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AdoMet [nucleoplasm]
Stable Identifier
R-ALL-77087
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
S-adenosylmethionine, S-adenosyl-L-methionine, SAM
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prophase (Bos taurus)
Condensation of Prophase Chromosomes (Bos taurus)
SETD8 monomethylates histone H4 (Bos taurus)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
Cyclin A/B1/B2 associated events during G2/M transition (Bos taurus)
PP2A methylation by LCMT1 (Bos taurus)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Bos taurus)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
EHMT1:EHMT2 methylates IL6 promoter (Bos taurus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Bos taurus)
AdoMet [nucleoplasm]
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
PKMTs methylate histone lysines (Bos taurus)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Bos taurus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Bos taurus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Bos taurus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Bos taurus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Bos taurus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Bos taurus)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Bos taurus)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Bos taurus)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Bos taurus)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Bos taurus)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Bos taurus)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Bos taurus)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Bos taurus)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Bos taurus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Bos taurus)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Bos taurus)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Bos taurus)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Bos taurus)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Bos taurus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Bos taurus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Bos taurus)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Bos taurus)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Bos taurus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Bos taurus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Bos taurus)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Bos taurus)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Bos taurus)
AdoMet [nucleoplasm]
DNA Repair (Bos taurus)
DNA Double-Strand Break Repair (Bos taurus)
DNA Double Strand Break Response (Bos taurus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Bos taurus)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Bos taurus)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Bos taurus)
Epigenetic regulation of gene expression (Bos taurus)
Negative epigenetic regulation of rRNA expression (Bos taurus)
SIRT1 negatively regulates rRNA expression (Bos taurus)
eNoSC dimethylates histone H3 at lysine-9 (Bos taurus)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Bos taurus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Bos taurus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Bos taurus)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Bos taurus)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Bos taurus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Bos taurus)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Bos taurus)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Bos taurus)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
Regulation of TP53 Activity (Bos taurus)
Regulation of TP53 Activity through Methylation (Bos taurus)
EHMT1:EHMT2 dimethylates TP53 (Bos taurus)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Bos taurus)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Bos taurus)
AdoMet [nucleoplasm]
SETD9 methylates TP53 (Bos taurus)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Bos taurus)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Bos taurus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
AdoMet [nucleoplasm]
Metabolism of RNA (Bos taurus)
mRNA Capping (Bos taurus)
Methylation of GMP-cap by RNA Methyltransferase (Bos taurus)
AdoMet [nucleoplasm]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein methylation (Bos taurus)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Bos taurus)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Bos taurus)
AdoMet [nucleoplasm]
Signal Transduction (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Formation of the beta-catenin:TCF transactivating complex (Bos taurus)
SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)
AdoMet [nucleoplasm]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Prophase (Caenorhabditis elegans)
Condensation of Prophase Chromosomes (Caenorhabditis elegans)
SETD8 monomethylates histone H4 (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Caenorhabditis elegans)
G2/M Transition (Caenorhabditis elegans)
Cyclin A/B1/B2 associated events during G2/M transition (Caenorhabditis elegans)
PP2A methylation by LCMT1 (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular Senescence (Caenorhabditis elegans)
Oxidative Stress Induced Senescence (Caenorhabditis elegans)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Chromatin organization (Caenorhabditis elegans)
Chromatin modifying enzymes (Caenorhabditis elegans)
PKMTs methylate histone lysines (Caenorhabditis elegans)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Caenorhabditis elegans)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional regulation by RUNX1 (Caenorhabditis elegans)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Caenorhabditis elegans)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Metabolism of RNA (Caenorhabditis elegans)
mRNA Capping (Caenorhabditis elegans)
Methylation of GMP-cap by RNA Methyltransferase (Caenorhabditis elegans)
AdoMet [nucleoplasm]
Cell Cycle (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
Cyclin A/B1/B2 associated events during G2/M transition (Canis familiaris)
PP2A methylation by LCMT1 (Canis familiaris)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
Oxidative Stress Induced Senescence (Canis familiaris)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Canis familiaris)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Canis familiaris)
EHMT1:EHMT2 methylates IL6 promoter (Canis familiaris)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Canis familiaris)
