PRMT6 is the predominant in vivo methylator of H3R2 (Hyllus et al. 2007, Guccione et al. 2007) and in addition able to methylate arginine-4 of histone H4 (R3H4) and arginine-4 of histone H2A (R3H2A) (Hyllus et al. 2007).
Schnabel, K, Schiltz, E, Bauer, UM, Stein, C, Hsieh, J, Imhof, A, Dou, Y, Hyllus, D
protein-arginine N-methyltransferase activity of PRMT6 [nucleoplasm]
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