Reactome | ECH1 [mitochondrial matrix]

ECH1 [mitochondrial matrix]

Stable Identifier

R-HSA-9838037

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

fullName evidence="8"Delta, ECH1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13011 ECH1

Gene Names

ECH1

Chain

transit peptide:1-33, chain:34-328

Reference Genes

BioGPS Gene:1891 ECH1

COSMIC (genes):ECH1 ECH1

CTD Gene:1891 ECH1

dbSNP Gene:1891 ECH1

ENSEMBL:ENSG00000104823 ECH1

HGNC:3149 ECH1

Monarch:1891 ECH1

NCBI Gene:1891 ECH1

OMIM:600696 ECH1

UCSC:Q13011 ECH1

Reference Transcript

RefSeq:NM_001398.2 ECH1

Other Identifiers

11757030_at

16872039

1891

200789_PM_at

200789_at

32756_at

3861582

3861583

3861584

3861585

3861586

3861587

3861588

3861589

3861590

3861591

3861592

3861593

3861594

3861595

3861596

3861597

3861598

3861606

3861607

3861608

3861609

3861610

3861611

3861612

3861613

3861614

3861615

3861616

73116_s_at

8036602

A_23_P153853

GE81017

GO:0003824

GO:0005515

GO:0005739

GO:0005759

GO:0005777

GO:0005782

GO:0005829

GO:0006629

GO:0006631

GO:0006635

GO:0016020

GO:0016853

GO:0043226

GO:0051750

GO:0070062

HMNXSV003056039

ILMN_1653115

PH_hs_0011591

TC19002698.hg

U16660_at

g4503446_3p_s_at

Participates

as a member of

Other forms of this molecule

ECH1(1-328) [peroxisomal matrix]

ECH1(1-328) [cytosol]

Inferred To

ECH1 [mitochondrial matrix] (Bos taurus)

ECH1 [mitochondrial matrix] (Caenorhabditis elegans)

ECH1 [mitochondrial matrix] (Dictyostelium discoideum)

ECH1 [mitochondrial matrix] (Gallus gallus)

ECH1 [mitochondrial matrix] (Mus musculus)

ECH1 [mitochondrial matrix] (Rattus norvegicus)

ECH1 [mitochondrial matrix] (Sus scrofa)

Dmel\CG9577 [mitochondrial matrix] (Drosophila melanogaster)

ech1 [mitochondrial matrix] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSP00000489530, ENSP00000221418, ENST00000221418, ENST00000634245

OpenTargets

ENSG00000104823

HPA

ENSG00000104823-ECH1

PRO

Q13011

Pharos - Targets

Q13011

GlyGen

Q13011

HMDB Protein

HMDBP03124

PDB

8SK6, 2VRE

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.666	4
UniProt:Q16659 MAPK6 gene	6	p-3S,T MAPK6 [nucleoplasm] (R-HSA-5692665) MAPK6 [nucleoplasm] (R-HSA-5692686) p-S189 MAPK6 [nucleoplasm] (R-HSA-5687015) p-S189 MAPK6 [cytosol] (R-HSA-5687019) MAPK6 [cytosol] (R-HSA-5686979) ub-MAPK6 [cytosol] (R-HSA-5687000)	0.643	3
UniProt:P26641 EEF1G	3	EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] (R-HSA-9710850) EEF1G(1-343)-ALK(1106-1620) fusion [cytosol] (R-HSA-9710839) EEF1G [cytosol] (R-HSA-156925)	0.553	2
UniProt:P46940 IQGAP1	3	IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [plasma membrane] (R-HSA-381681)	0.527	2
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.527	2
UniProt:Q13114 TRAF3	4	K63polyUb-TRAF3 [cytosol] (R-HSA-936402) TRAF3 [cytosol] (R-HSA-914241) K48polyUb-TRAF3 [cytosol] (R-HSA-936556) TRAF3 R118W [cytosol] (R-HSA-5602321)	0.527	2
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.508	2
UniProt:P40763 STAT3	12	p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-STAT3 [cytosol] (R-HSA-8982823) p-STAT3 [nucleoplasm] (R-HSA-8983188) Unfolded STAT3 [cytosol] (R-HSA-6813811)	0.508	2

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