AdoMet [nucleoplasm]
Chromatin organization (Canis familiaris)
Chromatin modifying enzymes (Canis familiaris)
PKMTs methylate histone lysines (Canis familiaris)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Canis familiaris)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Canis familiaris)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Canis familiaris)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Canis familiaris)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Canis familiaris)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Canis familiaris)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Canis familiaris)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Canis familiaris)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Canis familiaris)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Canis familiaris)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Canis familiaris)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Canis familiaris)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Canis familiaris)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Canis familiaris)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Canis familiaris)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Canis familiaris)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Canis familiaris)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Canis familiaris)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Canis familiaris)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Canis familiaris)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Canis familiaris)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Canis familiaris)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Canis familiaris)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Canis familiaris)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Canis familiaris)
AdoMet [nucleoplasm]
DNA Repair (Canis familiaris)
DNA Double-Strand Break Repair (Canis familiaris)
DNA Double Strand Break Response (Canis familiaris)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Canis familiaris)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Canis familiaris)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Canis familiaris)
Epigenetic regulation of gene expression (Canis familiaris)
Negative epigenetic regulation of rRNA expression (Canis familiaris)
SIRT1 negatively regulates rRNA expression (Canis familiaris)
eNoSC dimethylates histone H3 at lysine-9 (Canis familiaris)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Canis familiaris)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Canis familiaris)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Canis familiaris)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Canis familiaris)
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Canis familiaris)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Canis familiaris)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Canis familiaris)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
Regulation of TP53 Activity (Canis familiaris)
Regulation of TP53 Activity through Methylation (Canis familiaris)
EHMT1:EHMT2 dimethylates TP53 (Canis familiaris)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Canis familiaris)
AdoMet [nucleoplasm]
SETD9 methylates TP53 (Canis familiaris)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Canis familiaris)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Canis familiaris)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Canis familiaris)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Canis familiaris)
AdoMet [nucleoplasm]
Metabolism of RNA (Canis familiaris)
mRNA Capping (Canis familiaris)
Methylation of GMP-cap by RNA Methyltransferase (Canis familiaris)
AdoMet [nucleoplasm]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Protein methylation (Canis familiaris)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Canis familiaris)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Canis familiaris)
AdoMet [nucleoplasm]
Cell Cycle (Danio rerio)
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Prophase (Danio rerio)
Condensation of Prophase Chromosomes (Danio rerio)
SETD8 monomethylates histone H4 (Danio rerio)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Danio rerio)
G2/M Transition (Danio rerio)
Cyclin A/B1/B2 associated events during G2/M transition (Danio rerio)
PP2A methylation by LCMT1 (Danio rerio)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular Senescence (Danio rerio)
Oxidative Stress Induced Senescence (Danio rerio)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Danio rerio)
AdoMet [nucleoplasm]
Chromatin organization (Danio rerio)
Chromatin modifying enzymes (Danio rerio)
PKMTs methylate histone lysines (Danio rerio)
SETD6 methylates RELA in the NFkB complex (Danio rerio)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Danio rerio)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Danio rerio)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Danio rerio)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Danio rerio)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Danio rerio)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Danio rerio)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Danio rerio)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Danio rerio)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Danio rerio)
Epigenetic regulation of gene expression (Danio rerio)
PRC2 methylates histones and DNA (Danio rerio)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Danio rerio)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Danio rerio)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Danio rerio)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Danio rerio)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Danio rerio)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Danio rerio)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Danio rerio)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Danio rerio)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
Regulation of TP53 Activity (Danio rerio)
Regulation of TP53 Activity through Methylation (Danio rerio)
PRMT5 methylates TP53 (Danio rerio)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Danio rerio)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Danio rerio)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Danio rerio)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Danio rerio)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Danio rerio)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Danio rerio)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Danio rerio)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Danio rerio)
