EIF4G1 [cytosol]

Stable Identifier
R-HSA-72584
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
eIF4G, eIF-4-gamma, eIF-4G, eukaryotic translation initiation factor 4 gamma, P220, Eukaryotic translation initiation factor 4 gamma, p220
Icon
EIF4G1 [cytosol] icon
EIF4G1 [cytosol] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q04637 EIF4G1
Gene Names
EIF4G1, EIF4F, EIF4G, EIF4GI
Chain
initiator methionine:, chain:1-1599
Reference Genes
BioGPS Gene:1981 EIF4G1
COSMIC (genes):EIF4G1 EIF4G1
CTD Gene:1981 EIF4G1
dbSNP Gene:1981 EIF4G1
ENSEMBL:ENSG00000114867 EIF4G1
ENSEMBL_homo_sapiens_GENE:ENSG00000114867.22 EIF4G1
HGNC:3296 EIF4G1
KEGG Gene (Homo sapiens):1981 EIF4G1
Monarch:1981 EIF4G1
NCBI Gene:1981 EIF4G1
OMIM:600495 EIF4G1
UCSC:Q04637 EIF4G1
Reference Transcript
Other Identifiers
11726566_a_at
11726567_a_at
11726568_x_at
1306_at
16948909
1981
208624_PM_s_at
208624_s_at
208625_3p_s_at
208625_PM_s_at
208625_s_at
2655689
2655690
2655691
2655692
2655693
2655695
2655696
2655697
2655698
2655699
2655700
2655701
2655702
2655704
2655705
2655706
2655707
2655708
2655709
2655711
2655712
2655713
2655714
2655715
2655716
2655717
2655718
2655719
2655720
2655721
2655722
2655723
2655725
2655727
2655728
2655729
2655730
2655731
2655732
2655733
2655734
2655735
2655737
2655738
2655739
2655741
2655743
2655745
2655747
2655750
2655751
2655752
2655753
2655754
2655756
32844_at
57332_r_at
69222_at
8084439
A_23_P218892
GE62301
GO:0000278
GO:0001662
GO:0002181
GO:0002191
GO:0003723
GO:0003729
GO:0003743
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005840
GO:0006412
GO:0006413
GO:0006417
GO:0006446
GO:0006914
GO:0008135
GO:0008190
GO:0009059
GO:0010494
GO:0010507
GO:0010801
GO:0016020
GO:0016281
GO:0030154
GO:0030182
GO:0030307
GO:0030324
GO:0031047
GO:0031369
GO:0031669
GO:0033138
GO:0034330
GO:0035278
GO:0036211
GO:0036493
GO:0042802
GO:0043226
GO:0045182
GO:0045471
GO:0045666
GO:0048856
GO:0051247
GO:0060090
GO:0065003
GO:0080135
GO:0097009
GO:0098794
GO:1900087
GO:1904377
GO:1905537
GO:1905606
GO:1905612
HMNXSV003026478
Hs.211568.1.A1_3p_a_at
ILMN_1672902
ILMN_1678244
ILMN_1768470
ILMN_2370772
PH_hs_0030188
TC03001000.hg
TC03002693.hg
g3941723_3p_s_at
Participates
as a component of
as an input of
as an output of
as a member of
Other forms of this molecule
p-S1108,S1148,S1192-EIF4G1 [cytosol]
Inferred To
TIF4631 [cytosol] (Saccharomyces cerevisiae)
Eif4g1 [cytosol] (Mus musculus)
Eif4g1 [cytosol] (Rattus norvegicus)
eIF4G1 [cytosol] (Drosophila melanogaster)
Homologues of EIF4G1 [cytosol] (Drosophila melanogaster)
Homologues of EIF4G1 [cytosol] (Plasmodium falciparum)
Ghost homologue of EIF4G1 [cytosol] (Danio rerio)
ifg-1 [cytosol] (Caenorhabditis elegans)
eif4g1 [cytosol] (Xenopus tropicalis)
tif471 [cytosol] (Schizosaccharomyces pombe)
eIF4G2 [cytosol] (Drosophila melanogaster)
eif4g [cytosol] (Dictyostelium discoideum)
EIF4G1 [cytosol] (Bos taurus)
EIF4G1 [cytosol] (Canis familiaris)
EIF4G1 [cytosol] (Gallus gallus)
EIF4G1 [cytosol] (Plasmodium falciparum)
EIF4G1 [cytosol] (Sus scrofa)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (21)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P60842 EIF4A1  1 0.964 17
 UniProt:P06730 EIF4E  1 0.924 13
 UniProt:P11940 PABPC1  1 0.835 6
 UniProt:Q14240 EIF4A2  1 0.656 4
 UniProt:Q9BWF3-1 RBM4      0.591 4
 UniProt:Q9UGR2 Z3H7B      0.567 3
 UniProt:P55884 EIF3B  1 0.564 2
 UniProt:P23116  1 0.564 2
 UniProt:Q9BUB5 MKNK1  1 0.564 3
 UniProt:O00571 DDX3X  3 0.557 3
 UniProt:Q06787 FMR1      0.527 2
 UniProt:Q13112 CAF1B      0.527 2
 UniProt:P10636-8 MAPT  3 0.527 4
 UniProt:P03372 ESR1  8 0.527 3
 UniProt:O75822 EIF3J  1 0.524 2
 UniProt:Q9J0X9 Q9J0X9      0.499 3
 UniProt:Q14103-4 HNRNPD  2 0.499 3
 UniProt:Q13283 G3BP1  1 0.491 2
 UniProt:P13569 CFTR  17 0.483 7
 UniProt:Q00721 NSP3      0.482 2
 UniProt:Q09161 NCBP1  2 0.462 2
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