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MYO1C [cytosol]
Stable Identifier
R-HSA-1449619
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Myosin-Ic, MYO1C_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Myosin [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
RALA:GTP binds MYO1C:CALM1 and activates MYO1C (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
MYO1C:CALM1 [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
MYO1C:CALM1 [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
MYO1C:CALM1 [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
GGC-RALA:GTP:MYO1C:Exocyst [plasma membrane] (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
MYO1C:CALM1 [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
MYO1C [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O00159 MYO1C
Gene Names
MYO1C
Chain
chain:1-1063
Reference Genes
BioGPS Gene:4641 MYO1C
COSMIC (genes):MYO1C MYO1C
CTD Gene:4641 MYO1C
dbSNP Gene:4641 MYO1C
ENSEMBL:ENSG00000197879 MYO1C
HGNC:7597 MYO1C
KEGG Gene (Homo sapiens):4641 MYO1C
Monarch:4641 MYO1C
NCBI Gene:4641 MYO1C
OMIM:606538 MYO1C
UCSC:O00159 MYO1C
Reference Transcript
RefSeq:NM_033375.4 MYO1C
RefSeq:NM_001080779.1 MYO1C
RefSeq:NM_001080950.1 MYO1C
Other Identifiers
11716452_a_at
11716453_s_at
11716454_x_at
11737769_a_at
11748995_a_at
16839352
214656_3p_x_at
214656_x_at
225080_at
32811_3p_at
32811_at
3740166
3740202
3740203
3740204
3740205
3740208
3740209
3740210
3740212
3740214
3740215
3740216
3740218
3740220
3740222
3740223
3740224
3740225
3740226
3740227
3740229
3740230
3740232
3740233
3740234
3740235
3740236
3740237
3740238
3740239
3740240
3740241
3740242
3740243
3740244
3740245
3740248
3740249
3740250
3740251
3740252
3740263
4641
64098_at
65556_at
8011027
A_23_P164022
A_23_P416656
GE85652
GO:0000146
GO:0000166
GO:0001726
GO:0002376
GO:0003674
GO:0003774
GO:0003779
GO:0005102
GO:0005515
GO:0005516
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005635
GO:0005643
GO:0005654
GO:0005730
GO:0005737
GO:0005829
GO:0005856
GO:0005886
GO:0005902
GO:0005903
GO:0006605
GO:0006612
GO:0006810
GO:0006950
GO:0007010
GO:0007015
GO:0007165
GO:0008022
GO:0008092
GO:0008150
GO:0009925
GO:0015031
GO:0015629
GO:0016020
GO:0016192
GO:0016328
GO:0016459
GO:0016461
GO:0016604
GO:0016887
GO:0017160
GO:0019899
GO:0022607
GO:0030050
GO:0030335
GO:0030659
GO:0030705
GO:0030838
GO:0030898
GO:0031410
GO:0031941
GO:0031982
GO:0032420
GO:0032421
GO:0032587
GO:0032991
GO:0034330
GO:0038089
GO:0038096
GO:0040011
GO:0042995
GO:0043167
GO:0043226
GO:0045121
GO:0045335
GO:0045815
GO:0048870
GO:0051015
GO:0051028
GO:0060171
GO:0065003
GO:0070062
GO:0071346
GO:0090314
GO:1900078
GO:1900748
GO:2000810
Hs.286226.0.A1_3p_s_at
Hs.297939.4.A1_3p_at
ILMN_1812616
ILMN_2250820
ILMN_2329165
PH_hs_0014804
TC17000974.hg
X98507_at
Participant Of
hasComponent
MYO1C:CALM1 [cytosol]
hasMember
Myosin [cytosol]
Inferred To
myo1c [cytosol] (Xenopus tropicalis)
myoG [cytosol] (Dictyostelium discoideum)
Homologues of MYO1C [cytosol] (Dictyostelium discoideum)
myoF [cytosol] (Dictyostelium discoideum)
Myo61F [cytosol] (Drosophila melanogaster)
myo1cb [cytosol] (Danio rerio)
MYO1C [cytosol] (Canis familiaris)
MYO1C [cytosol] (Gallus gallus)
MYO1C [cytosol] (Sus scrofa)
Myo1c [cytosol] (Mus musculus)
Myo1c [cytosol] (Rattus norvegicus)
myoE [cytosol] (Dictyostelium discoideum)
Cross References
RefSeq
NP_001074248.1
,
NP_001074419.1
,
NP_203693.3
OpenTargets
ENSG00000197879
GeneCards
O00159
HPA
ENSG00000197879-MYO1C
Ensembl
ENST00000575158
,
ENSP00000459271
,
ENST00000648651
,
ENST00000570984
,
ENSP00000459174
,
ENST00000646049
,
ENSP00000354283
,
ENSG00000197879
,
ENST00000648446
,
ENST00000361007
,
ENSP00000496954
,
ENSP00000496799
,
ENSP00000493973
PRO
O00159
Orphanet
22978
PDB
4BYF
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:P03372 ESR1
8
SUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.462
2
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