EIF4G1 [cytosol]

Stable Identifier
R-HSA-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
eIF4G, eIF-4-gamma, eIF-4G, eukaryotic translation initiation factor 4 gamma, P220, Eukaryotic translation initiation factor 4 gamma, p220
Icon
EIF4G1 [cytosol] icon
EIF4G1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q04637 EIF4G1
Gene Names
EIF4G1, EIF4F, EIF4G, EIF4GI
Chain
chain:1-1599
Reference Genes
BioGPS Gene:1981 EIF4G1
COSMIC (genes):EIF4G1 EIF4G1
CTD Gene:1981 EIF4G1
dbSNP Gene:1981 EIF4G1
ENSEMBL:ENSG00000114867 EIF4G1
HGNC:3296 EIF4G1
KEGG Gene (Homo sapiens):1981 EIF4G1
Monarch:1981 EIF4G1
NCBI Gene:1981 EIF4G1
OMIM:600495 EIF4G1
UCSC:Q04637 EIF4G1
Reference Transcript
Other Identifiers
0000770164
0001190551
0005390035
11726566_a_at
11726567_a_at
11726568_x_at
1306_at
14774
16948909
1981
1LJ2
1UG3
208624_s_at
208625_3p_s_at
208625_s_at
2655689
2655690
2655691
2655692
2655693
2655695
2655696
2655697
2655698
2655699
2655700
2655701
2655702
2655704
2655705
2655706
2655707
2655708
2655709
2655711
2655712
2655713
2655714
2655715
2655716
2655717
2655718
2655719
2655720
2655721
2655722
2655723
2655725
2655727
2655728
2655729
2655730
2655731
2655732
2655733
2655734
2655735
2655737
2655738
2655739
2655741
2655743
2655745
2655747
2655750
2655751
2655752
2655753
2655754
2655756
28487
2W97
32844_at
43866
4AZA
4F02
57332_r_at
5EHC
5EI3
5EIR
5T46
69222_at
8084439
A_23_P218892
AAC78443
AAC78444
AAC82471
AAL92872
AAM69365
AC078797
AF002816
AF004836
AF104913
AF281070
AJ001046
AK131407
AY082886
BAA02185
BAD18554
BX647812
C9J2Z7
C9J556
C9J6B6
C9J987
C9JF13
C9JHW9
C9JIH5
C9JSU8
C9JWH7
C9JWH9
C9JWW9
C9K073
CAA04500
CAB014774
CAI46013
CCDS3259
CCDS3260
CCDS3261
CCDS46970
CCDS54687
CCDS54688
CCDS77866
CH471052
D12686
E7EUU4
E7EX73
E9PGM1
EAW78257
EAW78259
EAW78262
EAW78263
EAW78264
EAW78265
EAW78266
EAW78267
EIF4G1
EIF4G1-201
EIF4G1-202
EIF4G1-203
EIF4G1-204
EIF4G1-205
EIF4G1-206
EIF4G1-209
EIF4G1-212
EIF4G1-218
EIF4G1-219
ENSG00000114867
ENSP00000316879
ENSP00000317600
ENSP00000338020
ENSP00000343450
ENSP00000371767
ENSP00000376320
ENSP00000391935
ENSP00000404754
ENSP00000411826
ENSP00000416255
ENST00000342981
ENST00000342981.8
ENST00000346169
ENST00000346169.6
ENST00000350481
ENST00000350481.9
ENST00000352767
ENST00000352767.7
ENST00000382330
ENST00000382330.7
ENST00000392537
ENST00000392537.6
ENST00000414031
ENST00000414031.5
ENST00000424196
ENST00000424196.5
ENST00000434061
ENST00000434061.6
ENST00000435046
ENST00000435046.6
EntrezGene:1981
EntrezGene:EIF4G1
F8WB97
F8WCF2
g3941723_3p_s_at
GE62301
GO:0000184
GO:0000278
