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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
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Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
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Analyse gene list
Analyse gene expression
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ATP [mitochondrial matrix]
Stable Identifier
R-ALL-113593
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Adenosine 5'-triphosphate, ATP(4-)
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Drug ADME (Bos taurus)
Aspirin ADME (Bos taurus)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Bos taurus)
ATP [mitochondrial matrix]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
IDH3 complex decarboxylates isocitrate (Bos taurus)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Bos taurus)
OGDH dimer decarboxylates 2-OG (Bos taurus)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Bos taurus)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Bos taurus)
ATPase synthesizes ATP (Bos taurus)
ATPase:ATP [mitochondrial inner membrane] (Bos taurus)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Bos taurus)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Bos taurus)
ATP [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
ME2 tetramer decarboxylates MAL to PYR (Bos taurus)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Bos taurus)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Bos taurus)
Regulation of pyruvate dehydrogenase (PDH) complex (Bos taurus)
PDK isozymes phosphorylate PDHC subunit E1 (Bos taurus)
ATP [mitochondrial matrix]
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Ethanol oxidation (Bos taurus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Bos taurus)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Bos taurus)
Amino Acid conjugation (Bos taurus)
Conjugation of carboxylic acids (Bos taurus)
Conjugation of benzoate with glycine (Bos taurus)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Bos taurus)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Bos taurus)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Bos taurus)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Bos taurus)
ACSM2B-like proteins transform ST to ST-CoA (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Bos taurus)
Branched-chain amino acid catabolism (Bos taurus)
BCKDK phosphorylates BCKDH (Bos taurus)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Bos taurus)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Bos taurus)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Bos taurus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Bos taurus)
ATP [mitochondrial matrix]
Urea cycle (Bos taurus)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PC carboxylates PYR to OA (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Fatty acyl-CoA biosynthesis (Bos taurus)
Synthesis of very long-chain fatty acyl-CoAs (Bos taurus)
ACSF3 ligates CoA-SH to VLCFA (Bos taurus)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Bos taurus)
ACSF2 ligates CoA-SH to MCFA (Bos taurus)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Bos taurus)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Bos taurus)
ATP [mitochondrial matrix]
Ketone body metabolism (Bos taurus)
Synthesis of Ketone Bodies (Bos taurus)
ACSS3 ligates CoA to CH3COO- (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Bos taurus)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Bos taurus)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)
ATP [mitochondrial matrix]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Bos taurus)
ATP [mitochondrial matrix]
Pyrimidine salvage (Bos taurus)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
MMAB adenosylates cob(I)alamin (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Bos taurus)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Bos taurus)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Bos taurus)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Bos taurus)
ATP [mitochondrial matrix]
Nicotinate metabolism (Bos taurus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Bos taurus)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Bos taurus)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Bos taurus)
CARKD dehydrates S-NAD(P)HX to NADPH (Bos taurus)
ATP [mitochondrial matrix]
Metabolism of proteins (Bos taurus)
Mitochondrial protein degradation (Bos taurus)
AFG3L2 degrades mitochondrial inner membrane proteins (Bos taurus)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Bos taurus)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Bos taurus)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Bos taurus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Bos taurus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Bos taurus)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Bos taurus)
ATP [mitochondrial matrix]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
PDK isozymes phosphorylate PDHC subunit E1 (Bos taurus)
ATP [mitochondrial matrix]
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
Mitochondrial ABC transporters (Bos taurus)
ABC7, mABC1 and mABC2 mediate heme transport (Bos taurus)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Bos taurus)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Bos taurus)
ATP [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
IDH3 complex decarboxylates isocitrate (Caenorhabditis elegans)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Caenorhabditis elegans)
OGDH dimer decarboxylates 2-OG (Caenorhabditis elegans)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Caenorhabditis elegans)
ATPase synthesizes ATP (Caenorhabditis elegans)
ATPase:ATP [mitochondrial inner membrane] (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Caenorhabditis elegans)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Pyruvate metabolism (Caenorhabditis elegans)
ME2 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Caenorhabditis elegans)
Regulation of pyruvate dehydrogenase (PDH) complex (Caenorhabditis elegans)
