Reactome | RABGAP1 [cytosol]

RABGAP1 [cytosol]

Stable Identifier

R-HSA-8854144

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Rab GTPase-activating protein 1, RBGP1_HUMAN, TBC1D11, GAPCenA

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y3P9 RABGAP1

Gene Names

RABGAP1, HSPC094

Chain

chain:1-1069

Reference Genes

BioGPS Gene:23637 RABGAP1

COSMIC (genes):RABGAP1 RABGAP1

CTD Gene:23637 RABGAP1

dbSNP Gene:23637 RABGAP1

ENSEMBL:ENSG00000011454 RABGAP1

HGNC:17155 RABGAP1

KEGG Gene (Homo sapiens):23637 RABGAP1

Monarch:23637 RABGAP1

NCBI Gene:23637 RABGAP1

OMIM:615882 RABGAP1

UCSC:Q9Y3P9 RABGAP1

Reference Transcript

Other Identifiers

0004810451

11743684_a_at

11743685_a_at

11749520_a_at

17088838

204028_s_at

213313_at

23637

3188303

3188309

3188310

3188319

3188320

3188321

3188324

3188325

3188327

3188329

3188331

3188332

3188333

3188339

3188340

3188342

3188358

3188360

3188362

3188365

3188366

3188368

3188375

3188376

3188381

3188382

3188383

3188385

3188386

3188387

3188388

35289_at

8157700

A_14_P110666

A_21_P0006371

A_24_P252575

A_33_P3411991

GE55202

GO:0003674

GO:0005096

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0005875

GO:0006810

GO:0006886

GO:0007049

GO:0008092

GO:0008150

GO:0015031

GO:0015631

GO:0019899

GO:0030234

GO:0031267

GO:0032991

GO:0043087

GO:0043226

GO:0043547

GO:0090630

HMNXSV003006359

HMNXSV003018934

HMNXSV003022678

ILMN_1724438

ILMN_2061950

PH_hs_0003618

TC09000627.hg

g12232372_3p_a_at

Participates

as a component of

RABGAP1:RAB6:GTP [Golgi membrane] (Homo sapiens)

as an input of

TBC1D11 binds RAB6 (Homo sapiens)

Inferred To

GAPcenA [cytosol] (Drosophila melanogaster)

Homologues of RABGAP1 [cytosol] (Dictyostelium discoideum)

RABGAP1 [cytosol] (Bos taurus)

RABGAP1 [cytosol] (Canis familiaris)

RABGAP1 [cytosol] (Dictyostelium discoideum)

RABGAP1 [cytosol] (Gallus gallus)

RABGAP1 [cytosol] (Plasmodium falciparum)

tbc-11 [cytosol] (Caenorhabditis elegans)

GYP5 [cytosol] (Saccharomyces cerevisiae)

AF310892_3 [cytosol] (Dictyostelium discoideum)

Rabgap1 [cytosol] (Mus musculus)

Rabgap1 [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_036329.3, XP_016870057.1, XP_011516743.1, XP_011516742.1, XP_016870056.1, XP_016870058.1

OpenTargets

ENSG00000011454

HPA

ENSG00000011454-RABGAP1

GeneCards

Q9Y3P9

Ensembl

ENSG00000011454, ENST00000456584, ENST00000373647, ENSP00000362751, ENSP00000414386

PRO

Q9Y3P9

Pharos - Targets

Q9Y3P9

GlyGen

Q9Y3P9

PDB

4NC6

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NRI5 DISC1			0.553	2
UniProt:Q9H0R8 GABARAPL1	3	GABARAPL1 [cytosol] (R-HSA-5671757) GABARAPL1(1-117) [cytosol] (R-HSA-5682659) GABARAPL1 [autophagosome membrane] (R-HSA-5683637)	0.499	2
UniProt:P40763 STAT3	12	Unfolded STAT3 [cytosol] (R-HSA-6813811) p-STAT3 [nucleoplasm] (R-HSA-8983188) p-STAT3 [cytosol] (R-HSA-8982823) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705-STAT3 [cytosol] (R-HSA-8983130) p-Y705-STAT3 [cytosol] (R-HSA-914048) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554)	0.488	2

Cite Us!