GO:0001662
GO:0002191
GO:0003674
GO:0003723
GO:0003729
GO:0003743
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005844
GO:0006412
GO:0006413
GO:0006417
GO:0006446
GO:0006464
GO:0006914
GO:0006950
GO:0007049
GO:0008135
GO:0008150
GO:0008190
GO:0008219
GO:0009056
GO:0009058
GO:0010507
GO:0010801
GO:0010942
GO:0016020
GO:0016032
GO:0016281
GO:0022607
GO:0030154
GO:0030307
GO:0031369
GO:0031669
GO:0032270
GO:0032502
GO:0032991
GO:0033138
GO:0034641
GO:0034645
GO:0034655
GO:0040007
GO:0042592
GO:0042802
GO:0043167
GO:0043226
GO:0043488
GO:0044403
GO:0045666
GO:0048856
GO:0060090
GO:0060964
GO:0065003
GO:0080135
GO:0097009
GO:1900087
GO:1901215
GO:1905537
GO:1905606
GO:1905612
GO:1905618
GO:1905696
HGNC:3296
HPA028487
HPA043866
Hs.211568.1.A1_3p_a_at
ILMN_1657066
ILMN_1672902
ILMN_1678244
ILMN_1768470
ILMN_2370772
IPR003307
IPR003890
IPR003891
IPR016021
IPR016024
IPR037584
MIM:600495
MIM:614251
NM_001194946
NM_001194947
NM_001291157
NM_004953
NM_182917
NM_198241
NM_198242
NM_198244
NP_001181875
NP_001181876
NP_001278086
NP_004944
NP_886553
NP_937884
NP_937885
NP_937887
PF02020
PF02847
PF02854
PH_hs_0030188
SM00515
SM00543
SM00544
TC03001000.hg
TC03002693.hg
UPI000014054E
UPI000021BFAD
UPI000021BFAF
UPI00003671E5
UPI00003671E6
UPI0000E5AB2D
UPI00015E0966
UPI000198CBA8
Participant Of
hasComponent
input
output
hasMember
Other forms of this molecule
p-S1108,S1148,S1192-EIF4G1 [cytosol]
Inferred To
EIF4G1 [cytosol] (Bos taurus)
EIF4G1 [cytosol] (Caenorhabditis elegans)
EIF4G1 [cytosol] (Canis familiaris)
EIF4G1 [cytosol] (Danio rerio)
EIF4G1 [cytosol] (Dictyostelium discoideum)
EIF4G1 [cytosol] (Drosophila melanogaster)
EIF4G1 [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Mus musculus)
EIF4G1 [cytosol] (Plasmodium falciparum)
EIF4G1 [cytosol] (Rattus norvegicus)
EIF4G1 [cytosol] (Saccharomyces cerevisiae)
EIF4G1 [cytosol] (Schizosaccharomyces pombe)
EIF4G1 [cytosol] (Sus scrofa)
EIF4G1 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (16)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P60842 EIF4A1  1 0.961 15
 UniProt:P06730 EIF4E  1 0.883 9
 UniProt:P11940 PABPC1  1 0.835 6
 UniProt:Q14240 EIF4A2  1 0.656 4
 UniProt:Q9BWF3-1 RBM4      0.591 4
 UniProt:Q9UGR2 Z3H7B      0.567 3
 UniProt:P23116  1 0.564 2
 UniProt:O00571 DDX3X  3 0.557 3
 UniProt:Q04637 EIF4G1  2 0.544 2
 UniProt:P03372 ESR1  8 0.527 3
 UniProt:O75822 EIF3J  1 0.524 2
 UniProt:Q9J0X9 Q9J0X9      0.499 3
 UniProt:Q14103-4 HNRNPD  2 0.499 3
 UniProt:Q13283 G3BP1      0.491 2
 UniProt:Q00721 NSP3      0.482 2
 UniProt:Q09161 NCBP1  2 0.462 2