Reactome | AdoHcy [nucleoplasm]

AdoHcy [nucleoplasm]

Stable Identifier

R-ALL-77502

Type

Chemical Compound [SimpleEntity]

Compartment

nucleoplasm

Synonyms

S-adenosylhomocysteine, S-adenosyl-L-homocysteine, SAH

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External Reference Information

External Reference

S-adenosyl-L-homocysteine zwitterion [ChEBI:57856]

Participates

as an input of

Prdm9 Trimethylates Histone H3 (murine, bovine) (Bos taurus)

as an output of

Box C/D snoRNP methylates ribonucleotides in pre-rRNA (Saccharomyces cerevisiae)
Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 (Saccharomyces cerevisiae)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 (Saccharomyces cerevisiae)
NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 (Homo sapiens)
DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 (Homo sapiens)
WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 (Homo sapiens)
NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)
TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) (Homo sapiens)
TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) (Homo sapiens)
TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Saccharomyces cerevisiae)
TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Homo sapiens)
TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 (Saccharomyces cerevisiae)
METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 (Homo sapiens)
NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 (Saccharomyces cerevisiae)
NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) (Homo sapiens)
TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) (Homo sapiens)
TRM10 methylates guanosine-9 in tRNA (Saccharomyces cerevisiae)
TRMT10A methylates guanosine-9 in tRNA (Homo sapiens)
NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 (Saccharomyces cerevisiae)
NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) (Homo sapiens)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Drosophila melanogaster)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Gallus gallus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Xenopus tropicalis)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Danio rerio)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Sus scrofa)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Bos taurus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Canis familiaris)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Rattus norvegicus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Mus musculus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Homo sapiens)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Saccharomyces cerevisiae)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Schizosaccharomyces pombe)