MAPK1

Stable Identifier
R-HSA-199960
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
ERK2, Mitogen-activated protein kinase 1 (EC 2.7.1.-) (Extracellular signal- regulated kinase 2) (ERK-2) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1), Mitogen-activated protein kinase 1 , Extracellular signal-regulated kinase 2, Mitogen-activated protein kinase 2, MAP kinase 2, MAPK 2, p42-MAPK, ERT1
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
MAPK1, ERK2, PRKM1, PRKM2
Chain
initiator methionine:1, chain:2-360
Other Identifiers
0000580471
0002850739
0003990647
04150+2.7.11.24
11715841_at
11715842_a_at
11715843_at
11738871_a_at
11738872_x_at
11751223_a_at
11751224_x_at
11753379_a_at
1552263_at
1552264_a_at
16932831
1PME
1TVO
1WZY
208351_s_at
212271_at
224620_at
224621_at
2OJG
2OJI
2OJJ
2Y9Q
30069
3954239
3954240
3954241
3954242
3954243
3954244
3954245
3954246
3954248
3954249
3954252
3954256
3954257
3954261
3954262
3954264
3954266
3954273
3954274
3995
3D42
3D44
3I5Z
3I60
3SA0
3TEI
3W55
4229
45715_at
4FMQ
4FUX
4FUY
4FV0
4FV1
4FV2
4FV3
4FV4
4FV5
4FV6
4FV7
4FV8
4FV9
4G6N
4G6O
4H3P
4H3Q
4IZ5
4IZ7
4IZA
4N0S
4NIF
4O6E
4QP1
4QP2
4QP3
4QP4
4QP6
4QP7
4QP8
4QP9
4QPA
4QTA
4QTE
4XJ0
4ZXT
4ZZM
4ZZN
4ZZO
55528_at
5594
5700
5AX3
5BUE
5BUI
5BUJ
5BVD
5BVE
5BVF
5K4I
5LCJ
5LCK
5NGU
5NHF
5NHH
5NHJ
5NHL
5NHO
5NHP
5NHV
5V60
5V61
5V62
8074791
976_s_at
A_23_P257895
A_24_P237265
AAA58459
AAH17832
ABD60303
ABF47102
ABY87541
AGC09596
AP000553
AP000554
AP000555
BC017832
CAA77752
CAA77753
CAB004229
CCDS13795
CH471095
DQ399292
DQ508104
EAW59479
EAW59480
EAW59481
EAW59482
ENSG00000100030
ENSP00000215832
ENSP00000381803
ENSP00000440842
ENST00000215832
ENST00000398822
ENST00000544786
EntrezGene:5594
EU332852
g4506086_3p_a_at
GE476071
GE534117
GE56878
GE86009
GO:0000003
GO:0000165
GO:0000166
GO:0000187
GO:0000902
GO:0001784
GO:0002376
GO:0003674
GO:0003677
GO:0004672
GO:0004674
GO:0004707
GO:0004708
GO:0004871
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005764
GO:0005768
GO:0005769
GO:0005770
GO:0005773
GO:0005794
GO:0005815
GO:0005819
GO:0005829
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006259
GO:0006351
GO:0006355
GO:0006412
GO:0006464
GO:0006468
GO:0006605
GO:0006810
GO:0006913
GO:0006915
GO:0006935
GO:0006950
GO:0006974
GO:0007010
GO:0007049
GO:0007165
GO:0007267
GO:0007268
GO:0007411
GO:0007507
GO:0007611
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008353
GO:0008543
GO:0009058
GO:0009636
GO:0009790
GO:0009887
GO:0010628
GO:0010800
GO:0014032
GO:0014066
GO:0015966
GO:0016020
GO:0016032
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0019233
GO:0019858
GO:0019899
GO:0019901
GO:0019902
GO:0030154
GO:0030168
GO:0030278
GO:0030335
GO:0030424
GO:0030641
GO:0030878
GO:0031143
GO:0031410
GO:0031435
GO:0031647
GO:0031663
GO:0032212
GO:0032496
GO:0032839
GO:0032872
GO:0032991
GO:0033160
GO:0033598
