Reactome | MARK3 [cytosol]

MARK3 [cytosol]

Stable Identifier

R-HSA-5672591

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

CTAK1, EMK2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- MAPK family signaling cascades (Homo sapiens)
  - MAPK1/MAPK3 signaling (Homo sapiens)
    - RAF/MAP kinase cascade (Homo sapiens)
      - MAP2K and MAPK activation (Homo sapiens)
        
        Dissociation of RAS:RAF complex (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21RAS:GTP:activated RAF homo/heterodimers [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Dual mechanism MAP2K inhibitors bind MAP2Ks (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Dual mechanism MAPK inhibitors bind MAPKs (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        MAP2Ks phosphorylate MAPKs (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        RAF phosphorylates MAP2K dimer (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Single mechanism MAPK inhibitors bind phosphorylated MAPK (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Homo sapiens)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Homo sapiens)
        
        RAF/MAPK scaffolds [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
      - Negative regulation of MAPK pathway (Homo sapiens)
        
        BRAP binds KSR1:MARK3 (Homo sapiens)
        
        BRAP:KSR1:MARK3 [cytosol] (Homo sapiens)
        
        KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
      - RAF activation (Homo sapiens)
        
        MARK3 phosphorylates KSR1 (Homo sapiens)
        
        KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        PP2A dephosphorylates KSR1 (Homo sapiens)
        
        p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Phosphorylation of RAF (Homo sapiens)
        
        p21 RAS:GTP:activated RAF homo/heterodimer complexes [plasma membrane] (Homo sapiens)
        
        activated RAF/KSR1 [plasma membrane] (Homo sapiens)
        
        p-S311,T602 KSR1:MARK3 [plasma membrane] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        RAS:GTP:'activator' RAF homo/heterodimerizes with other RAF monomers (Homo sapiens)
        
        BRAP:KSR1:MARK3 [cytosol] (Homo sapiens)
        
        KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        Raf dimer inhibitors bind RAF heterodimers (Homo sapiens)
        
        p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p21RAS:GTP:homo/heterodimerized RAF complex:RAF dimer inhibitors [plasma membrane] (Homo sapiens)
        
        p21 RAS:GTP:homo/heterodimerized RAF complex [plasma membrane] (Homo sapiens)
        
        dephosphorylated "receiver" RAF/KSR1 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        YWHAB dimer dissociates from KSR1:MARK3 (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p-S311 KSR1:MARK3:YWHAB dimer [plasma membrane] (Homo sapiens)
        
        p-S311 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3 binds YWHAB dimer (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3:YWHAB dimer [cytosol] (Homo sapiens)
        
        p-S311,S406 KSR1:MARK3 [cytosol] (Homo sapiens)
        
        MARK3 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P27448 MARK3

Gene Names

MARK3, CTAK1, EMK2

Chain

chain:1-753

Reference Genes

BioGPS Gene:4140 MARK3

COSMIC (genes):MARK3 MARK3

CTD Gene:4140 MARK3

dbSNP Gene:4140 MARK3

ENSEMBL:ENSG00000075413 MARK3

ENSEMBL_homo_sapiens_GENE:ENSG00000075413.19 MARK3

HGNC:6897 MARK3

KEGG Gene (Homo sapiens):4140 MARK3

Monarch:4140 MARK3

NCBI Gene:4140 MARK3

OMIM:602678 MARK3

UCSC:P27448 MARK3

Reference Transcript

Other Identifiers

11725990_a_at

11738809_s_at

11740434_x_at

11754373_a_at

16789209

202568_PM_s_at

202568_s_at

202569_PM_s_at

202569_s_at

3553691

3553692

3553693

3553694

3553695

3553699

3553707

3553714

3553716

3553717

3553719

3553721

3553722

3553723

3553725

3553727

3553728

3553732

3553733

3553736

3553737

3553744

3553748

3553750

3553754

3553755

3553756

3553757

3553758

3553759

40826_at

4140

7977077

A_33_P3593546

GE58088

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005737

GO:0005829

GO:0005886

GO:0006468

GO:0008092

GO:0016020

GO:0016301

GO:0016310

GO:0016740

GO:0018105

GO:0023052

GO:0030425

GO:0032092

GO:0035331

GO:0035556

GO:0036211

GO:0036289

GO:0042995

GO:0043226

GO:0048156

GO:0050321

GO:0070062

GO:0106310

GO:0140096

GO:1900181

HMNXSV003007003

Hs.172766.0.S1_3p_s_at

ILMN_1704795

M80359_at

PH_hs_0025626

PH_hs_0033415

TC14000799.hg

g4505102_3p_a_at

Participates

as a component of

Inferred To

MARK3 [cytosol] (Bos taurus)

MARK3 [cytosol] (Caenorhabditis elegans)

MARK3 [cytosol] (Canis familiaris)

MARK3 [cytosol] (Dictyostelium discoideum)

MARK3 [cytosol] (Drosophila melanogaster)

MARK3 [cytosol] (Mus musculus)

MARK3 [cytosol] (Plasmodium falciparum)

MARK3 [cytosol] (Rattus norvegicus)

MARK3 [cytosol] (Sus scrofa)

Homologues of MARK3 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001122390.2, NP_001122392.2, NP_002367.5, NP_001122393.2, NP_001122391.2

ZINC - World Drugs

MARK3_HUMAN

Guide to Pharmacology - Targets

2099

OpenTargets

ENSG00000075413

ZINC - FDA approved

MARK3_HUMAN

ZINC - Substances

MARK3_HUMAN

ZINC target

P27448

ZINC - Biogenic

MARK3_HUMAN

PRO

P27448

PDB

3FE3, 2QNJ, 7P1L

ZINC - Investigational

MARK3_HUMAN

HPA

ENSG00000075413-MARK3

GeneCards

P27448

Ensembl

ENST00000440884, ENST00000553942, ENST00000416682, ENSG00000075413, ENSP00000402104, ENSP00000216288, ENST00000303622, ENST00000216288, ENSP00000408092, ENSP00000303698, ENST00000429436, ENSP00000450772, ENSP00000411397

Pharos - Targets

P27448

ZINC - Predictions - Purchasable

MARK3_HUMAN

HMDB Protein

HMDBP01179

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.944	17
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.916	13
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.786	9
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.72	5
UniProt:P11309 PIM1	1	PIM1 [nucleoplasm] (R-HSA-3215094)	0.527	2
UniProt:Q96L34 MARK4	1	MARK4 [cytosol] (R-HSA-5626653)	0.527	2
UniProt:P0DTD2 9b	3	p-S53-9b [cytosol] (R-COV-9758478) 9b [cytosol] (R-COV-9694649) 9b [mitochondrial outer membrane] (R-COV-9709803)	0.527	2
UniProt:P47756 CAPZB	1	CAPZB [cytosol] (R-HSA-879409)	0.527	2
UniProt:Q86UR5 RIMS1	1	RIMS1 [cytosol] (R-HSA-210407)	0.499	3
UniProt:P10636-8 MAPT	3	p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) MAPT-8 [cytosol] (R-HSA-9619519)	0.483	4

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