AdoMet [nucleoplasm]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Protein methylation (Danio rerio)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Danio rerio)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Danio rerio)
AdoMet [nucleoplasm]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
Mitotic G2-G2/M phases (Dictyostelium discoideum)
G2/M Transition (Dictyostelium discoideum)
Cyclin A/B1/B2 associated events during G2/M transition (Dictyostelium discoideum)
PP2A methylation by LCMT1 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
Chromatin organization (Dictyostelium discoideum)
Chromatin modifying enzymes (Dictyostelium discoideum)
PKMTs methylate histone lysines (Dictyostelium discoideum)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Dictyostelium discoideum)
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Dictyostelium discoideum)
AdoMet [nucleoplasm]
DNA Repair (Dictyostelium discoideum)
DNA Double-Strand Break Repair (Dictyostelium discoideum)
DNA Double Strand Break Response (Dictyostelium discoideum)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Dictyostelium discoideum)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Dictyostelium discoideum)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Dictyostelium discoideum)
Epigenetic regulation of gene expression (Dictyostelium discoideum)
Negative epigenetic regulation of rRNA expression (Dictyostelium discoideum)
SIRT1 negatively regulates rRNA expression (Dictyostelium discoideum)
eNoSC dimethylates histone H3 at lysine-9 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
Metabolism of RNA (Dictyostelium discoideum)
mRNA Capping (Dictyostelium discoideum)
Methylation of GMP-cap by RNA Methyltransferase (Dictyostelium discoideum)
AdoMet [nucleoplasm]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Protein methylation (Dictyostelium discoideum)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Dictyostelium discoideum)
AdoMet [nucleoplasm]
Cell Cycle (Drosophila melanogaster)
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Prophase (Drosophila melanogaster)
Condensation of Prophase Chromosomes (Drosophila melanogaster)
SETD8 monomethylates histone H4 (Drosophila melanogaster)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Drosophila melanogaster)
G2/M Transition (Drosophila melanogaster)
Cyclin A/B1/B2 associated events during G2/M transition (Drosophila melanogaster)
PP2A methylation by LCMT1 (Drosophila melanogaster)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Oxidative Stress Induced Senescence (Drosophila melanogaster)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Drosophila melanogaster)
EHMT1:EHMT2 methylates IL6 promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Chromatin organization (Drosophila melanogaster)
Chromatin modifying enzymes (Drosophila melanogaster)
PKMTs methylate histone lysines (Drosophila melanogaster)
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Drosophila melanogaster)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Drosophila melanogaster)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Drosophila melanogaster)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Drosophila melanogaster)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Drosophila melanogaster)
AdoMet [nucleoplasm]
DNA Repair (Drosophila melanogaster)
DNA Double-Strand Break Repair (Drosophila melanogaster)
DNA Double Strand Break Response (Drosophila melanogaster)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Drosophila melanogaster)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Drosophila melanogaster)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Drosophila melanogaster)
Epigenetic regulation of gene expression (Drosophila melanogaster)
Negative epigenetic regulation of rRNA expression (Drosophila melanogaster)
SIRT1 negatively regulates rRNA expression (Drosophila melanogaster)
eNoSC dimethylates histone H3 at lysine-9 (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Drosophila melanogaster)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Drosophila melanogaster)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Drosophila melanogaster)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Drosophila melanogaster)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Drosophila melanogaster)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
Regulation of TP53 Activity (Drosophila melanogaster)
Regulation of TP53 Activity through Methylation (Drosophila melanogaster)
EHMT1:EHMT2 dimethylates TP53 (Drosophila melanogaster)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Drosophila melanogaster)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Drosophila melanogaster)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Drosophila melanogaster)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Drosophila melanogaster)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Drosophila melanogaster)
AdoMet [nucleoplasm]
Metabolism of RNA (Drosophila melanogaster)
mRNA Capping (Drosophila melanogaster)
Methylation of GMP-cap by RNA Methyltransferase (Drosophila melanogaster)
AdoMet [nucleoplasm]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein methylation (Drosophila melanogaster)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Drosophila melanogaster)
AdoMet [nucleoplasm]
Signal Transduction (Drosophila melanogaster)
Signaling by WNT (Drosophila melanogaster)
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Formation of the beta-catenin:TCF transactivating complex (Drosophila melanogaster)
SET1 complex trimethylates H3K4 at the MYC gene (Drosophila melanogaster)
AdoMet [nucleoplasm]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Prophase (Gallus gallus)
Condensation of Prophase Chromosomes (Gallus gallus)
SETD8 monomethylates histone H4 (Gallus gallus)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular Senescence (Gallus gallus)
Oxidative Stress Induced Senescence (Gallus gallus)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Gallus gallus)
AdoMet [nucleoplasm]
Chromatin organization (Gallus gallus)
Chromatin modifying enzymes (Gallus gallus)
PKMTs methylate histone lysines (Gallus gallus)
SETD6 methylates RELA in the NFkB complex (Gallus gallus)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Gallus gallus)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Gallus gallus)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Gallus gallus)
AdoMet [nucleoplasm]
DNA Repair (Gallus gallus)
