Reactome | ATP5B [mitochondrial inner membrane]

ATP5B [mitochondrial inner membrane]

Stable Identifier

R-HSA-1299441

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase beta chain, ATP synthase subunit beta, mitochondrial

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P06576 ATP5F1B

Gene Names

ATP5F1B, ATP5B, ATPMB, ATPSB

Chain

transit peptide:1-47, chain:48-529

Reference Genes

BioGPS Gene:506 ATP5F1B

COSMIC (genes):ATP5F1B ATP5F1B

CTD Gene:506 ATP5F1B

dbSNP Gene:506 ATP5F1B

ENSEMBL:ENSG00000110955 ATP5B

ENSEMBL_homo_sapiens_GENE:ENSG00000110955.9 ATP5F1B

HGNC:830 ATP5F1B

KEGG Gene (Homo sapiens):506 ATP5F1B

Monarch:506 ATP5F1B

NCBI Gene:506 ATP5F1B

OMIM:102910 ATP5F1B

Reference Transcript

RefSeq:NM_001686.3 ATP5F1B

Other Identifiers

11724190_s_at

11757873_x_at

16766260

201322_PM_at

201322_at

3458034

3458035

3458036

3458037

3458039

3458040

3458041

3458042

3458045

3458047

3458048

3458050

3458054

506

7964234

A_23_P33216

GE57035

GO:0000166

GO:0001525

GO:0001649

GO:0003824

GO:0005215

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005739

GO:0005743

GO:0005753

GO:0005754

GO:0005759

GO:0005886

GO:0006091

GO:0006629

GO:0006754

GO:0006811

GO:0006933

GO:0007155

GO:0009986

GO:0015986

GO:0016020

GO:0016469

GO:0016787

GO:0016874

GO:0016887

GO:0030154

GO:0031966

GO:0042288

GO:0042645

GO:0042776

GO:0043226

GO:0043532

GO:0043536

GO:0045259

GO:0045261

GO:0046034

GO:0046933

GO:0046961

GO:0048856

GO:0048870

GO:0051453

GO:0055085

GO:0055086

GO:0070062

GO:0098761

GO:0140657

GO:1901135

GO:1902600

HMNXSV003039648

ILMN_1772132

M19483_at

PH_hs_0019285

TC12001609.hg

g4502294_3p_at

Participates

as a candidate of

Cargo of TIMM23 SORT [mitochondrial inner membrane] (Homo sapiens)

Other forms of this molecule

ATP5F1B [mitochondrial matrix]

ATP5B(1-47) [mitochondrial matrix]

ATP5B(1-529) [cytosol]

ATP5B(1-529) [mitochondrial intermembrane space]

ATP5B(1-529) [mitochondrial inner membrane]