PDK isozymes phosphorylate PDHC subunit E1 (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Branched-chain amino acid catabolism (Caenorhabditis elegans)
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Caenorhabditis elegans)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Caenorhabditis elegans)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PC carboxylates PYR to OA (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Mitochondrial Fatty Acid Beta-Oxidation (Caenorhabditis elegans)
ACSF2 ligates CoA-SH to MCFA (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Caenorhabditis elegans)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Caenorhabditis elegans)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
MMAB adenosylates cob(I)alamin (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Caenorhabditis elegans)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Caenorhabditis elegans)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Nicotinate metabolism (Caenorhabditis elegans)
NADK2 dimer phosphorylates NAD+ to NADP+ (Caenorhabditis elegans)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Caenorhabditis elegans)
CARKD dehydrates S-NAD(P)HX to NADPH (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Metabolism of proteins (Caenorhabditis elegans)
Mitochondrial protein degradation (Caenorhabditis elegans)
AFG3L2 degrades mitochondrial inner membrane proteins (Caenorhabditis elegans)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Caenorhabditis elegans)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Caenorhabditis elegans)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Caenorhabditis elegans)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Caenorhabditis elegans)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Caenorhabditis elegans)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
PDK isozymes phosphorylate PDHC subunit E1 (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
Mitochondrial ABC transporters (Caenorhabditis elegans)
ABC7, mABC1 and mABC2 mediate heme transport (Caenorhabditis elegans)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Caenorhabditis elegans)
ATP [mitochondrial matrix]
Drug ADME (Canis familiaris)
Aspirin ADME (Canis familiaris)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
IDH3 complex decarboxylates isocitrate (Canis familiaris)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Canis familiaris)
OGDH dimer decarboxylates 2-OG (Canis familiaris)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Canis familiaris)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Canis familiaris)
ATPase synthesizes ATP (Canis familiaris)
ATPase:ATP [mitochondrial inner membrane] (Canis familiaris)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Canis familiaris)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Canis familiaris)
ATP [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
ME2 tetramer decarboxylates MAL to PYR (Canis familiaris)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Canis familiaris)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Canis familiaris)
Regulation of pyruvate dehydrogenase (PDH) complex (Canis familiaris)
PDK isozymes phosphorylate PDHC subunit E1 (Canis familiaris)
ATP [mitochondrial matrix]
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Ethanol oxidation (Canis familiaris)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Canis familiaris)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Canis familiaris)
Amino Acid conjugation (Canis familiaris)
Conjugation of carboxylic acids (Canis familiaris)
Conjugation of benzoate with glycine (Canis familiaris)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Canis familiaris)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Canis familiaris)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Canis familiaris)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Canis familiaris)
ACSM2B-like proteins transform ST to ST-CoA (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Canis familiaris)
Branched-chain amino acid catabolism (Canis familiaris)
BCKDK phosphorylates BCKDH (Canis familiaris)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Canis familiaris)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Canis familiaris)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Canis familiaris)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Canis familiaris)
ATP [mitochondrial matrix]
Urea cycle (Canis familiaris)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PC carboxylates PYR to OA (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Mitochondrial Fatty Acid Beta-Oxidation (Canis familiaris)
ACSF2 ligates CoA-SH to MCFA (Canis familiaris)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Canis familiaris)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Canis familiaris)
ATP [mitochondrial matrix]
Ketone body metabolism (Canis familiaris)
Synthesis of Ketone Bodies (Canis familiaris)
ACSS3 ligates CoA to CH3COO- (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Canis familiaris)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Canis familiaris)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)
ATP [mitochondrial matrix]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Canis familiaris)
ATP [mitochondrial matrix]
Pyrimidine salvage (Canis familiaris)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
MMAB adenosylates cob(I)alamin (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Canis familiaris)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Canis familiaris)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Canis familiaris)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Canis familiaris)
ATP [mitochondrial matrix]
Nicotinate metabolism (Canis familiaris)
NADK2 dimer phosphorylates NAD+ to NADP+ (Canis familiaris)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Canis familiaris)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Canis familiaris)
CARKD dehydrates S-NAD(P)HX to NADPH (Canis familiaris)
