ZC3HAV1(2-624)-p-BRAF(439-766) fusion [cytosol]

Stable Identifier
R-HSA-6802557
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
25204415 The landscape of kinase fusions in cancer

Kim, JL, Schalm, S, Stransky, N, Lengauer, C, Cerami, E

Nat Commun 2014
External Reference Information
External Reference
Gene Names
ZC3HAV1, ZC3HDC2, PRO1677
Chain
initiator methionine:, chain:2-902
Other Identifiers
11717366_at
11717367_at
11717368_x_at
11756839_x_at
17063428
213051_PM_at
213051_at
220104_PM_at
220104_at
225634_PM_at
225634_at
2995180
3075567
3075568
3075569
3075570
3075572
3075573
3075575
3075576
3075577
3075583
3075584
3075588
3075589
3075590
3075592
3075593
3075594
3075597
3075598
3075599
3075600
3075601
3075609
3075610
35682_at
56525_at
56829
69142_at
8143279
A_23_P20122
A_23_P425224
A_24_P341938
A_33_P3397418
GE82494
GE88728
GO:0002376
GO:0003723
GO:0003824
GO:0003950
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0009615
GO:0016071
GO:0016740
GO:0023052
GO:0032481
GO:0032727
GO:0032728
GO:0043123
GO:0043226
GO:0045071
GO:0045087
GO:0045296
GO:0046872
GO:0051607
GO:0061014
GO:0098542
GO:1900246
HMNXSV003015407
HMNXSV003024895
Hs.325568.0.A1_3p_at
Hs.35254.1.S1_3p_at
ILMN_1667068
ILMN_1724837
ILMN_1729973
PH_hs_0022101
TC07001910.hg
g9910221_3p_at
Participates
Other forms of this molecule
Modified Residues
Name
Insertion of residues 439 to 766 at 625 from UniProt:P15056 BRAF
Coordinate
625
Name
O-phospho-L-serine at 446
Coordinate
446
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 729
Coordinate
729
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 599
Coordinate
599
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 602
Coordinate
602
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Disease
Name Identifier Synonyms
thyroid carcinoma DOID:3963 head and neck cancer, Thyroid
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P67809 YBX1  5 0.564 4
 UniProt:Q9NQT4 EXOSC5  2 0.536 2
 UniProt:P03372 ESR1  10 0.527 3
 UniProt:Q15646 OASL  1 0.527 2
 UniProt:Q9H9Z2 LIN28A  1 0.527 3
 UniProt:O95786 RIGI  4 0.524 3
 UniProt:Q9NR30 DDX21  1 0.483 2
 UniProt:P13569 CFTR  17 0.483 8
 UniProt:Q8WYQ5 DGCR8  1 0.483 3
 UniProt:Q12906 ILF3  3 0.483 2
 UniProt:P62753 RPS6  4 0.483 4
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