WHSC1 (MMSET, KMT3G) is able to mono-, di- and trimethylate lysine-28 (Kim et al. 2008). WHSC1L1 (KMT3F, WHISTLE) can di- and tri-methylate lysine-28 of histone H3 (H3K27) if it has been previously methylated at this residue (Kim et al. 2006).
Kee, HJ, Baek, HJ, Choe, NW, Kim, SM, Kim, JY, Kook, H, Kook, H, Eom, GH, Seo, SB
Kee, HJ, Kim, SK, Kim, SM, Choe, NW, Kook, H, Kim, YS, Eom, GH, Kook, H, Kim, JY, Seo, SB
histone H3 methyltransferase activity of WHSC1, WHSC1L1 [nucleoplasm]
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