Reactome | SRP72 [cytosol]

SRP72 [cytosol]

Stable Identifier

R-HSA-265069

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O76094 SRP72

Gene Names

SRP72

Chain

initiator methionine:, chain:2-671

Reference Genes

BioGPS Gene:6731 SRP72

COSMIC (genes):SRP72 SRP72

CTD Gene:6731 SRP72

dbSNP Gene:6731 SRP72

ENSEMBL:ENSG00000174780 SRP72

HGNC:11303 SRP72

KEGG:hsa:6731 SRP72

Monarch:6731 SRP72

NCBI Gene:6731 SRP72

OMIM:602122 SRP72

UCSC:O76094 SRP72

Reference Transcript

Other Identifiers

11743299_at

11743300_a_at

11743301_a_at

16967048

208095_PM_s_at

208095_s_at

208263_PM_at

208263_at

208800_PM_at

208800_at

208801_PM_at

208801_at

208802_PM_at

208802_at

208803_PM_s_at

208803_s_at

2453136

2728227

2728228

2728229

2728230

2728231

2728232

2728233

2728234

2728235

2728236

2728237

2728238

2728239

2728240

2728243

2728244

2728246

2728247

2728248

2728249

2728250

2728251

2728252

2728253

2728254

2728256

2728258

2728259

2728260

2728261

2728262

2728263

2728264

2728265

2728266

2728267

2728268

2728269

2728270

2728272

2728273

2981759

31670_s_at

33837_at

3807517

6731

8095230

A_14_P118376

A_23_P337201

A_24_P928436

A_32_P174713

A_33_P3233891

GE78962

GO:0003723

GO:0005047

GO:0005515

GO:0005737

GO:0005783

GO:0005786

GO:0005829

GO:0006614

GO:0008312

GO:0030911

GO:0043022

GO:0043226

GO:0048500

GO:1990904

HMNXSV003010683

Hs.237825.0.A2_3p_at

Hs.237825.0.A3_3p_at

Hs.237825.0.A4_3p_at

ILMN_1683888

PH_hs_0029466

TC04000332.hg

U81554_at

g3243032_3p_a_at

g4502554_3p_s_at

g8924033_3p_at

Participates

as a component of

Signal Recognition Particle [cytosol] (Homo sapiens)

Inferred To

SRP72 [cytosol] (Bos taurus)

SRP72 [cytosol] (Gallus gallus)

SRP72 [cytosol] (Plasmodium falciparum)

SRP72 [cytosol] (Saccharomyces cerevisiae)

SRP72 [cytosol] (Sus scrofa)

srpa-72 [cytosol] (Caenorhabditis elegans)

Ghost homologue of SRP72 [cytosol] (Danio rerio)

srp72 [cytosol] (Dictyostelium discoideum)

srp72 [cytosol] (Schizosaccharomyces pombe)

srp72 [cytosol] (Xenopus tropicalis)

SRP72_CANFA [cytosol] (Canis familiaris)

Srp72 [cytosol] (Drosophila melanogaster)

Srp72 [cytosol] (Mus musculus)

Srp72 [cytosol] (Rattus norvegicus)

Cross References

ENSEMBL

ENSP00000424576, ENST00000510663, ENSP00000495128, ENSG00000174780, ENST00000642900

OpenTargets

ENSG00000174780

GeneCards

SRP72

HPA

ENSG00000174780-SRP72

PRO

O76094

Pharos - Targets

O76094

GlyGen

O76094

Orphanet

SRP72

PDB

5M72, 5WRW, 5M73, 5WRV, 8QVW, 7NFX

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9H9Z2 LIN28A	1	LIN28A [cytosol] (R-HSA-500391)	0.527	3
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.527	4
UniProt:P06748 NPM1	11	NPM1 [cytosol] (R-HSA-3008211) p-S4-NPM1 [cytosol] (R-HSA-6801679) NPM1 [nucleoplasm] (R-HSA-606320) NPM1 [granular component] (R-HSA-9017702) NPM1(1-117)-ALK(1058-1620) fusion [cytosol] (R-HSA-9699834) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9699861) NPM1(1-117)-ALK(1068-1620) fusion [cytosol] (R-HSA-9730697) NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol] (R-HSA-9730703) NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm] (R-HSA-9725010) polySUMO2,3-K263-NPM1 [nucleoplasm] (R-HSA-4086056) monoSUMO1-K263-NPM1 [nucleoplasm] (R-HSA-4086039)	0.527	2
UniProt:P05388 RPLP0	1	RPLP0 [cytosol] (R-HSA-72396)	0.527	2
UniProt:P62753 RPS6	4	RPS6 [cytosol] (R-HSA-72381) p-5S-RPS6 [cytosol] (R-HSA-165727) 3OHR147-RPS6 [cytosol] (R-HSA-9629876) RPS6 [nucleoplasm] (R-HSA-6790606)	0.483	2
UniProt:P48431 SOX2	1	SOX2 [nucleoplasm] (R-HSA-452271)	0.483	2