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BANF1 [cytosol]
Stable Identifier
R-HSA-175371
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
BAF protein
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
PP2A dephosphorylates BANF1 (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Early Phase of HIV Life Cycle (Homo sapiens)
Integration of provirus (Homo sapiens)
Formation of Pre-Integration Complex (PIC) (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Import of PIC to the Host Nucleus (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Vpr:importin-alpha complex [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Integrase binds viral DNA ends (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Terminal (3' end) cleavage of viral DNA (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
APOBEC3G mediated resistance to HIV-1 infection (Homo sapiens)
Association of APOBEC3G with Gag (Homo sapiens)
APOBEC3G:HIV-1PIC [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Interactions of Vpr with host cellular proteins (Homo sapiens)
Vpr-mediated nuclear import of PICs (Homo sapiens)
Interaction of Vpr with importin alpha (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Vpr:importin-alpha complex [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
Vpr binds nucleoporins (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
PIC anchored to the NPC [nuclear envelope] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75531 BANF1
Gene Names
BANF1, BAF, BCRG1
Chain
initiator methionine:1, chain:1-89, chain:2-89
Reference Genes
BioGPS Gene:8815 BANF1
COSMIC (genes):BANF1 BANF1
CTD Gene:8815 BANF1
dbSNP Gene:8815 BANF1
ENSEMBL:ENSG00000175334.8 BANF1
HGNC:17397 BANF1
KEGG Gene (Homo sapiens):8815 BANF1
Monarch:8815 BANF1
NCBI Gene:8815 BANF1
OMIM:603811 BANF1
UCSC:O75531 BANF1
Reference Transcript
RefSeq:NM_003860.3 BANF1
RefSeq:NM_001143985.1 BANF1
RefSeq:XM_017018515.1 BANF1
RefSeq:XM_017018514.1 BANF1
Other Identifiers
0003390242
11716884_a_at
11716885_x_at
11753836_x_at
11754130_a_at
11754131_x_at
11757065_x_at
16727224
210125_PM_s_at
210125_s_at
2603240
2603241
2603247
2603249
3335886
3335887
3335888
3335890
3335891
3335892
3335893
38663_at
7941501
8180260
8815
A_23_P47208
GE61222
GE86482
GO:0000278
GO:0000785
GO:0000793
GO:0002376
GO:0003677
GO:0003690
GO:0005515
GO:0005622
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006979
GO:0007059
GO:0007084
GO:0008022
GO:0009615
GO:0010836
GO:0015074
GO:0019899
GO:0030261
GO:0032480
GO:0036211
GO:0042802
GO:0042803
GO:0043226
GO:0045071
GO:0045824
GO:0047485
GO:0061024
GO:0097726
GO:0098542
GO:0140014
HMNXSV003039288
ILMN_1749243
ILMN_2179837
PH_hs_0020150
TC11000650.hg
g3002950_3p_s_at
Participates
as a component of
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
BANF1 [cytosol] (Homo sapiens)
as an input of
Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 (Homo sapiens)
Other forms of this molecule
p-T2,T3,S4-BANF1 [nucleoplasm]
BANF1 [nucleoplasm]
p-T2,T3,S4-BANF1 [cytosol]
Inferred To
BANF1 [cytosol]
(Bos taurus)
BANF1 [cytosol]
(Canis familiaris)
BANF1 [cytosol]
(Gallus gallus)
BANF1 [cytosol]
(Sus scrofa)
baf-l [cytosol]
(Xenopus tropicalis)
Banf1 [cytosol]
(Mus musculus)
Banf1 [cytosol]
(Rattus norvegicus)
baf [cytosol]
(Drosophila melanogaster)
banf1 [cytosol]
(Danio rerio)
baf-1 [cytosol]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_003851.1
,
XP_016874004.1
,
NP_001137457.1
,
XP_016874003.1
OpenTargets
ENSG00000175334
HPA
ENSG00000175334-BANF1
GeneCards
O75531
Ensembl
ENSG00000175334
,
ENSP00000433760
,
ENST00000527348
,
ENSP00000416128
,
ENSP00000432867
,
ENSP00000310275
,
ENST00000312175
,
ENST00000445560
,
ENST00000533166
PRO
O75531
Pharos - Targets
O75531
Orphanet
20477
PDB
6GHD
,
6USD
,
2EZZ
,
6USB
,
1CI4
,
6URN
,
1QCK
,
6URL
,
2EZY
,
2EZX
,
6US7
,
7NDY
,
6URK
,
6UNT
,
6URJ
,
6URZ
,
6US1
,
6RPR
,
6URE
,
7ABM
,
2ODG
,
6US0
,
6URR
,
6USI
,
2BZF
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50402 EMD
4
EMD [nuclear envelope]
(R-HSA-201573)
EMD [cytosol]
(R-HSA-9613988)
EMD [endoplasmic reticulum membrane]
(R-HSA-9613998)
EMD [endosome membrane]
(R-HSA-9715092)
0.938
13
UniProt:O75531 BANF1
4
p-T2,T3,S4-BANF1 [nucleoplasm]
(R-HSA-2993896)
BANF1 [nucleoplasm]
(R-HSA-175030)
BANF1 [cytosol]
(R-HSA-175371)
p-T2,T3,S4-BANF1 [cytosol]
(R-HSA-2995375)
0.618
3
UniProt:Q9H503-2 BANF2
0.556
3
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