Reactome | UniProt:P04626 ERBB2

UniProt:P04626 ERBB2

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

ERBB2_HUMAN, B2RZG3, B4DHN3, Q14256, Q6LDV1, Q9UMK4, X5D2V5

List of interactors in Reactome

Interactors (33)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.954	25
P04626	1	ERBB2 [plasma membrane] (R-HSA-372889)	0.926	12
P62993	1	GRB2 [cytosol] (R-HSA-8983328)	0.916	8
P07900	1	HSP90AA1 [cytosol] (R-HSA-192864)	0.856	6
P29353	2	p-Y427-SHC1 [cytosol] (R-HSA-74684) SHC1 [cytosol] (R-HSA-74680)	0.821	16
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.793	5
Q14451	1	GRB7 [cytosol] (R-HSA-204819)	0.779	5
P40763	6	p-S727-STAT3 [cytosol] (R-HSA-198705) p-STAT3 [cytosol] (R-HSA-8982823) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044)	0.775	9
P27986	1	PIK3R1 [cytosol] (R-HSA-74789)	0.759	12
Q96JA1	1	LRIG1 [plasma membrane] (R-HSA-197745)	0.748	7
P12931	5	MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408) MyrG-SRC [plasma membrane] (R-HSA-8876922) p-Y419-SRC [cytosol] (R-HSA-8964276) p-Y419-SRC [nucleoplasm] (R-HSA-8937690) SRC [cytosol] (R-HSA-9628701)	0.708	11
P11021	2	HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [extracellular region] (R-HSA-351322)	0.659	3
Q13882	4	p-Y342,Y447-PTK6 [cytosol] (R-HSA-8849103) p-Y342-PTK6 [cytosol] (R-HSA-8848007) p-Y342-PTK6 [nucleoplasm] (R-HSA-8848937) PTK6 [cytosol] (R-HSA-8848000)	0.628	4
P46940	1	IQGAP1 [plasma membrane] (R-HSA-381681)	0.602	5
P20936	1	RASA1 [cytosol] (R-HSA-186833)	0.592	8
Q05209	1	PTPN12 [cytosol] (R-HSA-432933)	0.592	4
Q06124	2	PTPN11 [cytosol] (R-HSA-162563) PTPN11 [nucleoplasm] (R-HSA-8937745)	0.592	3
P42679	1	MATK [cytosol] (R-HSA-1433581)	0.59	2
P31948	1	STIP1 [cytosol] (R-HSA-443857)	0.573	2
O75791	1	GRAP2 [cytosol] (R-HSA-202367)	0.571	2
P16885	5	p-PLCG2 [plasma membrane] (R-HSA-114602) p-Y753,Y759-PLCG2 [cytosol] (R-HSA-5607631) p-Y753,Y759-PLCG2 [plasma membrane] (R-HSA-5607640) PLCG2 [cytosol] (R-HSA-984806) PLCG2 [plasma membrane] (R-HSA-114601)	0.571	3
P42224	4	p-STAT1 [cytosol] (R-HSA-8950418) p-Y701-STAT1 [cytosol] (R-HSA-8951202) p-Y701-STAT1 [cytosol] (R-HSA-3132766) STAT1 [cytosol] (R-HSA-629622)	0.571	3
P27824	1	CANX [endoplasmic reticulum lumen] (R-HSA-195906)	0.569	3
O95602	1	POLR1A [nucleoplasm] (R-HSA-63494)	0.567	16
Q14974	2	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714)	0.567	14
O14980	2	XPO1 [cytosol] (R-HSA-165539) XPO1 [nucleoplasm] (R-HSA-165529)	0.564	3
P06241	2	FYN [cytosol] (R-HSA-200917) p-Y531-FYN [cytosol] (R-HSA-391819)	0.558	2
Q99952	1	PTPN18 [cytosol] (R-HSA-8864101)	0.558	6
Q9UBN7	2	HDAC6 [cytosol] (R-HSA-5324660) HDAC6 [nucleoplasm] (R-HSA-351589)	0.553	2
P60709	2	ACTB(1-375) [cytosol] (R-HSA-201861) ACTB(1-375) [nucleoplasm] (R-HSA-3321990)	0.537	10
Q05397	4	PTK2 [cytosol] (R-HSA-201621) PTK2(1-772) [cytosol] (R-HSA-202827) PTK2(773-1052) [cytosol] (R-HSA-202829) pY-PTK2 [cytosol] (R-HSA-9632393)	0.536	2
Q92504	1	SLC39A7 [endoplasmic reticulum membrane] (R-HSA-442363)	0.527	2
P49792	3	monoSUMO1-K2592,K2650,K2723-RANBP2 [nuclear envelope] (R-HSA-4551599) polySUMO2-K2652,K2725-RANBP2 [nuclear envelope] (R-HSA-4551720) RANBP2 [nuclear envelope] (R-HSA-2993756)	0.463	3