DNA Double-Strand Break Repair (Gallus gallus)
DNA Double Strand Break Response (Gallus gallus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Gallus gallus)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Gallus gallus)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Gallus gallus)
Epigenetic regulation of gene expression (Gallus gallus)
PRC2 methylates histones and DNA (Gallus gallus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Gallus gallus)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Gallus gallus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Gallus gallus)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Gallus gallus)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Gallus gallus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Gallus gallus)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Gallus gallus)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Gallus gallus)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional regulation by RUNX1 (Gallus gallus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Gallus gallus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Gallus gallus)
AdoMet [nucleoplasm]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Protein methylation (Gallus gallus)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Gallus gallus)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Gallus gallus)
AdoMet [nucleoplasm]
Signal Transduction (Gallus gallus)
Signaling by WNT (Gallus gallus)
TCF dependent signaling in response to WNT (Gallus gallus)
Formation of the beta-catenin:TCF transactivating complex (Gallus gallus)
SET1 complex trimethylates H3K4 at the MYC gene (Gallus gallus)
AdoMet [nucleoplasm]
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Condensation of Prophase Chromosomes (Homo sapiens)
SETD8 monomethylates histone H4 (Homo sapiens)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
PP2A methylation by LCMT1 (Homo sapiens)
AdoMet [nucleoplasm]
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Homo sapiens)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Homo sapiens)
EHMT1:EHMT2 methylates IL6 promoter (Homo sapiens)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Homo sapiens)
AdoMet [nucleoplasm]
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
PKMTs methylate histone lysines (Homo sapiens)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Homo sapiens)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Homo sapiens)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Homo sapiens)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Homo sapiens)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Homo sapiens)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Homo sapiens)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Homo sapiens)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Homo sapiens)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Homo sapiens)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Homo sapiens)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Homo sapiens)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Homo sapiens)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Homo sapiens)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Homo sapiens)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Homo sapiens)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Homo sapiens)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Homo sapiens)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Homo sapiens)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Homo sapiens)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Homo sapiens)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Homo sapiens)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Homo sapiens)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Homo sapiens)
AdoMet [nucleoplasm]
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
DNA Double Strand Break Response (Homo sapiens)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Homo sapiens)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Homo sapiens)
AdoMet [nucleoplasm]
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Replacement of protamines by nucleosomes in the male pronucleus (Homo sapiens)
METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) (Homo sapiens)
AdoMet [nucleoplasm]
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective pyroptosis (Homo sapiens)
The GSDME gene promoter is hypermethylated (Homo sapiens)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
DNA methylation (Homo sapiens)
DNMT1 methylates cytosine in hemimethylated DNA (Homo sapiens)
AdoMet [nucleoplasm]
DNMT3A:DNMT3L methylates cytosine in DNA (Homo sapiens)
AdoMet [nucleoplasm]
DNMT3B:DNMT3L methylates cytosine in DNA (Homo sapiens)
AdoMet [nucleoplasm]
Epigenetic regulation by WDR5-containing histone modifying complexes (Homo sapiens)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Homo sapiens)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Homo sapiens)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Homo sapiens)
KMT2D,(KMT2C) complex monomethylates nucleosomes at PPARG:RXRA-bound enhancers (Homo sapiens)
AdoMet [nucleoplasm]
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
NoRC:HDAC:DNMT deacetylates histone H4 and methylates histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
NoRC:HDAC:DNMT methylates cytosine of the rRNA genes (Homo sapiens)
AdoMet [nucleoplasm]
SIRT1 negatively regulates rRNA expression (Homo sapiens)
eNoSC dimethylates histone H3 at lysine-9 (Homo sapiens)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Homo sapiens)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Homo sapiens)
AdoMet [nucleoplasm]
Positive epigenetic regulation of rRNA expression (Homo sapiens)
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression (Homo sapiens)
TTF1:rRNA promoter:ERCC6:EHMT2 complex dimethylates histone H3 at lysine-9 (Homo sapiens)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Homo sapiens)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Homo sapiens)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Homo sapiens)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) (Homo sapiens)
DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA (Homo sapiens)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Homo sapiens)
EHMT1,EHMT2 trimethylates lysine-16 of ATF7IP (Homo sapiens)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Homo sapiens)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Homo sapiens)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Activity through Methylation (Homo sapiens)
