p-Y705,S727-STAT3 [cytosol]

Stable Identifier
R-HSA-539048
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-S727,Y705-STAT3, p(Y705, S727)-STAT3, Signal transducer and activator of transcription 3, STAT3_HUMAN, STAT3
p-Y705,S727-STAT3 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
STAT3, APRF
Chain
initiator methionine:, chain:2-770
Other Identifiers
11720755_at
11720756_at
11750674_a_at
16845126
208991_PM_at
208991_at
208992_PM_s_at
208992_s_at
225289_PM_at
225289_at
289_at
3757837
3757839
3757841
3757842
3757844
3757845
3757846
3757848
3757854
3757856
3757858
3757860
3757861
3757862
3757864
3757865
3757867
3757868
3757870
3757871
3757873
3757874
3757875
3757881
3757883
3757885
3757888
3757889
3757905
3757906
39708_at
63330_at
6774
8015607
A_23_P100795
A_23_P107206
A_24_P116805
GE61038
GE61402
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001228
GO:0001659
GO:0001754
GO:0002376
GO:0003677
GO:0003700
GO:0003723
GO:0004879
GO:0005102
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0005975
GO:0006091
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0006606
GO:0006886
GO:0006913
GO:0006914
GO:0006952
GO:0006954
GO:0007165
GO:0007166
GO:0007179
GO:0007259
GO:0007399
GO:0008283
GO:0008285
GO:0010467
GO:0010507
GO:0010575
GO:0010628
GO:0010629
GO:0016071
GO:0016310
GO:0019221
GO:0019901
GO:0019903
GO:0019953
GO:0023052
GO:0030154
GO:0030335
GO:0030522
GO:0031047
GO:0031490
GO:0032355
GO:0032731
GO:0032733
GO:0032755
GO:0032757
GO:0032760
GO:0032870
GO:0032991
GO:0033210
GO:0035019
GO:0035591
GO:0035723
GO:0038110
GO:0038113
GO:0038154
GO:0040014
GO:0042127
GO:0042593
GO:0042755
GO:0042789
GO:0042802
GO:0042803
GO:0043226
GO:0043434
GO:0043491
GO:0043565
GO:0044320
GO:0044321
GO:0045648
GO:0045747
GO:0045766
GO:0045820
GO:0045893
GO:0045944
GO:0046983
GO:0048708
GO:0048856
GO:0048870
GO:0050728
GO:0051092
GO:0051726
GO:0055086
GO:0060019
GO:0060089
GO:0060090
GO:0060221
GO:0060259
GO:0060396
GO:0060397
GO:0061629
GO:0070102
GO:0070878
GO:0071310
GO:0072538
GO:0072540
GO:0090575
GO:0097009
GO:0097398
GO:0097696
GO:0106015
GO:0140110
GO:0140297
GO:0140313
GO:0140610
GO:1900017
GO:1901135
GO:1902895
GO:1904685
GO:1905564
GO:2000635
GO:2000737
GO:2001223
HMNXSV003017485
Hs.288544.0.S1_3p_at
ILMN_1663618
ILMN_2401978
ILMN_2410986
L29277_at
PH_hs_0019532
PH_hs_0025138
TC17001531.hg
TC17002638.hg
g12653684_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 727
Coordinate
727
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O4'-phospho-L-tyrosine at 705
Coordinate
705
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Interactors (88)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  20 0.919 15
 UniProt:P42224 STAT1  8 0.908 10
 UniProt:P43405 SYK  6 0.873 10
 UniProt:P40763 STAT3  12 0.842 8
 UniProt:P51813 BMX  3 0.83 8
 UniProt:P51451 BLK  2 0.83 9
 UniProt:P04626 ERBB2  20 0.775 9
