Reactome | TOM1 [specific granule membrane]

TOM1 [specific granule membrane]

Stable Identifier

R-HSA-6800923

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Target of Myb protein 1, TOM1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60784 TOM1

Gene Names

TOM1

Chain

chain:1-492

Reference Genes

BioGPS Gene:10043 TOM1

COSMIC (genes):TOM1 TOM1

CTD Gene:10043 TOM1

dbSNP Gene:10043 TOM1

ENSEMBL:ENSG00000100284.22 TOM1

HGNC:11982 TOM1

KEGG Gene (Homo sapiens):10043 TOM1

Monarch:10043 TOM1

NCBI Gene:10043 TOM1

OMIM:604700 TOM1

UCSC:O60784 TOM1

Reference Transcript

Other Identifiers

10043

11735898_s_at

11740164_x_at

11741580_a_at

11752491_x_at

11753021_x_at

11754300_x_at

11756811_x_at

16929529

202807_PM_s_at

202807_s_at

39134_at

3944085

3944086

3944092

3944094

3944099

3944100

3944103

3944104

3944108

3944109

3944111

3944112

3944114

3944115

3944116

3944119

3944124

3944125

3944126

3944127

3944128

8072659

A_14_P126890

A_23_P103084

A_33_P3751889

GE55175

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0005764

GO:0005768

GO:0005769

GO:0005773

GO:0005829

GO:0005886

GO:0006897

GO:0006914

GO:0007165

GO:0008092

GO:0008289

GO:0010008

GO:0010314

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0023052

GO:0030276

GO:0031410

GO:0031593

GO:0031901

GO:0032050

GO:0035091

GO:0035577

GO:0035579

GO:0043130

GO:0043226

GO:0061024

GO:0061753

GO:0061909

GO:0070062

GO:0070853

GO:1901098

GO:1904978

HMNXSV003028297

ILMN_1813148

ILMN_2082314

PH_hs_0000980

TC22000257.hg

TC22001088.hg

g4885636_3p_s_at

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

TOM1 [plasma membrane]

TOM1 [azurophil granule membrane]

Inferred To

DmTOM1 [specific granule membrane] (Drosophila melanogaster)

Tom1 [specific granule membrane] (Mus musculus)

Tom1 [specific granule membrane] (Rattus norvegicus)

TOM1 [specific granule membrane] (Bos taurus)

TOM1 [specific granule membrane] (Caenorhabditis elegans)

TOM1 [specific granule membrane] (Canis familiaris)

TOM1 [specific granule membrane] (Gallus gallus)

TOM1 [specific granule membrane] (Sus scrofa)

tom1 [specific granule membrane] (Danio rerio)

tom1 [specific granule membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001129202.1, NP_001129204.1, NP_001129201.1, NP_005479.1

OpenTargets

ENSG00000100284

HPA

ENSG00000100284-TOM1

GeneCards

O60784

Ensembl

ENST00000447733, ENSP00000394466, ENSP00000413697, ENSP00000394924, ENSP00000398876, ENST00000411850, ENST00000449058, ENSG00000100284, ENST00000425375

PRO

O60784

Pharos - Targets

O60784

Orphanet

29698

PDB

1WRD, 6J56, 1ELK, 2N2N, 2N9D

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H0E2 TOLLIP	4	TOLLIP [cytosol] (R-HSA-446885) TOLLIP [azurophil granule lumen] (R-HSA-6799709) TOLLIP [extracellular region] (R-HSA-6800448) TOLLIP [specific granule lumen] (R-HSA-6799719)	0.749	5
UniProt:P0CG53	20	UBB [endocytic vesicle membrane] (R-BTA-939208) UBB [nucleoplasm] (R-BTA-6798734) UBB [mitochondrial outer membrane] (R-BTA-6783024) UBB [mitochondrial outer membrane] (R-BTA-6783200) UBB [mitochondrial outer membrane] (R-BTA-6783040) UBB [mitochondrial outer membrane] (R-BTA-6783085) UBB [mitochondrial outer membrane] (R-BTA-6783075) UBB [mitochondrial outer membrane] (R-BTA-6783146) UBB [cytosol] (R-BTA-939248) UBB [cytosol] (R-BTA-939205) UBB [cytosol] (R-BTA-939202) UBB [nucleoplasm] (R-BTA-6782608) UBB [nucleoplasm] (R-BTA-6782503) UBB [nucleoplasm] (R-BTA-939849) UBB [nucleoplasm] (R-BTA-5683037) UBB [cytosol] (R-BTA-3095933) UBB [nucleoplasm] (R-BTA-6782679) UBB [nucleoplasm] (R-BTA-6782618) UBB [nucleoplasm] (R-BTA-6782593) UBB [nucleoplasm] (R-BTA-6782671)	0.743	6
UniProt:Q7Z3T8 ZFYVE16	1	ZFYVE16 [early endosome membrane] (R-HSA-201645)	0.655	5
UniProt:P03372 ESR1	8	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) PalmS-ESR1 [cytosol] (R-HSA-9020974) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) Me260-ESR1 [cytosol] (R-HSA-9632177) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.527	3

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