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TUBA1B unfolded [cytosol]
Stable Identifier
R-HSA-392781
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Unfolded tubulin K-alpha-1, unfolded alpha K tubulin -1
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (Homo sapiens)
Formation of tubulin folding intermediates by CCT/TriC (Homo sapiens)
ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)
CCT/TRiC:ADP:non-native tubulin [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBA1B unfolded [cytosol] (Homo sapiens)
CCT/TRiC:ATP:unfolded tubulin complex [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBA1B unfolded [cytosol] (Homo sapiens)
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)
CCT/TRiC:ATP:unfolded tubulin complex [cytosol] (Homo sapiens)
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
TUBA1B unfolded [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P68363 TUBA1B
Gene Names
TUBA1B
Chain
chain:1-451, chain:1-450
Reference Genes
BioGPS Gene:10376 TUBA1B
COSMIC (genes):TUBA1B TUBA1B
CTD Gene:10376 TUBA1B
dbSNP Gene:10376 TUBA1B
ENSEMBL:ENSG00000123416 TUBA1B
ENSEMBL_homo_sapiens_GENE:ENSG00000123416.15 TUBA1B
HGNC:18809 TUBA1B
KEGG Gene (Homo sapiens):10376 TUBA1B
Monarch:10376 TUBA1B
NCBI Gene:10376 TUBA1B
OMIM:602530 TUBA1B
UCSC:P68363 TUBA1B
Reference Transcript
RefSeq:NM_006082.2 TUBA1B
Other Identifiers
10376
11744345_x_at
11756979_x_at
201090_PM_x_at
201090_x_at
209251_PM_x_at
211058_PM_x_at
211058_x_at
211072_PM_x_at
211072_x_at
211750_PM_x_at
212639_PM_x_at
212639_x_at
213646_PM_x_at
213646_x_at
2872626
32272_at
3344233
3344241
3344242
3413815
3413819
3413821
3413822
3413824
3453738
3453739
3453740
3453741
3453742
3453743
3453745
3453746
3453747
3453748
3453749
3453753
3453841
3453845
3453846
3640627
59760_f_at
7963046
GO:0000166
GO:0000226
GO:0000278
GO:0003723
GO:0003725
GO:0003824
GO:0003924
GO:0005198
GO:0005200
GO:0005515
GO:0005525
GO:0005737
GO:0005856
GO:0005874
GO:0005881
GO:0007010
GO:0007017
GO:0015630
GO:0016787
GO:0030705
GO:0031625
GO:0043226
GO:0051301
GO:0071353
HMNXSV003034622
Hs.240615.2.S1_3p_x_at
Hs.272897.2.S1_3p_x_at
ILMN_1742167
ILMN_1800261
TC12000363.hg
TC12001470.hg
TC12002866.hg
g13623540_3p_x_at
g5174476_3p_x_at
Participates
as a member of
Unfolded alpha/beta tubulin [cytosol] (Homo sapiens)
Other forms of this molecule
AcK-TUBA1B [cytosol]
Ac K40 TUBA1B [axonemal microtubule]
TUBA1B folding intermediate [cytosol]
L-isoglutamyl polyglycyl-TUBA1B [cytosol]
Polyglutamyl-TUBA1B [cytosol]
TUBA1B(1-450) [cytosol]
TUBA1B [axonemal microtubule]
TUBA1B [cytosol]
Cross References
RefSeq
NP_006073.2
OpenTargets
ENSG00000123416
HPA
ENSG00000123416-TUBA1B
GeneCards
P68363
Ensembl
ENST00000336023
,
ENSG00000123416
,
ENSP00000336799
PRO
P68363
Pharos - Targets
P68363
HMDB Protein
HMDBP08594
PDB
7LXB
,
7Z6S
,
5IJ9
,
6QUS
,
7SJ9
,
7SJ8
,
5IJ0
,
2E4H
,
7PJF
,
8VA2
,
6J4V
,
6J8O
,
8V2I
,
7SJ7
,
6QVJ
,
7M20
,
8VRK
,
6E7C
,
7ZCW
,
6E7B
,
6QVE
,
5N5N
,
8VRJ
,
6I2I
,
6QUY
,
6S8L
,
7M18
,
7SJA
,
8VT7
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15398 DLGAP5
1
DLGAP5 [cytosol]
(R-HSA-264452)
0.643
3
UniProt:P17987 TCP1
1
TCP1 [cytosol]
(R-HSA-390448)
0.643
4
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
UniProt:P37840 SNCA
5
SNCA A30P [cytosol]
(R-HSA-5658569)
SNCA [extracellular region]
(R-HSA-976954)
Ub-SNCA [cytosol]
(R-HSA-5660754)
p-S129-SNCA [cytosol]
(R-HSA-9836432)
SNCA [cytosol]
(R-HSA-5658500)
0.556
3
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.527
3
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
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