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apoTF [endosome membrane]
Stable Identifier
R-HSA-917974
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
Serotransferrin
Locations in the PathwayBrowser
Expand all
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
Fe3+ dissociates from holoTF:TFRC dimer (Homo sapiens)
apoTF:TFRC dimer [endosome membrane] (Homo sapiens)
apoTF [endosome membrane] (Homo sapiens)
holoTF:TFRC dimer [endosome membrane] (Homo sapiens)
holoTF [endosome membrane] (Homo sapiens)
apoTF [endosome membrane] (Homo sapiens)
apoTF:TFRC dimer translocates from endosome membrane to plasma membrane (Homo sapiens)
apoTF:TFRC dimer [endosome membrane] (Homo sapiens)
apoTF [endosome membrane] (Homo sapiens)
holoTF:TFRC dimer translocates from plasma membrane to endosome membrane (Homo sapiens)
holoTF:TFRC dimer [endosome membrane] (Homo sapiens)
holoTF [endosome membrane] (Homo sapiens)
apoTF [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02787 TF
Gene Names
TF, PRO1400
Chain
signal peptide:1-19, chain:20-698
Reference Genes
COSMIC (genes):TF TF
dbSNP Gene:7018 TF
ENSEMBL:ENSG00000091513 TF
Participates
as a component of
apoTF:TFRC dimer [endosome membrane] (Homo sapiens)
holoTF [endosome membrane] (Homo sapiens)
Other forms of this molecule
apoTF [clathrin-coated endocytic vesicle membrane]
TF [secretory granule lumen]
apoTF [extracellular region]
p-TF [endoplasmic reticulum lumen]
TF [endoplasmic reticulum lumen]
Inferred To
apoTF [endosome membrane]
(Bos taurus)
apoTF [endosome membrane]
(Gallus gallus)
apoTF [endosome membrane]
(Mus musculus)
apoTF [endosome membrane]
(Rattus norvegicus)
apoTF [endosome membrane]
(Sus scrofa)
Interactors (36)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P02786 TFRC
5
TFRC(1-760) [endosome membrane]
(R-HSA-8961829)
TFRC(1-760) [plasma membrane]
(R-HSA-917983)
TFRC(1-760) [cytoplasmic vesicle membrane]
(R-HSA-434196)
TFRC(1-760) [Golgi membrane]
(R-HSA-434330)
TFRC(1-760) [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869124)
0.852
7
UniProt:A5K736 A5K736
0.733
9
UniProt:Q9K0U9 TBPA
0.632
4
UniProt:Q09057 TBPB1
0.618
3
UniProt:Q9K0V0 TBPB
0.558
2
UniProt:Q9BXS9-3 SLC26A6
0.556
3
UniProt:Q96KR6 F210B
0.556
3
UniProt:O15173 PGRMC2
4
PGRMC2 [nuclear envelope]
(R-HSA-9707674)
PGRMC2 [nucleoplasm]
(R-HSA-9707859)
PGRMC2 [endoplasmic reticulum membrane]
(R-HSA-9714349)
PGRMC2 [endosome membrane]
(R-HSA-9715090)
0.556
3
UniProt:O43315 AQP9
1
AQP9 [plasma membrane]
(R-HSA-431761)
0.556
3
UniProt:A8MZ59 LEUTX
1
LEUTX [nucleoplasm]
(R-HSA-9817277)
0.556
3
UniProt:O15529 GPR42
0.556
3
UniProt:Q8NBJ4 GOLM1
2
p-GOLM1 [endoplasmic reticulum lumen]
(R-HSA-8956938)
GOLM1 [endoplasmic reticulum lumen]
(R-HSA-8956710)
0.556
3
UniProt:Q9Y282 ERGI3
0.556
3
UniProt:Q8TED1 GPX8
1
GPX8 [endoplasmic reticulum lumen]
(R-HSA-3341303)
0.556
3
UniProt:P08034 GJB1
2
GJB1 [endoplasmic reticulum membrane]
(R-HSA-190656)
GJB1 [endoplasmic reticulum-Golgi intermediate compartment]
(R-HSA-190636)
0.556
3
UniProt:Q99523 SORT1
2
SORT1 [Golgi membrane]
(R-HSA-434332)
SORT1 [cytoplasmic vesicle membrane]
(R-HSA-434221)
0.556
3
UniProt:Q4KMG9 TM52B
0.556
3
UniProt:O00501 CLDN5
2
CLDN5 [cell junction]
(R-HSA-421264)
CLDN5 [plasma membrane]
(R-HSA-419991)
0.556
3
UniProt:Q96TC7 RMD3
0.556
3
UniProt:Q7Z7G2 CPLX4
0.556
3
UniProt:Q9GZR5 ELOVL4
1
ELOVL4 [endoplasmic reticulum membrane]
(R-HSA-548705)
0.556
3
UniProt:Q8N9I0 SYT2
3
SYT2 [synaptic vesicle membrane]
(R-HSA-194786)
SYT2 [plasma membrane]
(R-HSA-168795)
SYT2 [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869116)
0.556
3
UniProt:O43278-2 SPINT1
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
UniProt:P05091 ALDH2
1
ALDH2 [mitochondrial matrix]
(R-HSA-71718)
0.527
2
UniProt:Q9BSW7 SYT17
0.527
2
UniProt:Q8N412 STPG2
0.527
2
UniProt:P60033 CD81
1
CD81 [plasma membrane]
(R-HSA-197933)
0.527
6
UniProt:P35219 CAH8
0.527
2
UniProt:Q9H788 SH24A
0.527
2
UniProt:Q9H8H2 DDX31
0.527
2
UniProt:O15232 MATN3
3
MATN3 [extracellular region]
(R-HSA-2426297)
p-MATN3 [endoplasmic reticulum lumen]
(R-HSA-8957026)
MATN3 [endoplasmic reticulum lumen]
(R-HSA-8956719)
0.527
2
UniProt:Q16659 MAPK6
6
p-3S,T MAPK6 [nucleoplasm]
(R-HSA-5692665)
MAPK6 [nucleoplasm]
(R-HSA-5692686)
p-S189 MAPK6 [nucleoplasm]
(R-HSA-5687015)
p-S189 MAPK6 [cytosol]
(R-HSA-5687019)
MAPK6 [cytosol]
(R-HSA-5686979)
ub-MAPK6 [cytosol]
(R-HSA-5687000)
0.527
2
UniProt:Q9NQZ2 UTP3
1
UTP3 [nucleoplasm]
(R-HSA-6790637)
0.527
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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