Reactome | KRTAP10-7 [cytosol]

KRTAP10-7 [cytosol]

Stable Identifier

R-HSA-6810279

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Keratin-associated protein 10-7, KR107_HUMAN

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- Keratinization (Homo sapiens)
  - Formation of hair keratin fibres (Homo sapiens)
    - Keratin associated proteins [cytosol] (Homo sapiens)
      - KRTAP10s [cytosol] (Homo sapiens)
        
        KRTAP10-7 [cytosol] (Homo sapiens)
    - Keratin tonofilament:Keratin associated proteins polymer [cytosol] (Homo sapiens)
      - Keratin tonofilament, KAPs [cytosol] (Homo sapiens)
        
        Keratin associated proteins [cytosol] (Homo sapiens)
        
        KRTAP10s [cytosol] (Homo sapiens)
        
        KRTAP10-7 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:P60409 KRTAP10-7

Gene Names

KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7

Chain

chain:1-370

Reference Genes

BioGPS Gene:386675 KRTAP10-7

COSMIC (genes):KRTAP10-7 KRTAP10-7

CTD Gene:386675 KRTAP10-7

dbSNP Gene:386675 KRTAP10-7

ENSEMBL:ENSG00000272804 KRTAP10-7

HGNC:22970 KRTAP10-7

KEGG:hsa:386675 KRTAP10-7

Monarch:386675 KRTAP10-7

NCBI Gene:386675 KRTAP10-7

UCSC:P60409 KRTAP10-7

Reference Transcript

RefSeq:NM_198689.3 KRTAP10-7

Other Identifiers

11738553_at

16923653

237853_PM_x_at

386675

3923839

3923840

3923841

3923842

3923851

3923852

3923853

3923861

3923877

3923898

3923899

3934575

3934579

3934580

3934587

3934598

3934599

8069146

8070786

A_33_P3293763

GO:0005515

GO:0005829

GO:0005882

GO:0042802

GO:0045095

HMNXSV003035427

Hs.297526.0.A1_3p_at

ILMN_1677392

PH_hs_0034012

TC21000231.hg

Participates

as a member of

KRTAP10s [cytosol] (Homo sapiens)

Inferred To

Krtap10-27 [cytosol] (Mus musculus)

Krtap10-32 [cytosol] (Mus musculus)

Krtap10-26 [cytosol] (Mus musculus)

Krtap10-33 [cytosol] (Mus musculus)

Krtap10-28 [cytosol] (Mus musculus)

LOC100623393 [cytosol] (Sus scrofa)

Krtap10-4 [cytosol] (Mus musculus)

Krtap10-25 [cytosol] (Mus musculus)

Krtap10-30 [cytosol] (Mus musculus)

Krtap10-29 [cytosol] (Mus musculus)

Krtap10-31 [cytosol] (Mus musculus)

Homologues of KRTAP10-7 [cytosol] (Bos taurus)

Homologues of KRTAP10-7 [cytosol] (Mus musculus)

Homologues of KRTAP10-7 [cytosol] (Rattus norvegicus)

Homologues of KRTAP10-7 [cytosol] (Sus scrofa)

Krtap10-24 [cytosol] (Mus musculus)

KRTAP10-8 [cytosol] (Bos taurus)

Krtap10-23 [cytosol] (Mus musculus)

Krtap10-22 [cytosol] (Mus musculus)

Krtap10-9 [cytosol] (Rattus norvegicus)

KRTAP10-7 [cytosol] (Bos taurus)

KRTAP10-7 [cytosol] (Sus scrofa)

Krtap10-10 [cytosol] (Mus musculus)

LOC102160031 [cytosol] (Sus scrofa)

LOC100622826 [cytosol] (Sus scrofa)

LOC100518807 [cytosol] (Sus scrofa)

Krtap10-21 [cytosol] (Mus musculus)

