PRMT6 methylates arginine-4 of histone H2A (H2AR3)

Stable Identifier
R-HSA-5205820
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
PRMT6 methylates arginine-4 of histone H2A
Locations in the PathwayBrowser
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PRMT6 is the predominant in vivo methylator of H3R2 (Hyllus et al. 2007, Guccione et al. 2007) and in addition able to methylate arginine-4 of histone H4 (R3H4) and arginine-4 of histone H2A (R3H2A) (Hyllus et al. 2007).

Literature References
PubMed ID Title Journal Year
18079182 PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation

Hyllus, D, Stein, C, Schnabel, K, Schiltz, E, Imhof, A, Dou, Y, Hsieh, J, Bauer, UM

Genes Dev. 2007
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein-arginine N-methyltransferase activity of PRMT6 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created