GO:0034198
GO:0034614
GO:0034641
GO:0035094
GO:0035556
GO:0035578
GO:0038095
GO:0038096
GO:0038127
GO:0040011
GO:0042473
GO:0042592
GO:0042802
GO:0043167
GO:0043204
GO:0043226
GO:0043312
GO:0043330
GO:0043627
GO:0044281
GO:0044403
GO:0045596
GO:0045727
GO:0045893
GO:0048538
GO:0048646
GO:0048856
GO:0048870
GO:0050852
GO:0050853
GO:0050877
GO:0051090
GO:0051276
GO:0051403
GO:0051493
GO:0051973
GO:0060020
GO:0060291
GO:0060324
GO:0060425
GO:0060440
GO:0060716
GO:0061308
GO:0070371
GO:0070849
GO:0071276
GO:0071310
GO:0071356
GO:0072584
GO:0072686
GO:0090170
GO:0097011
GO:1900034
GO:1903351
GO:1904355
GO:1904813
GO:2000641
HGNC:6871
HPA003995
HPA005700
HPA030069
Hs.324473.2.S1_3p_at
Hs.66151.0.S1_3p_at
Hs.66151.0.S2_3p_at
Hs2.324473.2.S1_3p_at
ILMN_1665276
ILMN_1706677
ILMN_1767320
ILMN_2235283
IPR000719
IPR003527
IPR008271
IPR008349
IPR011009
IPR017441
JX512449
LRG_786
LRG_786t1
LRG_786t2
M84489
MAPK1
MAPK1-201
MAPK1-202
MAPK1-204
MIM:176948
NM_002745
NM_138957
NP_002736
NP_620407
PF00069
PH_hs_0016141
PH_hs_0039033
PR01770
Q1HBJ4
SM00220
TC22000547.hg
uc002zvn.4
uc002zvo.4
uc010gtk.2
UPI000000104F
UPI00005A4AF1
Z11694
Z11695
Z11695_at
Participant Of
Other forms of this molecule
Inferred To
Cross References
ZINC - World Drugs
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Metabolites
GeneCards
BRENDA (Homo sapiens)
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (42)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P35236 PTPN7  1 0.775 6
 UniProt:Q15349 RPS6KA2  6 0.709 6
 UniProt:P51812 RPS6KA3  6 0.678 3
 UniProt:Q16539-3 MAPK14      0.656 5
 UniProt:P14921 ETS1  2 0.641 3
 UniProt:Q15121 PEA15  1 0.635 3
 UniProt:Q13115 DUSP4  1 0.635 3
 UniProt:P02687 MBP      0.623 2
 UniProt:Q15256 PTPRR      0.621 3
 UniProt:P29353-2 SHC1  6 0.618 4
 UniProt:P35813 PPM1A  2 0.611 19
 UniProt:P28482 MAPK1  7 0.609 3
 UniProt:Q02750 MAP2K1  7 0.609 2
 UniProt:Q9Y296 TRAPPC4  2 0.581 3
 UniProt:Q12913 PTPRJ  2 0.578 7
 UniProt:P27361 MAPK3  4 0.564 3
 UniProt:P32121 ARRB2  2 0.564 3
 UniProt:Q05922  1 0.558 2
 UniProt:P28562 DUSP1  1 0.544 3
 UniProt:Q7L5N1 COPS6  2 0.544 2
 UniProt:Q16690 DUSP5  1 0.543 3
 UniProt:Q9U1H0 CIC      0.527 2
 UniProt:P06239 LCK  4 0.524 2
 UniProt:P53004 BLVRA  1 0.499 2
 IntAct:EBI-11957986 HOMEZ      0.488 2
 UniProt:P62487 POLR2G  1 0.488 2
 UniProt:Q9BUB5 MKNK1  1 0.488 4
 UniProt:O76064 RNF8  1 0.488 2
 UniProt:Q6NYC8 PPR18      0.488 2
 UniProt:P35548 MSX2  1 0.488 2
 UniProt:Q99750 MDFI      0.488 2
 UniProt:Q15256-5 PTPRR      0.488 2
 IntAct:EBI-12903728 FRS2      0.488 2
 UniProt:Q9UPG8 PLAL2      0.488 2
 UniProt:P25786 PSMA1  2 0.488 2
 UniProt:Q9BRK4 LZTS2      0.488 2
 UniProt:Q08117-2 AES      0.488 2
 UniProt:B2RXF5 ZBT42      0.488 2
 UniProt:Q15025 TNIP1  1 0.488 2
 UniProt:P61764 STXBP1  2 0.488 2
 UniProt:P10415 BCL2  1 0.488 2
 UniProt:P46531 NOTCH1  60 0.462 2