ATP [mitochondrial matrix]
Metabolism of proteins (Canis familiaris)
Mitochondrial protein degradation (Canis familiaris)
AFG3L2 degrades mitochondrial inner membrane proteins (Canis familiaris)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Canis familiaris)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Canis familiaris)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Canis familiaris)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Canis familiaris)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Canis familiaris)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Canis familiaris)
ATP [mitochondrial matrix]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
PDK isozymes phosphorylate PDHC subunit E1 (Canis familiaris)
ATP [mitochondrial matrix]
Transport of small molecules (Canis familiaris)
ABC-family proteins mediated transport (Canis familiaris)
Mitochondrial ABC transporters (Canis familiaris)
ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
ATP [mitochondrial matrix]
Drug ADME (Danio rerio)
Aspirin ADME (Danio rerio)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Danio rerio)
ATP [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
OGDH complex synthesizes succinyl-CoA from 2-OG (Danio rerio)
OGDH dimer decarboxylates 2-OG (Danio rerio)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Danio rerio)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Danio rerio)
ATPase synthesizes ATP (Danio rerio)
ATPase:ATP [mitochondrial inner membrane] (Danio rerio)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Danio rerio)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Danio rerio)
ATP [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
ME2 tetramer decarboxylates MAL to PYR (Danio rerio)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Danio rerio)
ATP [mitochondrial matrix]
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Amino Acid conjugation (Danio rerio)
Conjugation of carboxylic acids (Danio rerio)
Conjugation of benzoate with glycine (Danio rerio)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Danio rerio)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Danio rerio)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Danio rerio)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Danio rerio)
ACSM2B-like proteins transform ST to ST-CoA (Danio rerio)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PC carboxylates PYR to OA (Danio rerio)
ATP [mitochondrial matrix]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Mitochondrial Fatty Acid Beta-Oxidation (Danio rerio)
ACSF2 ligates CoA-SH to MCFA (Danio rerio)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Danio rerio)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Danio rerio)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Danio rerio)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Danio rerio)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Danio rerio)
ATP [mitochondrial matrix]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Danio rerio)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Metabolism of folate and pterines (Danio rerio)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Danio rerio)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Danio rerio)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Danio rerio)
ATP [mitochondrial matrix]
Nicotinate metabolism (Danio rerio)
Nicotinamide salvaging (Danio rerio)
CARKD dehydrates S-NAD(P)HX to NADPH (Danio rerio)
ATP [mitochondrial matrix]
Metabolism of proteins (Danio rerio)
Mitochondrial protein degradation (Danio rerio)
AFG3L2 degrades mitochondrial inner membrane proteins (Danio rerio)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Danio rerio)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Danio rerio)
ATP [mitochondrial matrix]
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
Mitochondrial ABC transporters (Danio rerio)
ABC7, mABC1 and mABC2 mediate heme transport (Danio rerio)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Danio rerio)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Danio rerio)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Danio rerio)
ATP [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
IDH3 complex decarboxylates isocitrate (Dictyostelium discoideum)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Dictyostelium discoideum)
OGDH dimer decarboxylates 2-OG (Dictyostelium discoideum)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Ethanol oxidation (Dictyostelium discoideum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Branched-chain amino acid catabolism (Dictyostelium discoideum)
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Dictyostelium discoideum)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
Synthesis of very long-chain fatty acyl-CoAs (Dictyostelium discoideum)
ACSF3 ligates CoA-SH to VLCFA (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Dictyostelium discoideum)
Propionyl-CoA catabolism (Dictyostelium discoideum)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Ketone body metabolism (Dictyostelium discoideum)
Synthesis of Ketone Bodies (Dictyostelium discoideum)
ACSS3 ligates CoA to CH3COO- (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Dictyostelium discoideum)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Dictyostelium discoideum)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
MMAB adenosylates cob(I)alamin (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Dictyostelium discoideum)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Dictyostelium discoideum)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Nicotinate metabolism (Dictyostelium discoideum)
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Dictyostelium discoideum)
CARKD dehydrates S-NAD(P)HX to NADPH (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism of proteins (Dictyostelium discoideum)
Mitochondrial protein degradation (Dictyostelium discoideum)
