) Ub-215-UBB(153-228) [plasma membrane] (R-HSA-939852) Ub-27-UBB(1-76) [nucleoplasm] (R-HSA-6782673) Ub-180-UBB(153-228) [nucleoplasm] (R-HSA-6782604) Ub-104-UBB(77-152) [nucleoplasm] (R-HSA-6782627) Ub-106-UBB(77-152) [nucleoplasm] (R-HSA-6782652) Ub-182-UBB(153-228) [nucleoplasm] (R-HSA-6782665) Ub-29-UBB(1-76) [nucleoplasm] (R-HSA-6782595) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-6782527) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-6782505) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-6782478) Ub-11-UBB(1-76) [nucleoplasm] (R-HSA-6782649) Ub-87-UBB(77-152) [nucleoplasm] (R-HSA-6782607) Ub-163-UBB(153-228) [nucleoplasm] (R-HSA-6782598) Ub-186-UBB(153-228) [nucleoplasm] (R-HSA-6782655) Ub-110-UBB(77-152) [nucleoplasm] (R-HSA-6782591) Ub-33-UBB(1-76) [nucleoplasm] (R-HSA-6782601) UBB(77-152) [nucleoplasm] (R-HSA-939870) UBB(1-76) [nucleoplasm] (R-HSA-939847) UBB(153-228) [nucleoplasm] (R-HSA-939854) Ub-48-UBB(1-76) [nucleoplasm] (R-HSA-5683040) Ub-124-UBB(77-152) [nucleoplasm] (R-HSA-5683036) Ub-200-UBB(153-228) [nucleoplasm] (R-HSA-5683038) Ub-139-UBB(77-152) [nucleoplasm] (R-HSA-6782488) Ub-63-UBB(1-76) [nucleoplasm] (R-HSA-6782489) Ub-215-UBB(153-228) [nucleoplasm] (R-HSA-6782475) Ub-82-UBB(77-152) [nucleoplasm] (R-HSA-6782683) Ub-6-UBB(1-76) [nucleoplasm] (R-HSA-6782600) Ub-158-UBB(153-228) [nucleoplasm] (R-HSA-6782639) UBB(153-228) [late endosome lumen] (R-HSA-9660014) UBB(77-152) [late endosome lumen] (R-HSA-9660021) UBB(1-76) [late endosome lumen] (R-HSA-9660017) Ub-48-UBB(1-76) [cytosol] (R-HSA-939249) Ub-124-UBB(77-152) [cytosol] (R-HSA-939225) Ub-200-UBB(153-228) [cytosol] (R-HSA-939197) UBB(153-228) [cytosol] (R-HSA-939230) UBB(77-152) [cytosol] (R-HSA-939213) UBB(1-76) [cytosol] (R-HSA-939214) UBB(77-152) [lysosomal lumen] (R-HSA-9660011) UBB(1-76) [lysosomal lumen] (R-HSA-9660024) UBB(153-228) [lysosomal lumen] (R-HSA-9660025) Ub-63-UBB(1-76) [cytosol] (R-HSA-939224) Ub-215-UBB(153-228) [cytosol] (R-HSA-939168) Ub-139-UBB(77-152) [cytosol] (R-HSA-939235)	0.462	2
UniProt:Q8IZL8 PELP1	1	PELP1 [nucleoplasm] (R-HSA-3826531)	0.462	2
UniProt:P11387 TOP1	2	SUMO1-K117-TOP1 [nucleoplasm] (R-HSA-4641364) TOP1 [nucleoplasm] (R-HSA-4641363)	0.462	2
UniProt:P09651 HNRNPA1	1	HNRNPA1 [nucleoplasm] (R-HSA-71927)	0.462	2
UniProt:P62249 RPS16	2	RPS16 [cytosol] (R-HSA-72337) RPS16 [nucleoplasm] (R-HSA-6791196)	0.462	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.462	2
UniProt:P35637 FUS	1	FUS [nucleoplasm] (R-HSA-72040)	0.462	2
UniProt:P62241 RPS8	2	RPS8 [cytosol] (R-HSA-72385) RPS8 [nucleoplasm] (R-HSA-6791203)	0.462	2
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.462	2
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.462	2
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.462	2
UniProt:P17480 UBTF	2	UBTF [nucleoplasm] (R-HSA-73683) p-UBTF [nucleoplasm] (R-HSA-76039)	0.462	2
UniProt:P38159 RBMX	2	RBMX [cytosol] (R-HSA-9715135) RBMX [nucleoplasm] (R-HSA-71939)	0.462	2
UniProt:P61247 RPS3A	2	RPS3A [cytosol] (R-HSA-72373) RPS3A [nucleoplasm] (R-HSA-6791182)	0.462	2
UniProt:P51991 HNRNPA3	1	HNRNPA3 [nucleoplasm] (R-HSA-71931)	0.462	2
UniProt:P19338 NCL	1	NCL [nucleoplasm] (R-HSA-6791213)	0.462	2
UniProt:P40429 RPL13A	2	RPL13A [cytosol] (R-HSA-72412) p-RPL13A [cytosol] (R-HSA-156829)	0.462	2
UniProt:P52597 HNRNPF	2	HNRNPF [plasma membrane] (R-HSA-8950714) HNRNPF [nucleoplasm] (R-HSA-71937)	0.462	2

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