NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46

Stable Identifier
R-SCE-6790149
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46
NCL1 (TRM4) transfers a methyl group from S-adenosylmethionine to the 5 position of cytidine-49 of tRNA(Asp) (Motorin and Grosjean 1999).
Literature References
Participants
Input
Output
Event Information
Go Biological Process
tRNA modification (0006400)
Catalyst Activity

tRNA (cytosine-5-)-methyltransferase activity of NCL1 [nucleoplasm]

Physical Entity
NCL1 [nucleoplasm] (Saccharomyces cerevisiae)
Activity
tRNA (cytosine-5-)-methyltransferase activity (GO:0016428)
Orthologous Events
NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) (Homo sapiens)
Authored
May, B  (2015-08-08)
Reviewed
Motorin, Y  (2015-08-25)
Jarrous, N  (2015-10-24)
Created
May, B  (2015-08-09)
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