Reactome | SRP72 [cytosol]

SRP72 [cytosol]

Stable Identifier

R-HSA-265069

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O76094 SRP72

Gene Names

SRP72

Chain

initiator methionine:1, chain:2-671

Reference Genes

BioGPS Gene:6731 SRP72

COSMIC (genes):SRP72 SRP72

CTD Gene:6731 SRP72

dbSNP Gene:6731 SRP72

ENSEMBL:ENSG00000174780 SRP72

HGNC:11303 SRP72

KEGG Gene (Homo sapiens):6731 SRP72

Monarch:6731 SRP72

NCBI Gene:6731 SRP72

OMIM:602122 SRP72

UCSC:O76094 SRP72

Reference Transcript

Other Identifiers

0004780286

11743299_at

11743300_a_at

11743301_a_at

16967048

208095_s_at

208800_at

208801_at

208802_at

208803_s_at

2453136

2728228

2728229

2728230

2728231

2728232

2728233

2728236

2728239

2728240

2728243

2728244

2728247

2728248

2728250

2728251

2728252

2728253

2728259

2728260

2728261

2728262

2728263

2728264

2728265

2728266

2728267

2728268

2728269

2728270

2728272

2728273

2981759

31670_s_at

33837_at

3807517

6731

8095230

A_23_P337201

A_32_P174713

A_33_P3233891

GE78962

GO:0003674

GO:0003723

GO:0005047

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005786

GO:0005829

GO:0006605

GO:0006614

GO:0006810

GO:0008150

GO:0008312

GO:0015031

GO:0030911

GO:0032991

GO:0042493

GO:0043022

GO:0043226

GO:0048500

Hs.237825.0.A2_3p_at

Hs.237825.0.A3_3p_at

Hs.237825.0.A4_3p_at

ILMN_1683888

PH_hs_0029466

TC04000332.hg

U81554_at

g3243032_3p_a_at

g4502554_3p_s_at

Participant Of

hasComponent

Signal Recognition Particle [cytosol]

Inferred To

LOC108348180 [cytosol] (Rattus norvegicus)

SRP72 [cytosol] (Bos taurus)

SRP72 [cytosol] (Gallus gallus)

SRP72 [cytosol] (Plasmodium falciparum)

SRP72 [cytosol] (Saccharomyces cerevisiae)

SRP72 [cytosol] (Sus scrofa)

srpa-72 [cytosol] (Caenorhabditis elegans)

srp72 [cytosol] (Danio rerio)

srp72 [cytosol] (Dictyostelium discoideum)

srp72 [cytosol] (Schizosaccharomyces pombe)

srp72 [cytosol] (Xenopus tropicalis)

SRP72_CANFA [cytosol] (Canis familiaris)

Srp72 [cytosol] (Drosophila melanogaster)

Srp72 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_001254651.1, NP_008878.3

OpenTargets

ENSG00000174780

HPA

ENSG00000174780-SRP72

GeneCards

O76094

Ensembl

ENST00000642900, ENSP00000424576, ENSP00000495128, ENSG00000174780, ENST00000510663

PRO

O76094

Orphanet

21599

PDB

5WRV, 5M72, 5M73, 5WRW

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate [ChEBI:16851]	7	PI(3,5)P2 [plasma membrane] (R-ALL-1806224) PI(3,5)P2 [phagophore assembly site membrane] (R-ALL-5692959) PI(3,5)P2 [Golgi membrane] (R-ALL-1806290) PI(3,5)P2 [early endosome membrane] (R-ALL-1806205) PI(3,5)P2 [late endosome membrane] (R-ALL-1806289) PI(3,5)P2 [endoplasmic reticulum membrane] (R-ALL-6809774) PI(3,5)P2 [lysosomal membrane] (R-ALL-5334668)	0.462	2
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate [ChEBI:18348]	6	PI(4,5)P2 [Golgi membrane] (R-ALL-1806165) PI(4,5)P2 [plasma membrane] (R-ALL-179856) PI(4,5)P2 [endoplasmic reticulum membrane] (R-ALL-2023856) PI(4,5)P2 [nucleoplasm] (R-ALL-6810412) PI(4,5)P2 [cytoplasmic vesicle membrane] (R-ALL-8874467) PI(4,5)P2 [early endosome membrane] (R-ALL-8849966)	0.462	2

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