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SP3 [nucleoplasm]
Stable Identifier
R-HSA-2160951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transcription factor Sp3
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of transcription factors (Homo sapiens)
PIAS1 SUMOylates SP3 with SUMO1 (Homo sapiens)
SP3 [nucleoplasm] (Homo sapiens)
PIAS1 SUMOylates SP3 with SUMO2 (Homo sapiens)
SP3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q02447 SP3
Gene Names
SP3
Chain
chain:1-781
Reference Genes
BioGPS Gene:6670 SP3
COSMIC (genes):SP3 SP3
CTD Gene:6670 SP3
dbSNP Gene:6670 SP3
ENSEMBL:ENSG00000172845 SP3
ENSEMBL_homo_sapiens_GENE:ENSG00000172845.18 SP3
HGNC:11208 SP3
KEGG Gene (Homo sapiens):6670 SP3
Monarch:6670 SP3
NCBI Gene:6670 SP3
OMIM:601804 SP3
UCSC:Q02447 SP3
Reference Transcript
RefSeq:NM_001172712.1 SP3
RefSeq:NM_003111.4 SP3
RefSeq:NM_001017371.4 SP3
Other Identifiers
11723294_x_at
11731618_a_at
11731619_x_at
11758883_at
11759066_at
11761980_a_at
16905163
213168_PM_at
213168_at
229217_PM_at
229217_at
232709_PM_at
232709_at
238035_PM_at
238035_at
2587523
2587524
2587525
2587526
2587527
2587530
2587531
2587533
2587534
2587548
2587553
2587554
2587555
2587556
2587557
2587558
2587591
2587592
2587608
2587610
2587612
3520184
41573_at
42046_at
6670
8056798
81493_at
90572_at
A_23_P347198
A_24_P58283
A_32_P20240
GE59947
GE903009
GO:0000122
GO:0000785
GO:0000977
GO:0000978
GO:0000981
GO:0000987
GO:0001227
GO:0001503
GO:0001701
GO:0001779
GO:0001829
GO:0001889
GO:0001892
GO:0002318
GO:0002376
GO:0003677
GO:0003682
GO:0003690
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0016605
GO:0017053
GO:0022414
GO:0030154
GO:0030183
GO:0030217
GO:0030218
GO:0030219
GO:0030224
GO:0030324
GO:0030851
GO:0032993
GO:0043226
GO:0043353
GO:0045892
GO:0045893
GO:0045944
GO:0046872
GO:0048596
GO:0048706
GO:0048856
GO:0060136
GO:0060216
GO:0061629
GO:0140110
GO:1990837
HMNXSV003054035
Hs.120770.0.A1_3p_at
Hs.154295.0.A1_3p_at
Hs.154295.0.A1_3p_x_at
Hs.44450.1.A1_3p_at
Hs.88605.0.S1_3p_at
ILMN_1662168
ILMN_1691171
ILMN_1756942
ILMN_2389844
PH_hs_0004957
TC02002535.hg
TC02004696.hg
X68560_at
Participates
as an input of
PIAS1 SUMOylates SP3 with SUMO1 (Homo sapiens)
PIAS1 SUMOylates SP3 with SUMO2 (Homo sapiens)
Other forms of this molecule
monoSUMO1-K551-SP3 [nucleoplasm]
polySUMO2-K551-SP3 [nucleoplasm]
Inferred To
Sp3 [nucleoplasm]
(Mus musculus)
Sp3 [nucleoplasm]
(Rattus norvegicus)
Spps [nucleoplasm]
(Drosophila melanogaster)
CRZ1 [nucleoplasm]
(Saccharomyces cerevisiae)
SP3 [nucleoplasm]
(Bos taurus)
SP3 [nucleoplasm]
(Canis familiaris)
SP3 [nucleoplasm]
(Gallus gallus)
SP3 [nucleoplasm]
(Sus scrofa)
sp4 [nucleoplasm]
(Danio rerio)
Cross References
RefSeq
NP_001017371.3
,
NP_003102.1
,
NP_001166183.1
OpenTargets
ENSG00000172845
GeneCards
Q02447
HPA
ENSG00000172845-SP3
Ensembl
ENSP00000310301
,
ENST00000310015
,
ENSG00000172845
,
ENSP00000406140
,
ENST00000418194
PRO
Q02447
Pharos - Targets
Q02447
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.667
4
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.666
4
UniProt:Q6MZP7 LIN54
1
LIN54 [nucleoplasm]
(R-HSA-389103)
0.556
3
UniProt:Q96BD5 PHF21A
1
PHF21A [nucleoplasm]
(R-HSA-996754)
0.556
3
UniProt:P14678-2 SNRPB
0.556
3
UniProt:Q7Z3K3 POGZ
0.556
3
UniProt:Q96Q77 CIB3
0.556
3
UniProt:Q5MJ10 SPXN2
0.556
3
UniProt:Q06546 GABPA
1
GABPA [nucleoplasm]
(R-HSA-1592206)
0.544
2
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