Reactome | PPP5C [cytosol]

PPP5C

Stable Identifier

R-HSA-5675402

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P53041 PPP5C

Gene Names

PPP5C, PPP5

Chain

initiator methionine:1, chain:2-499

Reference Genes

BioGPS Gene:5536 PPP5C

COSMIC (genes):PPP5C PPP5C

CTD Gene:5536 PPP5C

dbSNP Gene:5536 PPP5C

ENSEMBL:ENSG00000011485 PPP5C

HGNC:9322 PPP5C

KEGG Gene (Homo sapiens):hsa:5536 PPP5C

Monarch:5536 PPP5C

NCBI Gene:5536 PPP5C

OMIM:600658 PPP5C

UCSC:P53041 PPP5C

Reference Transcript

RefSeq:NM_006247.3 PPP5C

Other Identifiers

0002470707

04660+3.1.3.16

11718622_x_at

11745533_x_at

16863460

1A17

1S95

1WAO

201979_s_at

22641

29065

2BUG

3836762

3836763

3836764

3836772

3836774

3836779

3836781

3836784

3836786

3836787

3836789

3836790

3836791

3836794

3836795

3836796

3836797

3836798

3866044

391_at

392_g_at

3H60

3H61

3H62

3H63

3H64

3H66

3H67

3H68

3H69

4ZVZ

4ZX2

5536

56933

5HPE

8029814

A0A024R0Q7

A_23_P153583

CAB022641

CCDS12684

ENSG00000011485

ENSP00000012443

ENST00000012443

EntrezGene:5536

g5453957_3p_at

g5453957_3p_x_at

GE60120

GO:0000165

GO:0000278

GO:0001933

GO:0001965

GO:0003723

GO:0004721

GO:0004722

GO:0004871

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006281

GO:0006351

GO:0006470

GO:0006974

GO:0008017

GO:0008289

GO:0010288

GO:0016020

GO:0016576

GO:0016787

GO:0031072

GO:0042802

GO:0043005

GO:0043025

GO:0043123

GO:0043204

GO:0043231

GO:0043234

GO:0043278

GO:0043531

GO:0046872

GO:0051259

GO:0051291

GO:0051879

GO:0060548

GO:0070301

GO:0071276

GO:0071944

GO:1901215

GO:1990635

GO:2000324

HGNC:9322

HPA029065

HPA056933

Hs.654604

ILMN_1745332

MIM:600658

NM_001204284

NM_006247

NP_001191213

NP_006238

PF00149

PF00515

PF08321

PH_hs_0025229

PPP5C

PPP5C-201

PR00114

SM00028

SM00156

TC19000663.hg

uc002pem.4

UPI0000041859

X89416_at

XM_017026935

XP_016882424

Other forms of this molecule

PPP5C [nucleoplasm]

Inferred To

PPP5C [cytosol] (Bos taurus)

PPP5C [cytosol] (Caenorhabditis elegans)

PPP5C [cytosol] (Canis familiaris)

PPP5C [cytosol] (Danio rerio)

PPP5C [cytosol] (Dictyostelium discoideum)

PPP5C [cytosol] (Drosophila melanogaster)

PPP5C [cytosol] (Mus musculus)

PPP5C [cytosol] (Plasmodium falciparum)

PPP5C [cytosol] (Rattus norvegicus)

PPP5C [cytosol] (Sus scrofa)

PPP5C [cytosol] (Xenopus tropicalis)

Homologues of PPP5C [cytosol] (Danio rerio)

Cross References

RefSeq

NP_006238.1

Brenda

3.1.3.16

GeneCards

P53041

DOCK Blaster

3H61, 3H69, 4ZVZ, 5HPE, 1S95, 1WAO, 3H68, 3H67, 3H66, 3H64, 3H63, 3H60, 3H62, 4ZX2, 1A17

ZINC target

P53041

PRO

P53041

HMDB Protein

HMDBP08687

PDB

3H63, 3H69, 1WAO, 5UI1, 3H68, 3H62, 1S95, 3H67, 5HPE, 3H61, 1A17, 3H66, 4ZX2, 3H60, 4ZVZ, 3H64, 2BUG

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08238 HSP90AB1	5	HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399)	0.832	7
UniProt:P07900 HSP90AA1	7	HSP90AA1 [secretory granule lumen] (R-HSA-6801515) HSP90AA1 [endocytic vesicle lumen] (R-HSA-3221912) HSP90AA1 [extracellular region] (R-HSA-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-HSA-6801470) HSP90AA1 [plasma membrane] (R-HSA-534996) HSP90AA1 [nucleoplasm] (R-HSA-5082401) HSP90AA1 [cytosol] (R-HSA-192864)	0.794	11
UniProt:Q16543 CDC37	1	CDC37 [cytosol] (R-HSA-1221609)	0.708	5
UniProt:P03372 ESR1	3	ESR1 [nucleoplasm] (R-HSA-446168) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210) ESR1 [cytosol] (R-HSA-9020968)	0.625	4
UniProt:P31948 STIP1	1	STIP1 [cytosol] (R-HSA-443857)	0.623	4
UniProt:O14654 IRS4	2	IRS4 [plasma membrane] (R-HSA-2424297) p-Y-IRS4 [plasma membrane] (R-HSA-2424302)	0.597	3
UniProt:P50750 CDK9	1	CDK9 [nucleoplasm] (R-HSA-51801)	0.558	3
UniProt:Q9UHD1 CHRD1			0.547	2
UniProt:Q15185 PTGES3	2	PTGES3 [nucleoplasm] (R-HSA-5082403) PTGES3 [cytosol] (R-HSA-265269)	0.527	2
UniProt:P30153 PPP2R1A	2	PPP2R1A [cytosol] (R-HSA-165982) PPP2R1A [nucleoplasm] (R-HSA-165968)	0.524	3
UniProt:Q92731 ESR2	2	ESR2 [cytosol] (R-HSA-9020970) ESR2 [nucleoplasm] (R-HSA-446165)	0.508	4
UniProt:Q5SY16 NOL9	1	NOL9 [nucleoplasm] (R-HSA-6791216)	0.499	2
UniProt:Q9UL18 AGO1	2	EIF2C1 [cytosol] (R-HSA-210616) EIF2C1 [nucleoplasm] (R-HSA-5578686)	0.499	2
UniProt:Q9H9G7 AGO3	1	EIF2C3 [cytosol] (R-HSA-210615)	0.499	2
UniProt:P53041 PPP5C	2	PPP5C [nucleoplasm] (R-HSA-5683410) PPP5C [cytosol] (R-HSA-5675402)	0.499	2
UniProt:Q49AN0 CRY2	4	p-S-CRY2 [nucleoplasm] (R-HSA-400328) p-S-CRY2 [cytosol] (R-HSA-400305) CRY2 [cytosol] (R-HSA-400255) Ub-p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.499	3
UniProt:Q58FG0 HS905			0.462	2
UniProt:P27708 CAD	1	CAD [cytosol] (R-HSA-73452)	0.462	2
UniProt:Q9Y266 NUDC	3	NUDC [nucleoplasm] (R-HSA-156716) p-S274,S326-NUDC [nucleoplasm] (R-HSA-156702) NUDC [cytosol] (R-HSA-377731)	0.462	2