Reactome | TOM1 [specific granule membrane]

TOM1 [specific granule membrane]

Stable Identifier

R-HSA-6800923

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Target of Myb protein 1, TOM1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O60784 TOM1

Gene Names

TOM1

Chain

chain:1-492

Reference Genes

BioGPS Gene:10043 TOM1

COSMIC (genes):TOM1 TOM1

CTD Gene:10043 TOM1

dbSNP Gene:10043 TOM1

ENSEMBL:ENSG00000100284 TOM1

HGNC:11982 TOM1

KEGG Gene (Homo sapiens):10043 TOM1

Monarch:10043 TOM1

NCBI Gene:10043 TOM1

OMIM:604700 TOM1

UCSC:O60784 TOM1

Reference Transcript

Other Identifiers

0003850037

10043

11735898_s_at

11740164_x_at

11741580_a_at

11752491_x_at

11753021_x_at

11754300_x_at

11756811_x_at

16929529

202807_s_at

39134_at

3944085

3944086

3944092

3944094

3944099

3944100

3944103

3944104

3944108

3944109

3944111

3944112

3944114

3944115

3944116

3944119

3944124

3944125

3944126

3944127

3944128

8072659

A_14_P126890

A_23_P103084

A_33_P3751889

GE55175

GO:0002376

GO:0003674

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005764

GO:0005768

GO:0005769

GO:0005773

GO:0005829

GO:0005886

GO:0006810

GO:0006886

GO:0006897

GO:0007165

GO:0008150

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0030276

GO:0031410

GO:0035577

GO:0035579

GO:0043226

GO:0043312

GO:0070062

HMNXSV003028297

ILMN_1813148

ILMN_2082314

PH_hs_0000980

TC22000257.hg

TC22001088.hg

g4885636_3p_s_at

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

TOM1 [azurophil granule membrane]

TOM1 [plasma membrane]

Inferred To

DmTOM1 [specific granule membrane] (Drosophila melanogaster)

Tom1 [specific granule membrane] (Mus musculus)

Tom1 [specific granule membrane] (Rattus norvegicus)

TOM1 [specific granule membrane] (Bos taurus)

TOM1 [specific granule membrane] (Caenorhabditis elegans)

TOM1 [specific granule membrane] (Canis familiaris)

TOM1 [specific granule membrane] (Gallus gallus)

TOM1 [specific granule membrane] (Sus scrofa)

tom1 [specific granule membrane] (Danio rerio)

Cross References

RefSeq

NP_005479.1, NP_001129202.1, NP_001129204.1, NP_001129201.1

OpenTargets

ENSG00000100284

GeneCards

O60784

HPA

ENSG00000100284-TOM1

Ensembl

ENST00000411850, ENST00000425375, ENST00000449058, ENSP00000413697, ENSG00000100284, ENST00000447733, ENSP00000394924, ENSP00000398876, ENSP00000394466