AFG3L2 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Dictyostelium discoideum)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Transport of small molecules (Dictyostelium discoideum)
ABC-family proteins mediated transport (Dictyostelium discoideum)
Mitochondrial ABC transporters (Dictyostelium discoideum)
ABC7, mABC1 and mABC2 mediate heme transport (Dictyostelium discoideum)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Dictyostelium discoideum)
ATP [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
IDH3 complex decarboxylates isocitrate (Drosophila melanogaster)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Drosophila melanogaster)
OGDH dimer decarboxylates 2-OG (Drosophila melanogaster)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Drosophila melanogaster)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Drosophila melanogaster)
ATPase synthesizes ATP (Drosophila melanogaster)
ATPase:ATP [mitochondrial inner membrane] (Drosophila melanogaster)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Drosophila melanogaster)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Drosophila melanogaster)
ATP [mitochondrial matrix]
Pyruvate metabolism (Drosophila melanogaster)
ME2 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Drosophila melanogaster)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Drosophila melanogaster)
Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Branched-chain amino acid catabolism (Drosophila melanogaster)
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Drosophila melanogaster)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Drosophila melanogaster)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Drosophila melanogaster)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PC carboxylates PYR to OA (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
Synthesis of very long-chain fatty acyl-CoAs (Drosophila melanogaster)
ACSF3 ligates CoA-SH to VLCFA (Drosophila melanogaster)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Drosophila melanogaster)
ACSF2 ligates CoA-SH to MCFA (Drosophila melanogaster)
ATP [mitochondrial matrix]
Ketone body metabolism (Drosophila melanogaster)
Synthesis of Ketone Bodies (Drosophila melanogaster)
ACSS3 ligates CoA to CH3COO- (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Drosophila melanogaster)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Drosophila melanogaster)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)
ATP [mitochondrial matrix]
Nucleotide salvage (Drosophila melanogaster)
Pyrimidine salvage (Drosophila melanogaster)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Metabolism of folate and pterines (Drosophila melanogaster)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Drosophila melanogaster)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Drosophila melanogaster)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Drosophila melanogaster)
ATP [mitochondrial matrix]
Nicotinate metabolism (Drosophila melanogaster)
NADK2 dimer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Drosophila melanogaster)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Drosophila melanogaster)
CARKD dehydrates S-NAD(P)HX to NADPH (Drosophila melanogaster)
ATP [mitochondrial matrix]
Metabolism of proteins (Drosophila melanogaster)
Mitochondrial protein degradation (Drosophila melanogaster)
AFG3L2 degrades mitochondrial inner membrane proteins (Drosophila melanogaster)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Drosophila melanogaster)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Drosophila melanogaster)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Drosophila melanogaster)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Drosophila melanogaster)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Drosophila melanogaster)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Drosophila melanogaster)
ATP [mitochondrial matrix]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
ATP [mitochondrial matrix]
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
Mitochondrial ABC transporters (Drosophila melanogaster)
ABC7, mABC1 and mABC2 mediate heme transport (Drosophila melanogaster)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Drosophila melanogaster)
ATP [mitochondrial matrix]
Drug ADME (Gallus gallus)
Aspirin ADME (Gallus gallus)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Gallus gallus)
ATP [mitochondrial matrix]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
ATP [mitochondrial matrix]
The tricarboxylic acid cycle (Gallus gallus)
succinate + CoASH + ATP <=> succinylCoA + ADP + Pi (Gallus gallus)
ATP [mitochondrial matrix]
succinylCoA + ADP + Pi <=> succinate + CoASH + ATP (Gallus gallus)
ATP [mitochondrial matrix]
Metabolism of proteins (Gallus gallus)
Mitochondrial protein degradation (Gallus gallus)
AFG3L2 degrades mitochondrial inner membrane proteins (Gallus gallus)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Gallus gallus)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Gallus gallus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Gallus gallus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Gallus gallus)
ATP [mitochondrial matrix]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
PDK isozymes phosphorylate PDHC subunit E1 (Gallus gallus)
ATP [mitochondrial matrix]
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
Mitochondrial ABC transporters (Gallus gallus)
ABC7, mABC1 and mABC2 mediate heme transport (Gallus gallus)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Gallus gallus)
ATP [mitochondrial matrix]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Defects in vitamin and cofactor metabolism (Homo sapiens)
Defects in cobalamin (B12) metabolism (Homo sapiens)
Defective MMAB causes MMA, cblB type (Homo sapiens)
Defective MMAB does not transfer adenosyl group from ATP to B12s (Homo sapiens)
ATP [mitochondrial matrix]
Diseases of branched-chain amino acid catabolism (Homo sapiens)
3-Methylcrotonyl-CoA carboxylase deficiency (Homo sapiens)
MCCC mutants don't synthesize beta-methylglutaconyl-CoA (Homo sapiens)
ATP [mitochondrial matrix]
