Reactome | EDC3 [cytosol]

EDC3 [cytosol]

Stable Identifier

R-HSA-429997

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Enhancer of mRNA-decapping protein 3, EDC3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96F86 EDC3

Gene Names

EDC3, LSM16, YJDC, YJEFN2, PP844

Chain

chain:1-508

Reference Genes

BioGPS Gene:80153 EDC3

COSMIC (genes):EDC3 EDC3

CTD Gene:80153 EDC3

dbSNP Gene:80153 EDC3

ENSEMBL:ENSG00000179151 EDC3

HGNC:26114 EDC3

KEGG:hsa:80153 EDC3

Monarch:80153 EDC3

NCBI Gene:80153 EDC3

OMIM:609842 EDC3

UCSC:Q96F86 EDC3

Reference Transcript

Other Identifiers

11719935_a_at

11719936_a_at

16811672

219207_PM_at

219207_at

226042_PM_at

226042_at

3633049

3633050

3633051

3633052

3633053

3633054

3633056

3633057

3633058

3633059

3633062

3633063

3633064

3633066

3633067

3633071

3633072

3633073

3633074

3633075

3633077

3633078

3633079

3633080

43416_s_at

54839_at

56298_at

7990379

80153

A_23_P21155

A_24_P338992

A_32_P223644

GE56616

GE84986

GO:0000932

GO:0003723

GO:0003729

GO:0005515

GO:0005737

GO:0005829

GO:0016020

GO:0016071

GO:0031087

GO:0033962

GO:0036464

GO:0042802

GO:0043226

HMNXSV003024070

Hs.22208.0.S1_3p_at

ILMN_1724581

PH_hs_0022396

TC15001646.hg

g13376637_3p_at

Participates

as a component of

DCP1-DCP2 Decapping Complex [cytosol] (Homo sapiens)

Inferred To

edc3 [cytosol] (Danio rerio)

edc3 [cytosol] (Xenopus tropicalis)

edc-3 [cytosol] (Caenorhabditis elegans)

EDC3 [cytosol] (Bos taurus)

EDC3 [cytosol] (Canis familiaris)

EDC3 [cytosol] (Gallus gallus)

EDC3 [cytosol] (Saccharomyces cerevisiae)

EDC3 [cytosol] (Sus scrofa)

Ghost homologue of EDC3 [cytosol] (Dictyostelium discoideum)

Ghost homologue of EDC3 [cytosol] (Plasmodium falciparum)

Edc3 [cytosol] (Drosophila melanogaster)

Edc3 [cytosol] (Mus musculus)

Edc3 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_079359.2, NP_001135916.1, NP_001135915.1

OpenTargets

ENSG00000179151

ENSEMBL

ENSP00000455580, ENST00000426797, ENST00000315127, ENST00000568176, ENSP00000401343, ENST00000647659, ENSP00000497737, ENSP00000320503

HPA

ENSG00000179151-EDC3

PRO

Q96F86

Pharos - Targets

Q96F86

Orphanet

EDC3

GlyGen

Q96F86

PDB

3D3J, 2WAY, 2WAX, 2VC8, 6S8S, 3D3K

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NPI6 DCP1A	1	DCP1A [cytosol] (R-HSA-430043)	0.947	19
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.806	7
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.749	4
UniProt:O95429 BAG4	3	BAG4 [cytosol] (R-HSA-5212670) BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853156) BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853157)	0.643	3
UniProt:O75928-2 PIAS2	1	PIAS2-2 [nucleoplasm] (R-HSA-2993779)	0.556	3
UniProt:P47897 QARS1	2	QARS [cytosol] (R-HSA-379615) QARS [mitochondrial matrix] (R-HSA-379592)	0.556	3
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.536	4
UniProt:Q9P031 CCDC59	1	CCDC59 [nucleoplasm] (R-HSA-5683813)	0.527	2
UniProt:P11309 PIM1	1	PIM1 [nucleoplasm] (R-HSA-3215094)	0.527	3
UniProt:P46109 CRKL	2	CRKL [cytosol] (R-HSA-354384) p-CRKL [cytosol] (R-HSA-9024730)	0.527	2
UniProt:Q13107 USP4	1	USP4 [cytosol] (R-HSA-5212663)	0.527	2
UniProt:P26651 ZFP36	2	p-S60,S186-ZFP36 [cytosol] (R-HSA-450496) ZFP36 [cytosol] (R-HSA-450562)	0.499	2
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.483	4

Cite Us!