Cross References

RefSeq

NP_001677.2

Guide to Pharmacology - Targets

797

OpenTargets

ENSG00000110955

HPA

ENSG00000110955-ATP5F1B

GeneCards

P06576

Ensembl

ENST00000262030, ENSP00000262030, ENSG00000110955

PRO

P06576

Pharos - Targets

P06576

PDB

8H9U, 8H9L, 8H9S, 8H9I, 8H9V, 8H9T, 8H9P, 8H9E

HMDB Protein

HMDBP01465

Interactors (44)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N5M1 ATPF2			0.801	8
UniProt:P25705 ATP5F1A	3	ATP5A1(1-553) [mitochondrial intermembrane space] (R-HSA-1267978) ATP5A1(1-553) [cytosol] (R-HSA-1267955) ATP5F1A [mitochondrial matrix] (R-HSA-164575)	0.744	7
UniProt:Q9UII2 ATIF1			0.669	4
UniProt:P24539 ATP5PB	1	ATP5PB [mitochondrial inner membrane] (R-HSA-164537)	0.669	5
UniProt:Q5TC12 ATPF1			0.659	3
UniProt:P25106 ACKR3	1	CXCR7 [plasma membrane] (R-HSA-373859)	0.643	3
UniProt:P03372 ESR1	10	p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) p-S167-ESR1 [cytosol] (R-HSA-9841254) Me260-ESR1 [cytosol] (R-HSA-9632177) PalmS-ESR1 [cytosol] (R-HSA-9020974) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) ESR1 [nucleoplasm] (R-HSA-446168) ESR1 [cytosol] (R-HSA-9020968)	0.643	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	20
UniProt:Q5T1Q4 S35F1			0.589	2
UniProt:P28566 HTR1E	1	HTR1E [plasma membrane] (R-HSA-390960)	0.564	2
UniProt:O75947 ATP5PD	1	ATP5PD [mitochondrial inner membrane] (R-HSA-50522)	0.564	2
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.564	2
UniProt:P54253 ATX1			0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:Q8N448 LNX2			0.553	4
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.536	2
UniProt:Q99679 GPR21			0.527	2
UniProt:P41587 VIPR2	1	VIPR2 [plasma membrane] (R-HSA-420227)	0.527	3
UniProt:O60779 SLC19A2	1	SLC19A2 [plasma membrane] (R-HSA-199636)	0.527	2
UniProt:O60512 B4GALT3	1	B4GALT3 [Golgi membrane] (R-HSA-975922)	0.527	4
UniProt:Q96G23 CERS2	1	CERS2 [endoplasmic reticulum membrane] (R-HSA-428171)	0.527	2
UniProt:Q7Z7J7 LHPL4			0.527	2
UniProt:P0DTD1-PRO_0000449624 REP			0.527	2
UniProt:P18859 ATP5PF	1	ATP5PF [mitochondrial inner membrane] (R-HSA-164532)	0.527	3
UniProt:Q9NX36 DJC28			0.527	2
UniProt:P32241 VIPR1	1	VIPR1 [plasma membrane] (R-HSA-420157)	0.527	2
UniProt:O75964 ATP5MG	1	ATP5MG [mitochondrial inner membrane] (R-HSA-50518)	0.527	2
UniProt:P30049 ATP5F1D	1	ATP5F1D [mitochondrial matrix] (R-HSA-164574)	0.527	2
UniProt:O95136 S1PR2	1	S1PR2 [plasma membrane] (R-HSA-419419)	0.527	2
UniProt:Q5I7T1 ALG10B	1	ALG10B [endoplasmic reticulum membrane] (R-HSA-449653)	0.527	2
UniProt:P48047 ATP5PO	1	ATP5PO [mitochondrial inner membrane] (R-HSA-164533)	0.527	2
UniProt:P48201 ATP5MC3	1	ATP5MC3 [mitochondrial inner membrane] (R-HSA-5216110)	0.527	2
UniProt:Q8IUW5 RELL1			0.527	2
UniProt:P28335 HTR2C	1	HTR2C [plasma membrane] (R-HSA-390965)	0.527	2
UniProt:Q86VR2 RETR3			0.527	2
UniProt:Q9H244 P2RY12	1	P2RY12 [plasma membrane] (R-HSA-391959)	0.527	2
UniProt:P27449 ATP6V0C	7	ATP6V0C [endosome membrane] (R-HSA-912591) ATP6V0C [phagocytic vesicle membrane] (R-HSA-1222603) ATP6V0C [tertiary granule membrane] (R-HSA-6800991) ATP6V0C [plasma membrane] (R-HSA-6806254) ATP6V0C [azurophil granule membrane] (R-HSA-6799363) ATP6V0C [ficolin-1-rich granule membrane] (R-HSA-6800908) ATP6V0C [lysosomal membrane] (R-HSA-9640194)	0.527	3
UniProt:P25090 FPR2	4	FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335) FPR2 [tertiary granule membrane] (R-HSA-6803296) FPR2 [plasma membrane] (R-HSA-416408)	0.527	2
UniProt:Q9HC97 GPR35	1	GPR35 [plasma membrane] (R-HSA-3295332)	0.527	2
UniProt:Q5K4L6 SLC27A3	1	SLC27A3 [mitochondrial matrix] (R-HSA-5216184)	0.527	2
UniProt:P51451 BLK	2	MyrG2-BLK [plasma membrane] (R-HSA-9606871) BLK [cytosol] (R-HSA-983580)	0.527	2
UniProt:P36542 ATP5F1C	1	ATP5F1C [mitochondrial matrix] (R-HSA-164577)	0.499	2
UniProt:A0A0F6B1Q8 A0A0F6B1Q8			0.462	2
UniProt:P05919 vpu	6	VPU (P05919) protein [cytosol] (R-HIV-173223) VPU (P05919) [endoplasmic reticulum membrane] (R-HIV-180550) VPU (P05919) protein [extracellular region] (R-HIV-175522) VPU (P05919) protein [nucleoplasm] (R-HIV-175200) VPU (P05919) [Golgi membrane] (R-HIV-3149439) VPU (P05919) [plasma membrane] (R-HIV-3149423)	0.462	2

Cite Us!