EHMT1:EHMT2 dimethylates TP53 (Homo sapiens)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Homo sapiens)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Homo sapiens)
AdoMet [nucleoplasm]
SETD9 methylates TP53 (Homo sapiens)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Homo sapiens)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Homo sapiens)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Homo sapiens)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Homo sapiens)
AdoMet [nucleoplasm]
RUNX1 regulates transcription of genes involved in differentiation of HSCs (Homo sapiens)
KMT2A trimethylates nucleosomes at the SPI1 gene locus producing H3K4Me3 mark (Homo sapiens)
AdoMet [nucleoplasm]
Metabolism of RNA (Homo sapiens)
mRNA Capping (Homo sapiens)
Methylation of GMP-cap by RNA Methyltransferase (Homo sapiens)
AdoMet [nucleoplasm]
rRNA processing (Homo sapiens)
rRNA processing in the nucleus and cytosol (Homo sapiens)
rRNA modification in the nucleus and cytosol (Homo sapiens)
Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides (Homo sapiens)
AdoMet [nucleoplasm]
DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 (Homo sapiens)
AdoMet [nucleoplasm]
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
AdoMet [nucleoplasm]
NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 (Homo sapiens)
AdoMet [nucleoplasm]
WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 (Homo sapiens)
AdoMet [nucleoplasm]
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 (Homo sapiens)
AdoMet [nucleoplasm]
NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) (Homo sapiens)
AdoMet [nucleoplasm]
NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)
AdoMet [nucleoplasm]
NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) (Homo sapiens)
AdoMet [nucleoplasm]
Synthesis of wybutosine at G37 of tRNA(Phe) (Homo sapiens)
TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Homo sapiens)
AdoMet [nucleoplasm]
TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) (Homo sapiens)
AdoMet [nucleoplasm]
TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) (Homo sapiens)
AdoMet [nucleoplasm]
TRMT10A methylates guanosine-9 in tRNA (Homo sapiens)
AdoMet [nucleoplasm]
TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) (Homo sapiens)
AdoMet [nucleoplasm]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein methylation (Homo sapiens)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Homo sapiens)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Homo sapiens)
AdoMet [nucleoplasm]
Reproduction (Homo sapiens)
Meiosis (Homo sapiens)
Meiotic recombination (Homo sapiens)
PRDM9 trimethylates histone H3 (Homo sapiens)
AdoMet [nucleoplasm]
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)
SET1 complex trimethylates H3K4 at the MYC gene (Homo sapiens)
AdoMet [nucleoplasm]
Cell Cycle (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
Cyclin A/B1/B2 associated events during G2/M transition (Mus musculus)
PP2A methylation by LCMT1 (Mus musculus)
AdoMet [nucleoplasm]
Chromatin organization (Mus musculus)
Chromatin modifying enzymes (Mus musculus)
PKMTs methylate histone lysines (Mus musculus)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Mus musculus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Mus musculus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Mus musculus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Mus musculus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Mus musculus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Mus musculus)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Mus musculus)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Mus musculus)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Mus musculus)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Mus musculus)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Mus musculus)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Mus musculus)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Mus musculus)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Mus musculus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Mus musculus)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Mus musculus)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Mus musculus)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Mus musculus)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Mus musculus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Mus musculus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Mus musculus)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Mus musculus)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Mus musculus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Mus musculus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Mus musculus)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Mus musculus)
AdoMet [nucleoplasm]
DNA Repair (Mus musculus)
DNA Double-Strand Break Repair (Mus musculus)
DNA Double Strand Break Response (Mus musculus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Mus musculus)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Mus musculus)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Mus musculus)
Epigenetic regulation of gene expression (Mus musculus)
PRC2 methylates histones and DNA (Mus musculus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Mus musculus)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Mus musculus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Mus musculus)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Mus musculus)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Mus musculus)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Activity through Methylation (Mus musculus)
EHMT1:EHMT2 dimethylates TP53 (Mus musculus)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Mus musculus)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Mus musculus)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Mus musculus)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Mus musculus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Mus musculus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Mus musculus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Mus musculus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Mus musculus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Mus musculus)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Mus musculus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Mus musculus)
AdoMet [nucleoplasm]
Metabolism of RNA (Mus musculus)
mRNA Capping (Mus musculus)
Methylation of GMP-cap by RNA Methyltransferase (Mus musculus)
