p-5Y-RET [plasma membrane]

Stable Identifier
R-HSA-8854162
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Proto-oncogene tyrosine-protein kinase receptor Ret ecNumber2.7.10.1/ecNumber, RET_HUMAN
Icon
p-5Y-RET [plasma membrane] icon
p-5Y-RET [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P07949 RET
Gene Names
RET, CDHF12, CDHR16, PTC, RET51
Chain
signal peptide:1-28, chain:29-1114, chain:29-707, chain:708-1017
Reference Genes
BioGPS Gene:5979 RET
COSMIC (genes):RET RET
CTD Gene:5979 RET
dbSNP Gene:5979 RET
ENSEMBL:ENSG00000165731 RET
ENSEMBL_homo_sapiens_GENE:ENSG00000165731.21 RET
HGNC:9967 RET
KEGG Gene (Homo sapiens):5979 RET
Monarch:5979 RET
NCBI Gene:5979 RET
OMIM:164761 RET
UCSC:P07949 RET
Reference Transcript
Other Identifiers
11729917_at
11733418_at
11733419_a_at
160028_s_at
16704154
1745_at
1822_at
1823_g_at
1889_s_at
205879_PM_x_at
205879_x_at
211421_PM_s_at
211421_s_at
215771_PM_x_at
215771_x_at
3243848
3243849
3243854
3243855
3243859
3243860
3243861
3243862
3243864
3243865
3243866
3243867
3243868
3243869
3243870
3243871
3243873
3243874
3243875
3243876
3243877
3243878
3243879
3243880
3243881
3243882
3243883
3243884
3243885
3243886
3243887
3243888
3243889
3243890
3243891
3243892
3243893
3243894
3243895
3243897
3243899
3243900
3243901
3243903
5979
7927120
91896_at
A_23_P202245
GE82572
GO:0000165
GO:0000166
GO:0001657
GO:0001755
GO:0001838
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005509
GO:0005515
GO:0005524
GO:0005768
GO:0005769
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006919
GO:0007155
GO:0007156
GO:0007158
GO:0007165
GO:0007169
GO:0007399
GO:0007411
GO:0007497
GO:0009410
GO:0010008
GO:0010628
GO:0010976
GO:0012501
GO:0014042
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030154
GO:0030155
GO:0030182
GO:0030335
GO:0030424
GO:0030425
GO:0031410
GO:0033141
GO:0033619
GO:0033630
GO:0035799
GO:0035860
GO:0036211
GO:0038023
GO:0042551
GO:0043025
GO:0043226
GO:0043235
GO:0043410
GO:0045793
GO:0045893
GO:0048265
GO:0048484
GO:0048856
GO:0048870
GO:0050770
GO:0051897
GO:0060041
GO:0060089
GO:0060384
GO:0061146
GO:0071300
GO:0072300
GO:0097021
GO:0098797
GO:0140096
GO:2001241
Hs.241572.1.S1_3p_s_at
ILMN_1655610
ILMN_1666314
ILMN_1706301
M57464_s_at
PH_hs_0032778
TC10000268.hg
TC10002029.hg
g13279040_3p_a_at
g13279040_3p_s_at
g190699_3p_a_at
Participates
as a component of
Other forms of this molecule
RET [plasma membrane]
Inferred To
phospho-RET [plasma membrane] (Canis familiaris)
phospho-p-5Y-RET [plasma membrane] (Bos taurus)
phospho-p-5Y-RET [plasma membrane] (Gallus gallus)
phospho-p-5Y-RET [plasma membrane] (Mus musculus)
phospho-p-5Y-RET [plasma membrane] (Rattus norvegicus)
phospho-p-5Y-RET [plasma membrane] (Sus scrofa)
Modified Residues
Name
O4'-phospho-L-tyrosine at 905
Coordinate
905
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 981
Coordinate
981
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1062
Coordinate
1062
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1096
Coordinate
1096
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1015
Coordinate
1015
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
GeneCards
HPA
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (13)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P22681 CBL  20 0.697 8
 UniProt:Q9Y490 TLN1  2 0.623 2
 UniProt:Q62985  2 0.621 3
 UniProt:Q7Z3S9 NT2NA      0.556 3
 UniProt:P00533 EGFR  20 0.553 2
 UniProt:Q9HCN8 SDF2L      0.527 2
 UniProt:P22455 FGFR4  12 0.499 2
 UniProt:Q9UM73 ALK  20 0.499 2
 UniProt:Q8NEN9 PDZD8      0.483 2
 UniProt:P40763 STAT3  12 0.483 3
 UniProt:P19174 PLCG1  6 0.483 2
 UniProt:Q9Y2U8 LEMD3  4 0.483 3
 UniProt:Q62077 Plcg1  10 0.482 2
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