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p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane]
Stable Identifier
R-HSA-1445101
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasmic vesicle membrane
Synonyms
p-6S-TBC1D4, p-5S-T642-AS160, p-5S-T642-TBC1D4, Phosphorylated TBC1D4, TBC1 domain family member 4, TBCD4_HUMAN, TBC1D4
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
14-3-3 binds p-5S,T642-AS160 (TBC1D4) (Homo sapiens)
p-5S,T642-AS160:14-3-3:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
Phospho AS160:14-3-3 [cytoplasmic vesicle membrane] (Homo sapiens)
p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane] (Homo sapiens)
p-5S,T642-AS160:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane] (Homo sapiens)
p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) (Homo sapiens)
p-5S,T642-AS160:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
p-5S,T642-TBC1D4 [cytoplasmic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60343 TBC1D4
Gene Names
TBC1D4, AS160, KIAA0603
Chain
chain:1-1298
Reference Genes
BioGPS Gene:9882 TBC1D4
COSMIC (genes):TBC1D4 TBC1D4
CTD Gene:9882 TBC1D4
dbSNP Gene:9882 TBC1D4
ENSEMBL:ENSG00000136111 TBC1D4
ENSEMBL_homo_sapiens_GENE:ENSG00000136111.14 TBC1D4
HGNC:19165 TBC1D4
KEGG Gene (Homo sapiens):9882 TBC1D4
Monarch:9882 TBC1D4
NCBI Gene:9882 TBC1D4
OMIM:612465 TBC1D4
UCSC:O60343 TBC1D4
Reference Transcript
RefSeq:NM_001286658.2 TBC1D4
RefSeq:NM_014832.4 TBC1D4
RefSeq:NM_001286659.2 TBC1D4
Other Identifiers
11731503_at
11746744_a_at
16779792
203386_PM_at
203386_at
203387_PM_s_at
203387_s_at
34672_at
3518087
3518088
3518089
3518090
3518091
3518092
3518093
3518094
3518097
3518100
3518105
3518109
3518110
3518112
3518113
3518115
3518116
3518117
3518118
3518119
3518120
3518121
3518123
3518124
3518125
3518126
3518127
3518128
3518154
3518155
3518156
3518157
3518158
63390_at
7972021
9882
A_23_P88095
GE53304
GO:0005096
GO:0005515
GO:0005737
GO:0005829
GO:0016192
GO:0031339
GO:0031982
GO:0032869
GO:0043226
GO:0061024
GO:0098772
HMNXSV003029558
Hs.173802.0.S2_3p_at
ILMN_1688098
PH_hs_0035645
TC13000738.hg
g7662197_3p_a_at
Participates
as a component of
Phospho AS160:14-3-3 [cytoplasmic vesicle membrane] (Homo sapiens)
p-5S,T642-AS160:IRAP [cytoplasmic vesicle membrane] (Homo sapiens)
Other forms of this molecule
TBC1D4 [cytoplasmic vesicle membrane]
Modified Residues
Name
O-phospho-L-serine at 318
Coordinate
318
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 341
Coordinate
341
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 570
Coordinate
570
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 588
Coordinate
588
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 642
Coordinate
642
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 751
Coordinate
751
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_055647.2
,
NP_001273587.1
,
NP_001273588.1
OpenTargets
ENSG00000136111
GeneCards
O60343
HPA
ENSG00000136111-TBC1D4
Ensembl
ENSP00000366852
,
ENST00000377636
,
ENST00000377625
,
ENST00000431480
,
ENSG00000136111
,
ENSP00000395986
,
ENSP00000366863
PRO
O60343
Pharos - Targets
O60343
PDB
7NIX
,
3QYB
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.792
5
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.706
5
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.695
6
UniProt:P31947 SFN
1
SFN [cytosol]
(R-HSA-1445105)
0.471
4
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