Reactome | EIF4G3 [cytosol]

EIF4G3 [cytosol]

Stable Identifier

R-HSA-1678827

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Eukaryotic translation initiation factor 4 gamma 3, IF4G3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43432 EIF4G3

Gene Names

EIF4G3

Chain

chain:1-1585

Reference Genes

BioGPS Gene:8672 EIF4G3

COSMIC - genes:EIF4G3 EIF4G3

CTD Gene:8672 EIF4G3

dbSNP Gene:8672 EIF4G3

ENSEMBL:ENSG00000075151 EIF4G3

HGNC:3298 EIF4G3

KEGG:hsa:8672 EIF4G3

Monarch:8672 EIF4G3

NCBI Gene:8672 EIF4G3

OMIM:603929 EIF4G3

UCSC:O43432 EIF4G3

Reference Transcript

Participates

as a member of

EIF4G [cytosol] (Homo sapiens)

Inferred To

EIF4G3 [cytosol] (Bos taurus)

EIF4G3 [cytosol] (Canis familiaris)

EIF4G3 [cytosol] (Sus scrofa)

ifg-1 [cytosol] (Caenorhabditis elegans)

Eif4g3 [cytosol] (Mus musculus)

eif4g [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

XP_054195359.1, NP_001185732.1, NP_001424543.1, NP_001185731.1, NP_001378821.1, XP_047289275.1, NP_003751.2, NP_001378822.1, NP_001185730.1, XP_047289268.1, NP_001378823.1

OpenTargets

ENSG00000075151

ENSEMBL

ENSP00000364071, ENST00000686579, ENST00000356916, ENSG00000075151, ENSP00000509941, ENST00000264211, ENST00000374935, ENST00000682284, ENSP00000349386, ENSP00000264211, ENSP00000507819

HPA

ENSG00000075151-EIF4G3

GeneCards

EIF4G3

PRO

O43432

Pharos - Targets

O43432

GlyGen

O43432

PDB

1HU3

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06730 EIF4E	1	EIF4E [cytosol] (R-HSA-72578)	0.813	7
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.544	2
UniProt:P21709 EPHA1	2	p-Y599,Y605-EPHA1 [plasma membrane] (R-HSA-3928336) EPHA1 [plasma membrane] (R-HSA-211415)	0.527	2
UniProt:Q15274 QPRT	1	QPRT [cytosol] (R-HSA-197212)	0.527	2
UniProt:P03372 ESR1	10	ESR1 [cytosol] (R-HSA-9020968) ESR1 [nucleoplasm] (R-HSA-446168) Me260-ESR1 [cytosol] (R-HSA-9632177) Me260-PalmS-ESR1 [plasma membrane] (R-HSA-9637788) PalmS-ESR1 [plasma membrane] (R-HSA-9021057) PalmS-ESR1 [cytosol] (R-HSA-9020974) p-S167-ESR1 [cytosol] (R-HSA-9841254) p-S167-ESR1 [nucleoplasm] (R-HSA-9841867) monoSUMO1-5K-ESR1 [nucleoplasm] (R-HSA-4090302) p-S118-ESR1 [nucleoplasm] (R-HSA-9024210)	0.527	3
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.483	3

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