Branched-chain ketoacid dehydrogenase kinase deficiency (Homo sapiens)
BCKDK loss-of-function mutations do not phosphorylate BCKDH (Homo sapiens)
ATP [mitochondrial matrix]
Drug ADME (Homo sapiens)
Aspirin ADME (Homo sapiens)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
IDH3 complex decarboxylates isocitrate (Homo sapiens)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Homo sapiens)
OGDH dimer decarboxylates 2-OG (Homo sapiens)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Homo sapiens)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Homo sapiens)
ATPase synthesizes ATP (Homo sapiens)
ATPase:ATP [mitochondrial inner membrane] (Homo sapiens)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Homo sapiens)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Homo sapiens)
ATP [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
ME2 tetramer decarboxylates MAL to PYR (Homo sapiens)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Homo sapiens)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Homo sapiens)
Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
PDK isozymes phosphorylate PDHC subunit E1 (Homo sapiens)
ATP [mitochondrial matrix]
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Ethanol oxidation (Homo sapiens)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Homo sapiens)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Homo sapiens)
Amino Acid conjugation (Homo sapiens)
Conjugation of carboxylic acids (Homo sapiens)
Conjugation of benzoate with glycine (Homo sapiens)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Homo sapiens)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Homo sapiens)
ACSM2B-like proteins transform ST to ST-CoA (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Homo sapiens)
Branched-chain amino acid catabolism (Homo sapiens)
BCKDK phosphorylates BCKDH (Homo sapiens)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Homo sapiens)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Homo sapiens)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Homo sapiens)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Homo sapiens)
ATP [mitochondrial matrix]
Threonine catabolism (Homo sapiens)
PXLP-GCAT dimer ligates CoASH to 2A-3OB to form Gly and Ac-CoA (Homo sapiens)
ATP [mitochondrial matrix]
Urea cycle (Homo sapiens)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PC carboxylates PYR to OA (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
ACSF3 ligates CoA-SH to VLCFA (Homo sapiens)
ATP [mitochondrial matrix]
SLC27A3 ligates CoA-SH to VLCFA (Homo sapiens)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Homo sapiens)
ACSF2 ligates CoA-SH to MCFA (Homo sapiens)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Homo sapiens)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Homo sapiens)
ATP [mitochondrial matrix]
mitochondrial fatty acid beta-oxidation of saturated fatty acids (Homo sapiens)
Beta oxidation of butanoyl-CoA to acetyl-CoA (Homo sapiens)
ACSM3,ACSM6 ligate CoA to BUT (Homo sapiens)
ATP [mitochondrial matrix]
Ketone body metabolism (Homo sapiens)
Synthesis of Ketone Bodies (Homo sapiens)
ACSS3 ligates CoA to CH3COO- (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Homo sapiens)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Homo sapiens)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)
ATP [mitochondrial matrix]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Homo sapiens)
ATP [mitochondrial matrix]
Pyrimidine salvage (Homo sapiens)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
MMAB adenosylates cob(I)alamin (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Homo sapiens)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Homo sapiens)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Homo sapiens)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Homo sapiens)
ATP [mitochondrial matrix]
Nicotinate metabolism (Homo sapiens)
NADK2 dimer phosphorylates NAD+ to NADP+ (Homo sapiens)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Homo sapiens)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Homo sapiens)
CARKD dehydrates S-NAD(P)HX to NADPH (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of RNA (Homo sapiens)
Mitochondrial RNA degradation (Homo sapiens)
SUPV3L1 unwinds double-stranded mitochondiral RNA (Homo sapiens)
ATP [mitochondrial matrix]
tRNA processing (Homo sapiens)
tRNA processing in the mitochondrion (Homo sapiens)
TRNT1 polymerizes CCA at the 3' end of pre-tRNA (Homo sapiens)
ATP [mitochondrial matrix]
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
AFG3L2 degrades mitochondrial inner membrane proteins (Homo sapiens)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Homo sapiens)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Homo sapiens)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Homo sapiens)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Homo sapiens)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Homo sapiens)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Homo sapiens)
ATP [mitochondrial matrix]
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Mitochondrial tRNA aminoacylation (Homo sapiens)
alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)
ATP [mitochondrial matrix]
Protein localization (Homo sapiens)
Mitochondrial protein import (Homo sapiens)
TIMM23 PAM translocates proteins from the mitochondrial intermembrane space to the mitochondrial matrix (Homo sapiens)
ATP [mitochondrial matrix]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
PDK isozymes phosphorylate PDHC subunit E1 (Homo sapiens)
ATP [mitochondrial matrix]
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
Mitochondrial ABC transporters (Homo sapiens)
ABC7, mABC1 and mABC2 mediate heme transport (Homo sapiens)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
ATP [mitochondrial matrix]
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Mus musculus)
ATP [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
IDH3 complex decarboxylates isocitrate (Mus musculus)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Mus musculus)
