2xHC-TXN [cytosol]

Stable Identifier
R-HSA-73668
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Thioredoxin, oxidized, Thioredoxin, ATL-derived factor, ADF, Surface associated sulphydryl protein, SASP
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TXN, TRDX, TRX, TRX1
Chain
initiator methionine:, chain:2-105
Other Identifiers
11715469_s_at
11715470_x_at
11750538_x_at
11753775_x_at
11753804_x_at
17097052
208864_PM_s_at
208864_s_at
3220157
3220158
3220159
3220160
3220162
3220166
3220168
3220174
3220175
36992_at
7295
8163185
A_23_P60248
GE81265
GO:0000122
GO:0003723
GO:0003824
GO:0004791
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006886
GO:0006913
GO:0009314
GO:0015035
GO:0016209
GO:0016491
GO:0023052
GO:0032148
GO:0033138
GO:0036211
GO:0042803
GO:0043226
GO:0043388
GO:0045454
GO:0046826
GO:0047134
GO:0051897
GO:0061692
GO:0070062
GO:0071731
GO:0098754
GO:0098869
GO:0140096
GO:2000170
HMNXSV003001941
HMNXSV003052323
ILMN_1680314
ILMN_2038776
PH_hs_0030018
PH_hs_0040358
TC09001473.hg
X77584_at
g11345419_3p_at
g11345419_3p_s_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
Intra-chain Crosslink via L-cystine (cross-link) at 32 and 35
Coordinate
32
PsiMod Name
PsiMod Definition
A protein modification that effectively cross-links two L-cysteine residues to form L-cystine.
Cross References
OpenTargets
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Interactors (33)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  20 0.785 5
 UniProt:Q9H3M7 TXNIP  2 0.743 8
 UniProt:Q92905 COPS5  2 0.736 9
 UniProt:Q99683 MAP3K5  1 0.677 4
 UniProt:P04406 GAPDH  1 0.675 4
 UniProt:P42574 CASP3  5 0.672 6
 UniProt:D0ZRB2 SLRP      0.633 7
 UniProt:Q99836 MYD88  8 0.602 4
 UniProt:P32119 PRDX2  2 0.564 2
 UniProt:Q7Z699 SPRED1  2 0.556 3
 UniProt:P51608 MECP2      0.556 3
 UniProt:P50570-2 DNM2      0.556 3
 UniProt:Q14114-3 Q141143      0.556 3
 UniProt:Q9BXU3 TX13A      0.556 3
 UniProt:Q96D03 DDT4L      0.556 5
 UniProt:Q9Y605 MOFA1      0.556 3
 UniProt:Q9NZD8 SPG21      0.556 6
 UniProt:P01023 A2M  2 0.556 3
 UniProt:Q8WXH2 JPH3      0.556 3
 UniProt:P37198 NUP62  2 0.556 3
 UniProt:P23560-2 BDNF      0.556 3
 UniProt:P19404 NDUFV2  1 0.556 3
 UniProt:G5E9A7 G5E9A7      0.556 3
 UniProt:Q9GZT8 NIF3L      0.556 3
 UniProt:X5D778 X5D778      0.556 6
 UniProt:Q9UJW9 SRTD3      0.556 3
 UniProt:P12814 ACTN1  3 0.556 3
 UniProt:P19883 FST  1 0.556 3
 UniProt:P31749 AKT1  13 0.556 3
 UniProt:P14136 GFAP  3 0.556 3
 UniProt:P07900 HSP90AA1  8 0.556 3
 UniProt:Q12933 TRAF2  5 0.556 3
 UniProt:P13569 CFTR  17 0.483 12
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