AdoMet [nucleoplasm]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Protein methylation (Mus musculus)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Mus musculus)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Mus musculus)
AdoMet [nucleoplasm]
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
M Phase (Plasmodium falciparum)
Mitotic Prophase (Plasmodium falciparum)
Condensation of Prophase Chromosomes (Plasmodium falciparum)
SETD8 monomethylates histone H4 (Plasmodium falciparum)
AdoMet [nucleoplasm]
Chromatin organization (Plasmodium falciparum)
Chromatin modifying enzymes (Plasmodium falciparum)
PKMTs methylate histone lysines (Plasmodium falciparum)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Plasmodium falciparum)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Plasmodium falciparum)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Plasmodium falciparum)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Plasmodium falciparum)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Plasmodium falciparum)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Plasmodium falciparum)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Plasmodium falciparum)
AdoMet [nucleoplasm]
Cell Cycle (Rattus norvegicus)
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Prophase (Rattus norvegicus)
Condensation of Prophase Chromosomes (Rattus norvegicus)
SETD8 monomethylates histone H4 (Rattus norvegicus)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Rattus norvegicus)
G2/M Transition (Rattus norvegicus)
Cyclin A/B1/B2 associated events during G2/M transition (Rattus norvegicus)
PP2A methylation by LCMT1 (Rattus norvegicus)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
Oxidative Stress Induced Senescence (Rattus norvegicus)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Rattus norvegicus)
EHMT1:EHMT2 methylates IL6 promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Chromatin organization (Rattus norvegicus)
Chromatin modifying enzymes (Rattus norvegicus)
PKMTs methylate histone lysines (Rattus norvegicus)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Rattus norvegicus)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Rattus norvegicus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Rattus norvegicus)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Rattus norvegicus)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Rattus norvegicus)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Rattus norvegicus)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Rattus norvegicus)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Rattus norvegicus)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Rattus norvegicus)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Rattus norvegicus)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Rattus norvegicus)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Rattus norvegicus)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Rattus norvegicus)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Rattus norvegicus)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Rattus norvegicus)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Rattus norvegicus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Rattus norvegicus)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Rattus norvegicus)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Rattus norvegicus)
AdoMet [nucleoplasm]
DNA Repair (Rattus norvegicus)
DNA Double-Strand Break Repair (Rattus norvegicus)
DNA Double Strand Break Response (Rattus norvegicus)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Rattus norvegicus)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Rattus norvegicus)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Rattus norvegicus)
Epigenetic regulation of gene expression (Rattus norvegicus)
Negative epigenetic regulation of rRNA expression (Rattus norvegicus)
SIRT1 negatively regulates rRNA expression (Rattus norvegicus)
eNoSC dimethylates histone H3 at lysine-9 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Rattus norvegicus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Rattus norvegicus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Rattus norvegicus)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Rattus norvegicus)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Rattus norvegicus)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Rattus norvegicus)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Rattus norvegicus)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Rattus norvegicus)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
Regulation of TP53 Activity (Rattus norvegicus)
Regulation of TP53 Activity through Methylation (Rattus norvegicus)
EHMT1:EHMT2 dimethylates TP53 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Rattus norvegicus)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Rattus norvegicus)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Rattus norvegicus)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Rattus norvegicus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Rattus norvegicus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Rattus norvegicus)
AdoMet [nucleoplasm]
Metabolism of RNA (Rattus norvegicus)
mRNA Capping (Rattus norvegicus)
Methylation of GMP-cap by RNA Methyltransferase (Rattus norvegicus)
AdoMet [nucleoplasm]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Protein methylation (Rattus norvegicus)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Rattus norvegicus)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Rattus norvegicus)
AdoMet [nucleoplasm]
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
Mitotic G2-G2/M phases (Saccharomyces cerevisiae)
G2/M Transition (Saccharomyces cerevisiae)
Cyclin A/B1/B2 associated events during G2/M transition (Saccharomyces cerevisiae)
PP2A methylation by LCMT1 (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
Chromatin organization (Saccharomyces cerevisiae)
Chromatin modifying enzymes (Saccharomyces cerevisiae)
PKMTs methylate histone lysines (Saccharomyces cerevisiae)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Saccharomyces cerevisiae)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
DNA Repair (Saccharomyces cerevisiae)
DNA Double-Strand Break Repair (Saccharomyces cerevisiae)
DNA Double Strand Break Response (Saccharomyces cerevisiae)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Saccharomyces cerevisiae)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Saccharomyces cerevisiae)
Epigenetic regulation of gene expression (Saccharomyces cerevisiae)