OGDH dimer decarboxylates 2-OG (Mus musculus)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Mus musculus)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Mus musculus)
ATPase synthesizes ATP (Mus musculus)
ATPase:ATP [mitochondrial inner membrane] (Mus musculus)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Mus musculus)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Mus musculus)
ATP [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
ME2 tetramer decarboxylates MAL to PYR (Mus musculus)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Mus musculus)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Mus musculus)
Regulation of pyruvate dehydrogenase (PDH) complex (Mus musculus)
PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)
ATP [mitochondrial matrix]
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Ethanol oxidation (Mus musculus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Mus musculus)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Mus musculus)
Amino Acid conjugation (Mus musculus)
Conjugation of carboxylic acids (Mus musculus)
Conjugation of benzoate with glycine (Mus musculus)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Mus musculus)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Mus musculus)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Mus musculus)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Mus musculus)
ACSM2B-like proteins transform ST to ST-CoA (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Mus musculus)
Branched-chain amino acid catabolism (Mus musculus)
BCKDK phosphorylates BCKDH (Mus musculus)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Mus musculus)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Mus musculus)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Mus musculus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Mus musculus)
ATP [mitochondrial matrix]
Urea cycle (Mus musculus)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PC carboxylates PYR to OA (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Fatty acyl-CoA biosynthesis (Mus musculus)
Synthesis of very long-chain fatty acyl-CoAs (Mus musculus)
ACSF3 ligates CoA-SH to VLCFA (Mus musculus)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Mus musculus)
ACSF2 ligates CoA-SH to MCFA (Mus musculus)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Mus musculus)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Mus musculus)
ATP [mitochondrial matrix]
Ketone body metabolism (Mus musculus)
Synthesis of Ketone Bodies (Mus musculus)
ACSS3 ligates CoA to CH3COO- (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Mus musculus)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Mus musculus)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Mus musculus)
ATP [mitochondrial matrix]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Mus musculus)
ATP [mitochondrial matrix]
Pyrimidine salvage (Mus musculus)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
MMAB adenosylates cob(I)alamin (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Mus musculus)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Mus musculus)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Mus musculus)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Mus musculus)
ATP [mitochondrial matrix]
Nicotinate metabolism (Mus musculus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Mus musculus)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Mus musculus)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Mus musculus)
CARKD dehydrates S-NAD(P)HX to NADPH (Mus musculus)
ATP [mitochondrial matrix]
Metabolism of proteins (Mus musculus)
Mitochondrial protein degradation (Mus musculus)
AFG3L2 degrades mitochondrial inner membrane proteins (Mus musculus)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Mus musculus)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Mus musculus)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Mus musculus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Mus musculus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Mus musculus)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Mus musculus)
ATP [mitochondrial matrix]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)
ATP [mitochondrial matrix]
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
Mitochondrial ABC transporters (Mus musculus)
ABC7, mABC1 and mABC2 mediate heme transport (Mus musculus)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Mus musculus)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Mus musculus)
ATP [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
OGDH complex synthesizes succinyl-CoA from 2-OG (Plasmodium falciparum)
OGDH dimer decarboxylates 2-OG (Plasmodium falciparum)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Plasmodium falciparum)
ATP [mitochondrial matrix]
Biological oxidations (Plasmodium falciparum)
Phase I - Functionalization of compounds (Plasmodium falciparum)
Ethanol oxidation (Plasmodium falciparum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Plasmodium falciparum)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Plasmodium falciparum)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Plasmodium falciparum)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of water-soluble vitamins and cofactors (Plasmodium falciparum)
Metabolism of folate and pterines (Plasmodium falciparum)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Plasmodium falciparum)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Plasmodium falciparum)
ATP [mitochondrial matrix]
Nicotinate metabolism (Plasmodium falciparum)
NADK2 dimer phosphorylates NAD+ to NADP+ (Plasmodium falciparum)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Plasmodium falciparum)
CARKD dehydrates S-NAD(P)HX to NADPH (Plasmodium falciparum)
ATP [mitochondrial matrix]
Metabolism of proteins (Plasmodium falciparum)
Mitochondrial protein degradation (Plasmodium falciparum)
AFG3L2 degrades mitochondrial matrix proteins (Plasmodium falciparum)
