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NAT10 [nucleoplasm]
Stable Identifier
R-HSA-6791008
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
N-acetyltransferase 10 ecNumber2.3.1.-/ecNumber, NAT10_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
NAT10 acetylates cytidine-1337 and cytidine-1842 of 18S rRNA yielding 4-acetylcytidine-1377 and 4-acetylcytidine-1842 (Homo sapiens)
NAT10 [nucleoplasm] (Homo sapiens)
NAT10:THUMPD1 [nucleoplasm] (Homo sapiens)
NAT10 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H0A0 NAT10
Gene Names
NAT10, ALP, KIAA1709
Chain
chain:1-1025
Reference Genes
BioGPS Gene:55226 NAT10
COSMIC (genes):NAT10 NAT10
CTD Gene:55226 NAT10
dbSNP Gene:55226 NAT10
ENSEMBL:ENSG00000135372 NAT10
ENSEMBL_homo_sapiens_GENE:ENSG00000135372.10 NAT10
HGNC:29830 NAT10
KEGG Gene (Homo sapiens):55226 NAT10
Monarch:55226 NAT10
NCBI Gene:55226 NAT10
OMIM:609221 NAT10
UCSC:Q9H0A0 NAT10
Reference Transcript
RefSeq:NM_001144030.1 NAT10
RefSeq:NM_024662.2 NAT10
Other Identifiers
11716123_a_at
11716124_a_at
11741201_a_at
16723507
217884_PM_at
217884_at
3326253
3326255
3326256
3326258
3326260
3326261
3326262
3326263
3326264
3326265
3326268
3326270
3326272
3326273
3326275
3326276
3326280
3326281
3326284
3326286
3326287
3326288
3326290
3326291
3326292
3326296
3326298
3326300
3326301
3326302
3326305
3326307
3326308
3326311
3326312
3326313
3326314
43161_at
46251_at
55226
7939265
A_14_P107197
A_14_P118978
A_23_P87329
GE62310
GO:0000049
GO:0000154
GO:0000166
GO:0000781
GO:0003723
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005697
GO:0005730
GO:0006364
GO:0006399
GO:0006473
GO:0007010
GO:0008033
GO:0008080
GO:0010824
GO:0016020
GO:0016072
GO:0016740
GO:0016746
GO:0016747
GO:0030496
GO:0032040
GO:0032200
GO:0032211
GO:0034470
GO:0036211
GO:0042254
GO:0042274
GO:0043226
GO:0045727
GO:0051391
GO:0070182
GO:0106162
GO:1904812
GO:1990883
HMNXSV003044325
ILMN_1705594
PH_hs_0025718
TC11000325.hg
g13399321_3p_at
Participates
as a component of
NAT10:THUMPD1 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_001137502.1
,
NP_078938.2
OpenTargets
ENSG00000135372
GeneCards
Q9H0A0
HPA
ENSG00000135372-NAT10
Ensembl
ENST00000531159
,
ENSG00000135372
,
ENST00000257829
,
ENSP00000433011
,
ENSP00000257829
PRO
Q9H0A0
Pharos - Targets
Q9H0A0
PDB
7MQ9
,
7MQ8
,
6VLA
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15880 RPS2
3
RPS2 [nucleoplasm]
(R-HSA-6790655)
Me2aR-RPS2 [cytosol]
(R-HSA-8879138)
RPS2 [cytosol]
(R-HSA-72347)
0.669
4
UniProt:P62241 RPS8
2
RPS8 [nucleoplasm]
(R-HSA-6791203)
RPS8 [cytosol]
(R-HSA-72385)
0.527
2
UniProt:P62263 RPS14
2
RPS14 [nucleoplasm]
(R-HSA-6790669)
RPS14 [cytosol]
(R-HSA-72333)
0.527
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [cytosol]
(R-COV-9694300)
p-S188,206-N [cytosol]
(R-COV-9729324)
p-8S-N [cytosol]
(R-COV-9729335)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
0.527
2
UniProt:P08670 VIM
11
VIM(2-85) [cytosol]
(R-HSA-350264)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM [cytosol]
(R-HSA-201600)
Vimentin [late endosome lumen]
(R-HSA-9660019)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [lysosomal lumen]
(R-HSA-9659977)
0.527
2
UniProt:P62753 RPS6
4
RPS6 [nucleoplasm]
(R-HSA-6790606)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
RPS6 [cytosol]
(R-HSA-72381)
0.483
3
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
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