Krtap10-34 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_941962.1

OpenTargets

ENSG00000272804

ENSEMBL

ENST00000609664, ENSP00000476821, ENSG00000272804

GeneCards

KRTAP10-7

HPA

ENSG00000272804-KRTAP10-7

PRO

P60409

Pharos - Targets

P60409

Interactors (46)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43463 SUV39H1	1	SUV39H1 [nucleoplasm] (R-HSA-427517)	0.718	6
UniProt:Q13526 PIN1	2	PIN1 [nucleoplasm] (R-HSA-936016) PIN1 [cytosol] (R-HSA-9626823)	0.718	6
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.718	6
UniProt:O95363 FARS2	1	FARS2(1-?) [mitochondrial matrix] (R-HSA-379565)	0.718	6
UniProt:Q8IW45 NAXD	1	CARKD [mitochondrial matrix] (R-HSA-6806970)	0.718	6
UniProt:Q8WUK0 PTPMT1	1	PTPMT1 [mitochondrial inner membrane] (R-HSA-3446802)	0.718	6
UniProt:Q08426 EHHADH	2	EHHADH [peroxisomal matrix] (R-HSA-400155) EHHADH [cytosol] (R-HSA-9033147)	0.556	3
UniProt:Q9NP91 SLC6A20	2	SLC6A20 [plasma membrane] (R-HSA-352058) SLC6A20 T199M [plasma membrane] (R-HSA-5660705)	0.556	3
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.556	3
UniProt:O96014 WNT11	9	N4GlycoAsn-PalmS WNT11 [extracellular region] (R-HSA-3247797) N4GlycoAsn-PalmS WNT11 [plasma membrane] (R-HSA-3247792) N4GlycoAsn-PalmS WNT11 [Golgi lumen] (R-HSA-3247823) N4GlycoAsn-PalmS WNT11 [endoplasmic reticulum lumen] (R-HSA-3238335) N4GlycoAsn-WNT11 [endoplasmic reticulum lumen] (R-HSA-3238222) WNT11 [endoplasmic reticulum lumen] (R-HSA-3238281) N4GlycoAsn-PalmS WNT11 [endocytic vesicle membrane] (R-HSA-3781987) N4GlycoAsn-PalmS WNT11 [extracellular exosome] (R-HSA-3781980) WNT11 [extracellular region] (R-HSA-517473)	0.556	3
UniProt:Q9Y5Y2 NUBP2	1	NUBP2 [cytosol] (R-HSA-2564767)	0.556	3
UniProt:P49638 TTPA	1	TTPA [cytosol] (R-HSA-2980979)	0.556	3
UniProt:P41222 PTGDS	1	PTGDS [endoplasmic reticulum membrane] (R-HSA-2142814)	0.556	3
UniProt:Q92835 INPP5D	2	INPP5D [cytosol] (R-HSA-197940) p-Y-INPP5D [cytosol] (R-HSA-9680730)	0.556	3
UniProt:O75461 E2F6	2	E2F6 [nucleoplasm] (R-HSA-8953089) p-S12-E2F6 [nucleoplasm] (R-HSA-9007536)	0.556	3
UniProt:Q9H2F3 HSD3B7	1	HSD3B7 [endoplasmic reticulum membrane] (R-HSA-193441)	0.556	3
UniProt:P78368 CSNK1G2	2	CSNK1G2 [plasma membrane] (R-HSA-205718) CSNK1G2 [cytosol] (R-HSA-429696)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:Q9NQS3 NECTIN3	1	PVRL3 [plasma membrane] (R-HSA-449762)	0.556	3
UniProt:Q9UBV7 B4GALT7	4	B4GALT7 A186D [Golgi membrane] (R-HSA-3621785) B4GALT7 L206P [Golgi membrane] (R-HSA-3621790) B4GALT7 R270C [Golgi membrane] (R-HSA-3621734) B4GALT7 [Golgi membrane] (R-HSA-1889950)	0.556	3
UniProt:Q92608 DOCK2	3	DOCK2 [specific granule lumen] (R-HSA-6799558) DOCK2 [extracellular region] (R-HSA-6806310) DOCK2 [cytosol] (R-HSA-200938)	0.556	5
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	5
UniProt:Q96HC4 PDLIM5	1	PDLIM5 [cytosol] (R-HSA-6794246)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:P62857 RPS28	2	RPS28 [cytosol] (R-HSA-72365) RPS28 [nucleoplasm] (R-HSA-6791202)	0.556	3
UniProt:P02545 LMNA	3	LMNA(1-567)-p-RAF1(279-648) fusion [cytosol] (R-HSA-6802537) LMNA(1-567)-RAF1(279-648) fusion [cytosol] (R-HSA-6802399) LMNA(1-646) [nuclear envelope] (R-HSA-535479)	0.556	3
UniProt:Q96SZ4 ZSCAN10	1	ZSCAN10 [nucleoplasm] (R-HSA-480774)	0.556	3
UniProt:Q8TAQ5 ZNF420	2	ZNF420 [nucleoplasm] (R-HSA-1247509) p-S68-ZNF420 [nucleoplasm] (R-HSA-6799095)	0.556	3
UniProt:Q14554 PDIA5	1	PDIA5 [endoplasmic reticulum membrane] (R-HSA-535514)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	9
UniProt:P51959 CCNG1	1	CCNG1 [nucleoplasm] (R-HSA-6792489)	0.556	3
UniProt:Q9UBK9 UXT	1	UXT [nucleoplasm] (R-HSA-9007484)	0.556	3
UniProt:P15151 PVR	1	PVR [plasma membrane] (R-HSA-420600)	0.556	3
UniProt:Q92692 NECTIN2	1	PVRL2 [plasma membrane] (R-HSA-419006)	0.556	3
UniProt:O75386 TULP3	1	TULP3 [cilium] (R-HSA-5610445)	0.556	3
UniProt:Q15077 P2RY6	1	P2RY6 [plasma membrane] (R-HSA-417924)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	5
UniProt:Q9NSA3 CTNNBIP1	1	CTNNBIP1 [nucleoplasm] (R-HSA-3772388)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:P43353 ALDH3B1	3	ALDH3B1 [plasma membrane] (R-HSA-5696096) ALDH3B1 [secretory granule membrane] (R-HSA-6801023) ALDH3B1 [specific granule membrane] (R-HSA-6799510)	0.556	3
UniProt:Q9UGY1 NOL12	1	NOL12 [nucleoplasm] (R-HSA-6791195)	0.556	3
UniProt:Q13875 MOBP	1	MOBP [cytosol] (R-HSA-9022884)	0.556	3
UniProt:Q92824 PCSK5	2	PCSK5(115-1860) [Golgi lumen] (R-HSA-166558) PCSK5 [extracellular region] (R-HSA-6784682)	0.556	3
UniProt:Q49AN0 CRY2	5	CRY2 [cytosol] (R-HSA-400255) p-S-CRY2 [nucleoplasm] (R-HSA-400328) p-S-CRY2 [cytosol] (R-HSA-400305) K48polyUb-K126,p-S-CRY2 [cytosol] (R-HSA-9932882) K48polyUb-K,p-S-CRY2 [nucleoplasm] (R-HSA-517935)	0.556	3
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:P40763 STAT3	12	p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) p-STAT3 [cytosol] (R-HSA-8982823) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-S727-STAT3 [cytosol] (R-HSA-198705) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-STAT3 [nucleoplasm] (R-HSA-8983188) Unfolded STAT3 [cytosol] (R-HSA-6813811)	0.488	2

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