Reactome | PUM1 [cytosol]

PUM1 [cytosol]

Stable Identifier

R-HSA-434211

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Pumilio homolog 1, PUM1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14671 PUM1

Gene Names

PUM1, KIAA0099, PUMH1

Chain

initiator methionine:1, chain:2-1186

Reference Genes

BioGPS Gene:9698 PUM1

COSMIC (genes):PUM1 PUM1

CTD Gene:9698 PUM1

dbSNP Gene:9698 PUM1

ENSEMBL:ENSG00000134644 PUM1

HGNC:14957 PUM1

KEGG:hsa:9698 PUM1

Monarch:9698 PUM1

NCBI Gene:9698 PUM1

OMIM:607204 PUM1

UCSC:Q14671 PUM1

Reference Transcript

Other Identifiers

16684385

16684387

201166_PM_s_at

201166_s_at

2404258

2404259

2404264

2404268

2404276

2404280

2404286

2404304

2404312

2404313

2404315

40048_at

7914322

7914324

9698

A_23_P10815

A_23_P170820

A_24_P171345

D43951_at

GE57220

GO:0000932

GO:0003723

GO:0003730

GO:0005515

GO:0005654

GO:0005737

GO:0005829

GO:0006417

GO:0007283

GO:0008344

GO:0010494

GO:0010608

GO:0016441

GO:0022414

GO:0030154

GO:0030424

GO:0035196

GO:0035198

GO:0043226

GO:0043488

GO:0048863

GO:0051726

GO:0051983

GO:0060964

GO:0061157

GO:0061158

GO:1900246

GO:2000637

HMNXSV003028335

HMNXSV003041126

Hs.153834.0.S2_3p_a_at

ILMN_1783424

ILMN_2401155

PH_hs_0009253

PH_hs_0040230

RNA33594|snoRNA_scaRNA_190_91

TC01002446.hg

TC01002447.hg

g13491165_3p_a_at

Participates

as a component of

Golgi-associated vesicle interacting proteins [cytosol] (Homo sapiens)

as an input of

Recruitment Of Cytoplasmic Proteins To Vesicles (Homo sapiens)

Inferred To

pum1 [cytosol] (Danio rerio)

pum1 [cytosol] (Xenopus tropicalis)

Pum1 [cytosol] (Mus musculus)

Pum1 [cytosol] (Rattus norvegicus)

puf-9 [cytosol] (Caenorhabditis elegans)

puf-3 [cytosol] (Caenorhabditis elegans)

puf-5 [cytosol] (Caenorhabditis elegans)

pum [cytosol] (Drosophila melanogaster)

fbf-2 [cytosol] (Caenorhabditis elegans)

PUM1 [cytosol] (Bos taurus)

PUM1 [cytosol] (Canis familiaris)

PUM1 [cytosol] (Gallus gallus)

PUM1 [cytosol] (Sus scrofa)

fbf-1 [cytosol] (Caenorhabditis elegans)

puf-11 [cytosol] (Caenorhabditis elegans)

puf-6 [cytosol] (Caenorhabditis elegans)

puf-8 [cytosol] (Caenorhabditis elegans)

puf-7 [cytosol] (Caenorhabditis elegans)

Homologues of PUM1 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_055491.1, NP_001018494.1

OpenTargets

ENSG00000134644

ENSEMBL

ENSP00000401777, ENST00000257075, ENSP00000391723, ENST00000426105, ENST00000440538, ENSG00000134644, ENSP00000257075, ENSP00000362847, ENST00000373742

HPA

ENSG00000134644-PUM1

GeneCards

PUM1

PRO

Q14671

Pharos - Targets

Q14671

GlyGen

Q14671

PDB

3Q0P, 3BSB, 1M8Y, 1M8X, 1M8W, 1M8Z, 3Q0N, 3BSX, 3Q0O, 2YJY, 3Q0L, 3Q0M, 1IB2, 5YKI, 5YKH

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.745	6
UniProt:O15354 GPR37	1	GPR37 [plasma membrane] (R-HSA-5333623)	0.556	3
UniProt:P28799-2 GRN			0.556	3
UniProt:P28799 GRN	2	GRN [azurophil granule lumen] (R-HSA-6799168) GRN [extracellular region] (R-HSA-6806217)	0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P62258 YWHAE	1	YWHAE [cytosol] (R-HSA-194368)	0.539	5
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.528	5
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [secretory granule lumen] (R-HSA-6801530) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
UniProt:Q96A44 SPSB4	1	SPSB4 [cytosol] (R-HSA-976023)	0.527	3
UniProt:Q96PV0 SYNGAP1	1	SYNGAP1 [cytosol] (R-HSA-5658217)	0.527	2
UniProt:P06427 VE6			0.488	2
UniProt:Q84291 VE6			0.488	2
UniProt:P06929 VE6			0.488	2
UniProt:P31947 SFN	1	SFN [cytosol] (R-HSA-1445105)	0.471	4

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