Reactome | Sfn [cytosol]

Sfn [cytosol]

Stable Identifier

R-RNO-1445105

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

SFN, G3V9A3

Locations in the PathwayBrowser

Expand all

Cell Cycle (Rattus norvegicus)

- Cell Cycle Checkpoints (Rattus norvegicus)
  - G2/M Checkpoints (Rattus norvegicus)
    - G2/M DNA damage checkpoint (Rattus norvegicus)
      - Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Rattus norvegicus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

Immune System (Rattus norvegicus)

- Cytokine Signaling in Immune system (Rattus norvegicus)
  - Interferon Signaling (Rattus norvegicus)
    - Antimicrobial mechanism of IFN-stimulated genes (Rattus norvegicus)
      - GBP-mediated host defense (Rattus norvegicus)
        
        Regulation of GBP-mediated host defense (Rattus norvegicus)
        
        SFN binds S-farn-C589,p-S156,T590-GBP1 (Rattus norvegicus)
        
        S-farn-C,p-S,T-GBP1:SFN dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

Programmed Cell Death (Rattus norvegicus)

- Apoptosis (Rattus norvegicus)
  - Intrinsic Pathway for Apoptosis (Rattus norvegicus)
    - Activation of BH3-only proteins (Rattus norvegicus)
      - Activation of BAD and translocation to mitochondria (Rattus norvegicus)
        
        Activation of BAD by calcineurin (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        Sequestration of BAD protein by 14-3-3 (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        14-3-3 proteins:p-S99-BAD complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

Signal Transduction (Rattus norvegicus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
  - Signaling by Rho GTPases (Rattus norvegicus)
    - RHO GTPase Effectors (Rattus norvegicus)
      - RHO GTPases activate PKNs (Rattus norvegicus)
        
        Association of p-S216-CDC25C with 14-3-3 proteins (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)
        
        p-S216-CDC25C:14-3-3 protein complex [cytosol] (Rattus norvegicus)
        
        14-3-3 dimer [cytosol] (Rattus norvegicus)
        
        SFN dimer [cytosol] (Rattus norvegicus)
        
        Sfn [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:G3V9A3

Gene Names

Sfn

Reference Genes

BioGPS Gene:313017 Sfn

ENSEMBL:ENSRNOG00000033153

KEGG:rno:313017 Sfn

Monarch:313017 Sfn

NCBI Gene:313017 Sfn

UCSC:G3V9A3 Sfn

Reference Transcript

RefSeq:NM_001416777.1 Sfn

Other Identifiers

10872572

1374806_at

17802702

313017

5690671

5841473

5897780

6031635

6087280

6383563

6390149

6444755

6475816

A_44_P958894

A_64_P006354

GO:0000122

GO:0003334

GO:0005634

GO:0005737

GO:0006355

GO:0006611

GO:0006886

GO:0006913

GO:0010482

GO:0010839

GO:0019901

GO:0030154

GO:0030216

GO:0030307

GO:0031424

GO:0043588

GO:0043616

GO:0045606

GO:0046827

GO:0048856

GO:0051219

GO:0051726

GO:0061436

GO:0072089

GO:0141156

GO:2000647

ILMN_1352207

PH_rn_0023815

Participates

as an input of

SFN dimerizes (Rattus norvegicus)

as a component of

SFN dimer [cytosol] (Rattus norvegicus)

Inferred From

SFN [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001403706.1

ENSEMBL

ENSRNOT00000043959, ENSRNOP00000040819, ENSRNOG00000033153

GlyGen

G3V9A3

RGD

1304729

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