 IntAct:EBI-1550784 CDKN1A      0.725 6
 UniProt:P08047 SP1  1 0.649 4
 UniProt:Q8TAE8 GADD45GIP1  1 0.635 4
 UniProt:P30626 SRI  1 0.635 3
 UniProt:Q16236 NFE2L2  13 0.625 5
 UniProt:P06401 PGR  3 0.623 3
 UniProt:P18031 PTPN1  2 0.623 2
 UniProt:P45984-1 MAPK9      0.602 3
 UniProt:Q810M5 ZDH19      0.576 4
 UniProt:P23458 JAK1  6 0.564 2
 UniProt:O43318 MAP3K7  10 0.558 4
 UniProt:P25791 LMO2  1 0.556 3
 UniProt:Q9DUM3 Q9DUM3      0.556 4
 UniProt:Q96HA1-2 POM121      0.556 3
 IntAct:EBI-10178797 4005      0.556 3
 UniProt:P12268 IMPDH2  4 0.556 3
 UniProt:Q9UER7 DAXX  13 0.556 4
 UniProt:Q9BXM7 PINK1  5 0.547 2
 UniProt:Q8N6P7 IL22RA1  2 0.547 2
 IntAct:EBI-9914958 STAT3      0.527 3
 IntAct:EBI-1265559 MYC      0.527 3
 UniProt:Q14289 PTK2B  3 0.527 4
 UniProt:P12931 SRC  6 0.527 5
 UniProt:O75116 ROCK2  2 0.524 3
 UniProt:Q14938-4 NFIX      0.524 3
 UniProt:Q14938-3 NFIX      0.524 3
 UniProt:Q9Y5S9 RBM8A  2 0.512 3
 UniProt:Q98PK8 Q98PK8      0.512 3
 UniProt:Q9BVP2 GNL3  1 0.508 2
 UniProt:Q9ULD0 OGDHL      0.508 2
 UniProt:Q13011 ECH1  3 0.508 2
 UniProt:P07384 CAPN1  4 0.508 2
 UniProt:P30084 ECHS1  17 0.508 3
 UniProt:Q92665 MRPS31  1 0.508 2
 UniProt:Q96G01 BICD1  1 0.508 2
 UniProt:Q8TE76 MORC4      0.508 2
 UniProt:O14874 BCKDK  5 0.508 2
 UniProt:P46781 RPS9  2 0.508 2
 UniProt:Q06520 SULT2A1  1 0.508 2
 UniProt:P22736 NR4A1  2 0.508 3
 UniProt:P31146 CORO1A  1 0.508 2
 IntAct:EBI-9825772 C-FOS PROMOTER REGION      0.499 2
 IntAct:EBI-10039972 MMP2      0.499 2
 UniProt:Q9NWQ8 PAG1  2 0.499 7
 UniProt:P32119 PRDX2  2 0.499 4
 IntAct:EBI-1108795 NPM      0.499 2
 IntAct:EBI-9980755 MIR-155      0.499 2
 IntAct:EBI-10952519 STAT      0.499 4
 UniProt:Q15910 EZH2  1 0.499 5
 UniProt:Q5VWN6 TASO2      0.488 2
 IntAct:EBI-10696506 MPZL1      0.488 2
 UniProt:Q92569 PIK3R3  2 0.488 2
 UniProt:Q8NEC7 GSTCD      0.488 2
 UniProt:P60409 KRTAP10-7  1 0.488 2
 UniProt:P35219 CAH8      0.488 2
 UniProt:Q9Y4J8-9 DTNA      0.488 2
 UniProt:P27986-2 PIK3R1      0.488 2
 UniProt:Q9NVE4 CCD87      0.488 2
 UniProt:Q96DZ7 T4S19      0.488 2
 UniProt:Q8IZQ1 WDFY3      0.488 2
 UniProt:Q6P1L5 F117B      0.488 2
 UniProt:Q86WK9 PAQR7      0.488 2
 UniProt:Q14847 LASP1      0.488 2
 UniProt:Q03181-2 PPARD      0.488 2
 UniProt:Q3KNS6 ZN829      0.488 2
 UniProt:Q7L591-3 DOK3      0.488 2
 UniProt:Q9UBX0 HESX1      0.488 2
 UniProt:Q6ZVU3 Q6ZVU3      0.488 2
 UniProt:Q9Y2X9 ZN281      0.488 2
 UniProt:Q9NP31 SH2D2A  1 0.488 2
 UniProt:P49137 MAPKAPK2  5 0.488 2
 UniProt:Q9Y3P9 RABGAP1  1 0.488 2
 UniProt:P22681 CBL  20 0.488 2
 UniProt:Q15672 TWIST1  1 0.488 2
 UniProt:P07949 RET  2 0.483 3
 UniProt:O95661 DIRA3      0.463 3
 UniProt:Q04206 RELA  7 0.463 4
 UniProt:P35232 PHB  2 0.463 2
 UniProt:P62993 GRB2  1 0.462 3
 UniProt:Q9UBE8 NLK  3 0.462 2
 UniProt:Q99062 CSF3R  5 0.462 4
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