Negative epigenetic regulation of rRNA expression (Saccharomyces cerevisiae)
SIRT1 negatively regulates rRNA expression (Saccharomyces cerevisiae)
eNoSC dimethylates histone H3 at lysine-9 (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
Metabolism of RNA (Saccharomyces cerevisiae)
mRNA Capping (Saccharomyces cerevisiae)
Methylation of GMP-cap by RNA Methyltransferase (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Protein methylation (Saccharomyces cerevisiae)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Saccharomyces cerevisiae)
AdoMet [nucleoplasm]
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
Mitotic G2-G2/M phases (Schizosaccharomyces pombe)
G2/M Transition (Schizosaccharomyces pombe)
Cyclin A/B1/B2 associated events during G2/M transition (Schizosaccharomyces pombe)
PP2A methylation by LCMT1 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
Chromatin organization (Schizosaccharomyces pombe)
Chromatin modifying enzymes (Schizosaccharomyces pombe)
PKMTs methylate histone lysines (Schizosaccharomyces pombe)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Schizosaccharomyces pombe)
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
DNA Repair (Schizosaccharomyces pombe)
DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
DNA Double Strand Break Response (Schizosaccharomyces pombe)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Schizosaccharomyces pombe)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Schizosaccharomyces pombe)
Epigenetic regulation of gene expression (Schizosaccharomyces pombe)
Negative epigenetic regulation of rRNA expression (Schizosaccharomyces pombe)
SIRT1 negatively regulates rRNA expression (Schizosaccharomyces pombe)
eNoSC dimethylates histone H3 at lysine-9 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
Metabolism of RNA (Schizosaccharomyces pombe)
mRNA Capping (Schizosaccharomyces pombe)
Methylation of GMP-cap by RNA Methyltransferase (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Protein methylation (Schizosaccharomyces pombe)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Schizosaccharomyces pombe)
AdoMet [nucleoplasm]
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Prophase (Sus scrofa)
Condensation of Prophase Chromosomes (Sus scrofa)
SETD8 monomethylates histone H4 (Sus scrofa)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Sus scrofa)
G2/M Transition (Sus scrofa)
Cyclin A/B1/B2 associated events during G2/M transition (Sus scrofa)
PP2A methylation by LCMT1 (Sus scrofa)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Sus scrofa)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Sus scrofa)
EHMT1:EHMT2 methylates IL6 promoter (Sus scrofa)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Sus scrofa)
AdoMet [nucleoplasm]
Chromatin organization (Sus scrofa)
Chromatin modifying enzymes (Sus scrofa)
PKMTs methylate histone lysines (Sus scrofa)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Sus scrofa)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates dimethyl-lysine-80 of histone H3 (H3K79) (Sus scrofa)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates lysine-80 of histone H3 (H3K79) (Sus scrofa)
AdoMet [nucleoplasm]
DOT1L (KMT4) methylates methyl-lysine-80 of histone H3 (H3K79) (Sus scrofa)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates lysine-10 of histone H3 (H3K9) (Sus scrofa)
AdoMet [nucleoplasm]
EHMT1:EHMT2 (KMT1D:KMT1C) methylates methyl-lysine-10 of histone H3 (H3K9) (Sus scrofa)
AdoMet [nucleoplasm]
PRC2 (EZH2) Core:AEBP2 methylates lysine-28 of histone H3 (H3K27) (Sus scrofa)
AdoMet [nucleoplasm]
SETD2 (KMT3A) methylates dimethyl-lysine-37 of histone H3 (H3K36) (Sus scrofa)
AdoMet [nucleoplasm]
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Sus scrofa)
AdoMet [nucleoplasm]
SETD6 methylates RELA in the NFkB complex (Sus scrofa)
AdoMet [nucleoplasm]
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Sus scrofa)
AdoMet [nucleoplasm]
SUV39H1 (KMT1A), SUV39H2 (KTM1B), SETDB1 (KMT1E), SETDB2 (KMT1F) methylate dimethyl-lysine-10 of histone H3 (H3K9) (Sus scrofa)
AdoMet [nucleoplasm]
SUV420H1 (KMT5B), SUV420H2 (KMT5C), (possibly SMYD3 (KMT3E)) methylate methyl-lysine-21 of histone H4 (H4K20) (Sus scrofa)
AdoMet [nucleoplasm]
SUV420H1, SUV420H2, (possibly SMYD3 (KMT3E)) methylate dimethyl-lysine-21 of histone H4 (H4K20) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Sus scrofa)
AdoMet [nucleoplasm]
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Sus scrofa)
AdoMet [nucleoplasm]
RMTs methylate histone arginines (Sus scrofa)
CARM1 methylates arginine-18 (H3R17) of histone H3 (Sus scrofa)
AdoMet [nucleoplasm]
CARM1 methylates arginine-27 of histone H3 (H3R26) (Sus scrofa)
AdoMet [nucleoplasm]
CARM1, PRMT6 methylate arginine-3 of histone H3 (H3R2) (Sus scrofa)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-9 of histone H3 (H3R8) (Sus scrofa)
AdoMet [nucleoplasm]
CCND1:CDK4:PRMT5:pT5-WDR77 methylates methyl-arginine-9 of histone H3 (Sus scrofa)
AdoMet [nucleoplasm]
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Sus scrofa)
AdoMet [nucleoplasm]
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Sus scrofa)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Sus scrofa)
AdoMet [nucleoplasm]
PRMT1,PRMT6 methylate methyl-lysine-4 of histone H4 (Sus scrofa)
AdoMet [nucleoplasm]
PRMT5:WDR77, PRMT7 methylate arginine-3 of histone H3 (H3R2) (Sus scrofa)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Sus scrofa)
AdoMet [nucleoplasm]
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
DNA Double Strand Break Response (Sus scrofa)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Sus scrofa)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Sus scrofa)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Sus scrofa)
Epigenetic regulation of gene expression (Sus scrofa)
Negative epigenetic regulation of rRNA expression (Sus scrofa)
SIRT1 negatively regulates rRNA expression (Sus scrofa)
eNoSC dimethylates histone H3 at lysine-9 (Sus scrofa)
AdoMet [nucleoplasm]
PRC2 methylates histones and DNA (Sus scrofa)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Sus scrofa)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Sus scrofa)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements (Sus scrofa)
Regulation of endogenous retroelements by KRAB-ZFP proteins (Sus scrofa)
SETDB1 in ATF7IP:SETDB1:SUMO2-6K-TRIM28:KRAB-ZFP:retroelement trimethylates lysine-9 of histone H3 in nucleosomes (Sus scrofa)
AdoMet [nucleoplasm]
Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex (Sus scrofa)
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1 RNA trimethylates lysine-9 of histone H3 (H3K9me3) (Sus scrofa)