PRO

O60784

Orphanet

29698

PDB

1WRD, 2N9D, 2N2N, 1ELK, 6J56

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [cytosol] (R-HSA-446885) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.749	5
UniProt:P0CG53	79	UBB [endocytic vesicle membrane] (R-BTA-939231) UBB [endocytic vesicle membrane] (R-BTA-939253) UBB [endocytic vesicle membrane] (R-BTA-939171) UBB [mitochondrial outer membrane] (R-BTA-6783023) UBB [mitochondrial outer membrane] (R-BTA-6783008) UBB [mitochondrial outer membrane] (R-BTA-6783046) UBB [mitochondrial outer membrane] (R-BTA-6783002) UBB [mitochondrial outer membrane] (R-BTA-6783148) UBB [mitochondrial outer membrane] (R-BTA-6783012) UBB [mitochondrial outer membrane] (R-BTA-6783162) UBB [mitochondrial outer membrane] (R-BTA-6783014) UBB [mitochondrial outer membrane] (R-BTA-6783015) UBB [mitochondrial outer membrane] (R-BTA-6783025) UBB [mitochondrial outer membrane] (R-BTA-6782998) UBB [mitochondrial outer membrane] (R-BTA-6783109) UBB [mitochondrial outer membrane] (R-BTA-6783131) UBB [mitochondrial outer membrane] (R-BTA-6783100) UBB [mitochondrial outer membrane] (R-BTA-6783165) UBB [mitochondrial outer membrane] (R-BTA-6783160) UBB [mitochondrial outer membrane] (R-BTA-6783070) UBB [mitochondrial outer membrane] (R-BTA-6783103) UBB [mitochondrial outer membrane] (R-BTA-6783038) UBB [mitochondrial outer membrane] (R-BTA-6783114) UBB [mitochondrial outer membrane] (R-BTA-6783149) UBB [cytosol] (R-BTA-8853516) phospho-UBB [cytosol] (R-BTA-8852121) phospho-UBB [cytosol] (R-BTA-8852049) phospho-UBB [cytosol] (R-BTA-8852113) UBB [endosome membrane] (R-BTA-939251) UBB [endosome membrane] (R-BTA-939240) UBB [endosome membrane] (R-BTA-939247) UBB [cytosol] (R-BTA-5689191) UBB [cytosol] (R-BTA-5689214) UBB [cytosol] (R-BTA-5689207) UBB [cytosol] (R-BTA-5689099) UBB [cytosol] (R-BTA-5689080) UBB [cytosol] (R-BTA-5689075) UBB [cytosol] (R-BTA-5689198) UBB [cytosol] (R-BTA-5689146) UBB [cytosol] (R-BTA-5689203) UBB [cytosol] (R-BTA-5689161) UBB [cytosol] (R-BTA-5689139) UBB [cytosol] (R-BTA-5689138) UBB [cytosol] (R-BTA-3095929) UBB [cytosol] (R-BTA-3095932) UBB [cytosol] (R-BTA-3095917) UBB [nucleoplasm] (R-BTA-6782673) UBB [nucleoplasm] (R-BTA-6782604) UBB [nucleoplasm] (R-BTA-6782627) UBB [nucleoplasm] (R-BTA-6782652) UBB [nucleoplasm] (R-BTA-6782665) UBB [nucleoplasm] (R-BTA-6782595) UBB [nucleoplasm] (R-BTA-6782527) UBB [nucleoplasm] (R-BTA-6782505) UBB [nucleoplasm] (R-BTA-6782478) UBB [nucleoplasm] (R-BTA-6782649) UBB [nucleoplasm] (R-BTA-6782607) UBB [nucleoplasm] (R-BTA-6782598) UBB [cytosol] (R-BTA-939235) UBB [cytosol] (R-BTA-939168) UBB [cytosol] (R-BTA-939224) UBB [cytosol] (R-BTA-939214) UBB [cytosol] (R-BTA-939213) UBB [cytosol] (R-BTA-939230) UBB [cytosol] (R-BTA-939197) UBB [cytosol] (R-BTA-939225) UBB [cytosol] (R-BTA-939249) UBB [nucleoplasm] (R-BTA-6782639) UBB [nucleoplasm] (R-BTA-6782600) UBB [nucleoplasm] (R-BTA-6782683) UBB [nucleoplasm] (R-BTA-6782475) UBB [nucleoplasm] (R-BTA-6782489) UBB [nucleoplasm] (R-BTA-6782488) UBB [nucleoplasm] (R-BTA-939854) UBB [nucleoplasm] (R-BTA-939847) UBB [nucleoplasm] (R-BTA-939870) UBB [nucleoplasm] (R-BTA-6782601) UBB [nucleoplasm] (R-BTA-6782591) UBB [nucleoplasm] (R-BTA-6782655)	0.743	6
UniProt:Q7Z3T8 ZFYVE16	1	ZFYVE16 [early endosome membrane] (R-HSA-201645)	0.655	5

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