Reactome | RBM8A [nucleoplasm]

RBM8A [nucleoplasm]

Stable Identifier

R-HSA-156659

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

RBM8A/Y14

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - RNA Polymerase II Transcription Termination (Homo sapiens)
    - Cleavage of mRNA at the 3'-end (Homo sapiens)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Homo sapiens)
        
        EJC [nucleoplasm] (Homo sapiens)
        
        Core EJC [nucleoplasm] (Homo sapiens)
        
        Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
        
        RBM8A [nucleoplasm] (Homo sapiens)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Homo sapiens)
        
        EJC [nucleoplasm] (Homo sapiens)
        
        Core EJC [nucleoplasm] (Homo sapiens)
        
        Magoh-Y14 complex [nucleoplasm] (Homo sapiens)
        
        RBM8A [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9Y5S9 RBM8A

Gene Names

RBM8A, RBM8, HSPC114, MDS014

Chain

initiator methionine:, chain:2-174

Reference Genes

COSMIC (genes):RBM8A RBM8A

dbSNP Gene:9939 RBM8A

ENSEMBL:ENSG00000265241 RBM8A

Participates

as a component of

Magoh-Y14 complex [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RBM8A [cytosol]

Inferred To

RBM8A [nucleoplasm] (Canis familiaris)

RBM8A [nucleoplasm] (Gallus gallus)

RBM8A [nucleoplasm] (Plasmodium falciparum)

RBM8A [nucleoplasm] (Schizosaccharomyces pombe)

RBM8A [nucleoplasm] (Sus scrofa)

rbm8a [nucleoplasm] (Danio rerio)

rbm8a [nucleoplasm] (Xenopus tropicalis)

rnp-4 [nucleoplasm] (Caenorhabditis elegans)

tsu [nucleoplasm] (Drosophila melanogaster)

rbm8A [nucleoplasm] (Dictyostelium discoideum)

Rbm8a [nucleoplasm] (Mus musculus)

Rbm8a [nucleoplasm] (Rattus norvegicus)

Ghost homologue of RBM8A [nucleoplasm] (Bos taurus)

Ghost homologue of RBM8A [nucleoplasm] (Saccharomyces cerevisiae)

Interactors (13)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.947	22
UniProt:Q9BZI7 UPF3B	2	UPF3B [cytosol] (R-HSA-159258) UPF3B [nucleoplasm] (R-HSA-156776)	0.914	10
UniProt:O15234 CASC3	2	CASC3 [nucleoplasm] (R-HSA-8849148) CASC3 [cytosol] (R-HSA-927807)	0.857	6
UniProt:Q92900 UPF1	2	p-4S-UPF1 [cytosol] (R-HSA-927856) UPF1 [cytosol] (R-HSA-927734)	0.725	5
UniProt:P52298 NCBP2	2	NCBP2 [cytosol] (R-HSA-162458) NCBP2 [nucleoplasm] (R-HSA-51463)	0.643	3
UniProt:Q9Y2W1 THRAP3	1	THRAP3 [nucleoplasm] (R-HSA-8932115)	0.564	2
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.527	4
UniProt:Q13838 DDX39B	2	DDX39B [nucleoplasm] (R-HSA-8849139) DDX39B [cytosol] (R-HSA-9715154)	0.527	3
UniProt:P09651 HNRNPA1	2	HNRNPA1 [nucleoplasm] (R-HSA-71927) HNRNPA1 [cytosol] (R-HSA-9727902)	0.527	2
UniProt:P62249 RPS16	2	RPS16 [cytosol] (R-HSA-72337) RPS16 [nucleoplasm] (R-HSA-6791196)	0.527	2
UniProt:Q86V81 ALYREF	2	ALYREF [cytosol] (R-HSA-158482) ALYREF [nucleoplasm] (R-HSA-156649)	0.527	2
UniProt:P11940 PABPC1	1	PABPC1 [cytosol] (R-HSA-156803)	0.527	2
UniProt:P40763 STAT3	12	p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-STAT3 [cytosol] (R-HSA-8982823) p-STAT3 [nucleoplasm] (R-HSA-8983188) Unfolded STAT3 [cytosol] (R-HSA-6813811)	0.512	3