AdoMet [nucleoplasm]
SETDB1 in me3-K16-ATF7IP:SETDB1:MORC2:HUSH complex:L1HS,L1PA2,3 heterochromatin trimethylates lysine-9 of histone H3 in adjacent nucleosome (Sus scrofa)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Activity through Methylation (Sus scrofa)
EHMT1:EHMT2 dimethylates TP53 (Sus scrofa)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Sus scrofa)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Sus scrofa)
AdoMet [nucleoplasm]
SETD9 methylates TP53 (Sus scrofa)
AdoMet [nucleoplasm]
SMYD2 methylates TP53 (Sus scrofa)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Sus scrofa)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
PRMT1 arginine-methylates RUNX1 (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)
AdoMet [nucleoplasm]
Metabolism of RNA (Sus scrofa)
mRNA Capping (Sus scrofa)
Methylation of GMP-cap by RNA Methyltransferase (Sus scrofa)
AdoMet [nucleoplasm]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Protein methylation (Sus scrofa)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Sus scrofa)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Sus scrofa)
AdoMet [nucleoplasm]
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Prophase (Xenopus tropicalis)
Condensation of Prophase Chromosomes (Xenopus tropicalis)
SETD8 monomethylates histone H4 (Xenopus tropicalis)
AdoMet [nucleoplasm]
Mitotic G2-G2/M phases (Xenopus tropicalis)
G2/M Transition (Xenopus tropicalis)
Cyclin A/B1/B2 associated events during G2/M transition (Xenopus tropicalis)
PP2A methylation by LCMT1 (Xenopus tropicalis)
AdoMet [nucleoplasm]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular Senescence (Xenopus tropicalis)
Oxidative Stress Induced Senescence (Xenopus tropicalis)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Senescence-Associated Secretory Phenotype (SASP) (Xenopus tropicalis)
EHMT1:EHMT2 methylates IL6 promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
EHMT1:EHMT2 methylates IL8 promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Chromatin organization (Xenopus tropicalis)
Chromatin modifying enzymes (Xenopus tropicalis)
RMTs methylate histone arginines (Xenopus tropicalis)
PRMT1 methylates arginine-12 of histone H2A (H2AR11) (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 methylates histone H2A arginine-30 (H2AR29) (Xenopus tropicalis)
AdoMet [nucleoplasm]
Gene expression (Transcription) (Xenopus tropicalis)
Epigenetic regulation of gene expression (Xenopus tropicalis)
PRC2 methylates histones and DNA (Xenopus tropicalis)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRC2 trimethylates histone H3 at lysine-27 (Xenopus tropicalis)
AdoMet [nucleoplasm]
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
Regulation of TP53 Activity (Xenopus tropicalis)
Regulation of TP53 Activity through Methylation (Xenopus tropicalis)
EHMT1:EHMT2 dimethylates TP53 (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT5 methylates TP53 (Xenopus tropicalis)
AdoMet [nucleoplasm]
SETD8 methylates TP53 (Xenopus tropicalis)
AdoMet [nucleoplasm]
Transcriptional regulation by RUNX1 (Xenopus tropicalis)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Xenopus tropicalis)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Xenopus tropicalis)
AdoMet [nucleoplasm]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Protein methylation (Xenopus tropicalis)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Xenopus tropicalis)
AdoMet [nucleoplasm]
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Xenopus tropicalis)
AdoMet [nucleoplasm]
External Reference Information
External Reference
S-adenosyl-L-methionine zwitterion [ChEBI:59789]
Participates
as an input of
Box C/D snoRNP methylates ribonucleotides in pre-rRNA (Saccharomyces cerevisiae)
Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides (Homo sapiens)
EMG1 of the SSU processome methylates pseudouridine-1191 of 18S rRNA yielding N(1)-methylpseudouridine-1191 (Saccharomyces cerevisiae)
EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 (Homo sapiens)
NOP2 methylates cytosine-2870 of 25S rRNA yielding 5-methylcytosine-2870 (Saccharomyces cerevisiae)
NOP2 (NSUN1) methylates cytidine-4447 of 28S rRNA yielding 5-methylcytidine-4447 (Homo sapiens)
DIMT1 dimethylates adenosine-1850,1851 of 18S rRNA yielding 6-dimethyladenosine-1850,1851 (Homo sapiens)
WBSCR22:TRMT112 methylates guanosine-1639 of 18S rRNA yielding 7-methylguanosine-1639 (Homo sapiens)
NSUN2 methylates cytidine-40, cytidine-48, cytidine-49, cytidine-50 of tRNA(GLY)(GCC) (Homo sapiens)
TRMT1 (hTRM1) dimethylates guanosine-26 of tRNA(Tyr) (Homo sapiens)
TRDMT1 (DNMT2) methylates cytidine-38 of tRNA(Asp) (Homo sapiens)
TRM5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Saccharomyces cerevisiae)
TRMT5 methylates guanosine yielding 1-methylguanosine at nucleotide 37 of tRNA(Phe) (Homo sapiens)
TRM8:TRM82 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 (Saccharomyces cerevisiae)
METTL1:WDR4 methylates guanosine-46 of tRNA(Phe) yielding 7-methylguanosine-46 (Homo sapiens)
NCL1 (TRM4) methylates cytidine-49 of tRNA(Asp) yielding 5-methylcytidine-46 (Saccharomyces cerevisiae)
NSUN2 methylates cytidine-48 and cytidine-49 of tRNA(Asp)(GUC) (Homo sapiens)
TRMT6:TRMT61A methylate adenosine yielding 1-methyladenosine at nucleotide 58 of tRNA(Met) (Homo sapiens)
TRM10 methylates guanosine-9 in tRNA (Saccharomyces cerevisiae)
TRMT10A methylates guanosine-9 in tRNA (Homo sapiens)
NCL1 (TRM4) methylates cytidine-34 of unspliced tRNA(Leu) yielding 5-methylcytidine-34 (Saccharomyces cerevisiae)
NSUN2 methylates cytidine-34, cytidine-48 of unspliced tRNA(Leu)(CAA) (Homo sapiens)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Drosophila melanogaster)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Gallus gallus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Xenopus tropicalis)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Danio rerio)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Sus scrofa)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Bos taurus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Canis familiaris)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Rattus norvegicus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Mus musculus)
METTL22 transfers 3xCH3 from 3xAdoMet to KIN (Homo sapiens)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Saccharomyces cerevisiae)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Schizosaccharomyces pombe)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Dictyostelium discoideum)
METTL21A transfers 3xCH3 from 3xAdoMet to HSPA8 (Gallus gallus)