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BANF1 [nucleoplasm]
Stable Identifier
R-HSA-175030
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
BAF protein
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
BANF1 binds chromatin, EMD/TMPO/LEMD3/LEMD2 and lamins (Homo sapiens)
EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Mitotic Prophase (Homo sapiens)
Nuclear Envelope Breakdown (Homo sapiens)
VRK1/VRK2 phosphorylate BANF1 (Homo sapiens)
EMD/TMPO/LEMD3/LEMD2:Lamin filaments:BANF1:Chromatin [nuclear envelope] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Early Phase of HIV Life Cycle (Homo sapiens)
Integration of provirus (Homo sapiens)
1-LTR circle formation (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
viral PIC proteins [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
2-LTR circle formation (Homo sapiens)
Association of Ku heterodimer with viral DNA ends (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
viral PIC proteins [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Autointegration results in viral DNA circles (Homo sapiens)
Suicidal integration leading to inverted circle formation (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
viral PIC proteins [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Suicidal integration leading to smaller circles of viral DNA (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
viral PIC proteins [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Import of PIC to the Host Nucleus (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Integration of viral DNA into host genomic DNA (Homo sapiens)
Target DNA binding (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
viral PIC proteins [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75531 BANF1
Gene Names
BANF1, BAF, BCRG1
Chain
chain:1-89, initiator methionine:, chain:2-89
Reference Genes
BioGPS Gene:8815 BANF1
COSMIC (genes):BANF1 BANF1
CTD Gene:8815 BANF1
dbSNP Gene:8815 BANF1
ENSEMBL:ENSG00000175334 BANF1
ENSEMBL_homo_sapiens_GENE:ENSG00000175334.8 BANF1
HGNC:17397 BANF1
KEGG Gene (Homo sapiens):8815 BANF1
Monarch:8815 BANF1
NCBI Gene:8815 BANF1
OMIM:603811 BANF1
UCSC:O75531 BANF1
Reference Transcript
RefSeq:NM_003860.3 BANF1
RefSeq:NM_001143985.1 BANF1
RefSeq:XM_017018515.1 BANF1
RefSeq:XM_017018514.1 BANF1
Other Identifiers
11716884_a_at
11716885_x_at
11753836_x_at
11754130_a_at
11754131_x_at
11757065_x_at
16727224
210125_PM_s_at
210125_s_at
2603240
2603241
2603247
2603249
3335886
3335887
3335888
3335890
3335891
3335892
3335893
38663_at
7941501
8180260
8815
A_23_P47208
GE61222
GE86482
GO:0000278
GO:0000785
GO:0000793
GO:0002376
GO:0003677
GO:0003690
GO:0005515
GO:0005634
GO:0005635
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0006325
GO:0006979
GO:0007084
GO:0009615
GO:0010836
GO:0015074
GO:0023052
GO:0032480
GO:0042802
GO:0042803
GO:0043226
GO:0045071
GO:0045824
GO:0061024
GO:0098542
GO:0140014
GO:0160049
HMNXSV003039288
ILMN_1749243
ILMN_2179837
PH_hs_0020150
TC11000650.hg
g3002950_3p_s_at
Participates
as a component of
viral PIC proteins [nucleoplasm] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm] (Homo sapiens)
BANF1 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
BANF1 [cytosol]
p-T2,T3,S4-BANF1 [cytosol]
p-T2,T3,S4-BANF1 [nucleoplasm]
Inferred To
Banf1 [nucleoplasm]
(Mus musculus)
Banf1 [nucleoplasm]
(Rattus norvegicus)
BANF1 [nucleoplasm]
(Bos taurus)
BANF1 [nucleoplasm]
(Canis familiaris)
BANF1 [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
XP_016874004.1
,
NP_001137457.1
,
XP_016874003.1
,
NP_003851.1
OpenTargets
ENSG00000175334
HPA
ENSG00000175334-BANF1
GeneCards
O75531
Ensembl
ENST00000533166
,
ENSP00000416128
,
ENST00000445560
,
ENSG00000175334
,
ENST00000312175
,
ENSP00000432867
,
ENSP00000310275
,
ENST00000527348
,
ENSP00000433760
PRO
O75531
Pharos - Targets
O75531
Orphanet
20477
PDB
6USD
,
6URL
,
6URN
,
6USI
,
2BZF
,
6URR
,
6GHD
,
2ODG
,
7ABM
,
1CI4
,
6US1
,
6URZ
,
6US0
,
6URE
,
1QCK
,
2EZZ
,
6US7
,
7NDY
,
6RPR
,
7Z21
,
2EZY
,
6URJ
,
2EZX
,
6USB
,
6UNT
,
6URK
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50402 EMD
4
EMD [nuclear envelope]
(R-HSA-201573)
EMD [cytosol]
(R-HSA-9613988)
EMD [endoplasmic reticulum membrane]
(R-HSA-9613998)
EMD [endosome membrane]
(R-HSA-9715092)
0.938
13
UniProt:Q6UXZ0 TMIG1
0.637
7
UniProt:O75531 BANF1
4
BANF1 [cytosol]
(R-HSA-175371)
p-T2,T3,S4-BANF1 [cytosol]
(R-HSA-2995375)
p-T2,T3,S4-BANF1 [nucleoplasm]
(R-HSA-2993896)
BANF1 [nucleoplasm]
(R-HSA-175030)
0.618
3
UniProt:Q9H503-2 BANF2
0.556
3
UniProt:Q96PV0 SYNGAP1
1
SYNGAP1 [cytosol]
(R-HSA-5658217)
0.527
5
UniProt:Q04206 RELA
6
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
polySUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
RELA [cytosol]
(R-HSA-168172)
RELA [nucleoplasm]
(R-HSA-177676)
0.463
3
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