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SENP5 [nucleoplasm]
Stable Identifier
R-HSA-2984297
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Sentrin-specific protease 5 ecNumber3.4.22.68/ecNumber, SENP5_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
Processing and activation of SUMO (Homo sapiens)
SUMO is proteolytically processed (Homo sapiens)
SENP1,2,5 proteolytically process SUMO1 (Homo sapiens)
SENP1,2,5 [nucleoplasm] (Homo sapiens)
SENP5 [nucleoplasm] (Homo sapiens)
SENP1,2,5 proteolytically process SUMO2 (Homo sapiens)
SENP1,2,5 [nucleoplasm] (Homo sapiens)
SENP5 [nucleoplasm] (Homo sapiens)
SENP1,2,5 proteolytically process SUMO3 (Homo sapiens)
SENP1,2,5 [nucleoplasm] (Homo sapiens)
SENP5 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
16608850
Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3
Gong, L
,
Yeh, ET
J. Biol. Chem.
2006
External Reference Information
External Reference
UniProt:Q96HI0 SENP5
Gene Names
SENP5, FKSG45
Chain
chain:1-755
Reference Genes
BioGPS Gene:205564 SENP5
COSMIC (genes):SENP5 SENP5
CTD Gene:205564 SENP5
dbSNP Gene:205564 SENP5
ENSEMBL:ENSG00000119231 SENP5
HGNC:28407 SENP5
KEGG Gene (Homo sapiens):205564 SENP5
Monarch:205564 SENP5
NCBI Gene:205564 SENP5
OMIM:612845 SENP5
UCSC:Q96HI0 SENP5
Reference Transcript
RefSeq:XM_011512544.2 SENP5
RefSeq:XM_017005870.1 SENP5
RefSeq:NM_152699.4 SENP5
RefSeq:NM_001308045.1 SENP5
Other Identifiers
0002190746
11721920_at
11721921_at
11752237_a_at
16950035
205564
213184_at
222110_at
2659632
2659633
2659636
2659637
2659638
2659639
2659643
2659644
2659645
2659646
2659653
2659655
2659658
2659660
2659661
2659662
2659668
2659669
2659670
2659671
2659673
2659675
32082_at
44188_at
4852000C_3p_s_at
50755_at
57703_at
8084971
A_14_P115220
A_14_P135486
A_23_P18102
A_23_P29504
A_32_P114447
A_32_P32653
GE56140
GE79883
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005730
GO:0005886
GO:0006464
GO:0006508
GO:0007049
GO:0008150
GO:0008233
GO:0008234
GO:0016787
GO:0016925
GO:0016926
GO:0019783
GO:0043226
GO:0051301
Hs.13138.0.S1_3p_at
Hs.15787.0.S1_3p_at
ILMN_1675501
ILMN_3251634
PH_hs_0001262
TC03001101.hg
Participant Of
hasMember
SENP1,2,5 [nucleoplasm]
Inferred To
Homologues of SENP5 [nucleoplasm] (Caenorhabditis elegans)
Homologues of SENP5 [nucleoplasm] (Drosophila melanogaster)
Dmel\CG32110 [nucleoplasm] (Drosophila melanogaster)
ULP1 [nucleoplasm] (Saccharomyces cerevisiae)
Ulp1 [nucleoplasm] (Drosophila melanogaster)
ulp-1 [nucleoplasm] (Caenorhabditis elegans)
ulp-5 [nucleoplasm] (Caenorhabditis elegans)
ulp1 [nucleoplasm] (Schizosaccharomyces pombe)
Senp5 [nucleoplasm] (Mus musculus)
LOC103689978 [nucleoplasm] (Rattus norvegicus)
SENP5 [nucleoplasm] (Bos taurus)
SENP5 [nucleoplasm] (Canis familiaris)
SENP5 [nucleoplasm] (Dictyostelium discoideum)
SENP5 [nucleoplasm] (Drosophila melanogaster)
SENP5 [nucleoplasm] (Gallus gallus)
SENP5 [nucleoplasm] (Plasmodium falciparum)
SENP5 [nucleoplasm] (Sus scrofa)
SENP5 [nucleoplasm] (Xenopus tropicalis)
senp5 [nucleoplasm] (Danio rerio)
Cross References
RefSeq
NP_689912.2
,
XP_011510846.1
,
XP_016861359.1
,
NP_001294974.1
OpenTargets
ENSG00000119231
GeneCards
Q96HI0
HPA
ENSG00000119231-SENP5
Ensembl
ENSP00000390231
,
ENST00000445299
,
ENSP00000327197
,
ENSG00000119231
,
ENST00000323460
PRO
Q96HI0
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03372 ESR1
8
SUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.527
2
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