ATP [mitochondrial matrix]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Plasmodium falciparum)
ATP [mitochondrial matrix]
Drug ADME (Rattus norvegicus)
Aspirin ADME (Rattus norvegicus)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
IDH3 complex decarboxylates isocitrate (Rattus norvegicus)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Rattus norvegicus)
OGDH dimer decarboxylates 2-OG (Rattus norvegicus)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Rattus norvegicus)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Rattus norvegicus)
ATPase synthesizes ATP (Rattus norvegicus)
ATPase:ATP [mitochondrial inner membrane] (Rattus norvegicus)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Rattus norvegicus)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Rattus norvegicus)
ATP [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
ME2 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Rattus norvegicus)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate dehydrogenase (PDH) complex (Rattus norvegicus)
PDK isozymes phosphorylate PDHC subunit E1 (Rattus norvegicus)
ATP [mitochondrial matrix]
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Ethanol oxidation (Rattus norvegicus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Rattus norvegicus)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Rattus norvegicus)
Amino Acid conjugation (Rattus norvegicus)
Conjugation of carboxylic acids (Rattus norvegicus)
Conjugation of benzoate with glycine (Rattus norvegicus)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Rattus norvegicus)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Rattus norvegicus)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Rattus norvegicus)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Rattus norvegicus)
ACSM2B-like proteins transform ST to ST-CoA (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Branched-chain amino acid catabolism (Rattus norvegicus)
BCKDK phosphorylates BCKDH (Rattus norvegicus)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Rattus norvegicus)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Rattus norvegicus)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Rattus norvegicus)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Rattus norvegicus)
ATP [mitochondrial matrix]
Urea cycle (Rattus norvegicus)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PC carboxylates PYR to OA (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
Synthesis of very long-chain fatty acyl-CoAs (Rattus norvegicus)
ACSF3 ligates CoA-SH to VLCFA (Rattus norvegicus)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Rattus norvegicus)
ACSF2 ligates CoA-SH to MCFA (Rattus norvegicus)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Rattus norvegicus)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Rattus norvegicus)
ATP [mitochondrial matrix]
Ketone body metabolism (Rattus norvegicus)
Synthesis of Ketone Bodies (Rattus norvegicus)
ACSS3 ligates CoA to CH3COO- (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
AK4 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)
ATP [mitochondrial matrix]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Rattus norvegicus)
ATP [mitochondrial matrix]
Pyrimidine salvage (Rattus norvegicus)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
MMAB adenosylates cob(I)alamin (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Rattus norvegicus)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Rattus norvegicus)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Rattus norvegicus)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Rattus norvegicus)
ATP [mitochondrial matrix]
Nicotinate metabolism (Rattus norvegicus)
NADK2 dimer phosphorylates NAD+ to NADP+ (Rattus norvegicus)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Rattus norvegicus)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Rattus norvegicus)
CARKD dehydrates S-NAD(P)HX to NADPH (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism of proteins (Rattus norvegicus)
Mitochondrial protein degradation (Rattus norvegicus)
AFG3L2 degrades mitochondrial inner membrane proteins (Rattus norvegicus)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Rattus norvegicus)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Rattus norvegicus)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Rattus norvegicus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Rattus norvegicus)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Rattus norvegicus)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Rattus norvegicus)
ATP [mitochondrial matrix]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
PDK isozymes phosphorylate PDHC subunit E1 (Rattus norvegicus)
ATP [mitochondrial matrix]
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
Mitochondrial ABC transporters (Rattus norvegicus)
ABC7, mABC1 and mABC2 mediate heme transport (Rattus norvegicus)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
ATP [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
IDH3 complex decarboxylates isocitrate (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Saccharomyces cerevisiae)
OGDH dimer decarboxylates 2-OG (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Pyruvate metabolism (Saccharomyces cerevisiae)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Biological oxidations (Saccharomyces cerevisiae)
Phase I - Functionalization of compounds (Saccharomyces cerevisiae)
Ethanol oxidation (Saccharomyces cerevisiae)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Urea cycle (Saccharomyces cerevisiae)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of folate and pterines (Saccharomyces cerevisiae)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Nicotinate metabolism (Saccharomyces cerevisiae)
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Saccharomyces cerevisiae)
CARKD dehydrates S-NAD(P)HX to NADPH (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism of proteins (Saccharomyces cerevisiae)
Mitochondrial protein degradation (Saccharomyces cerevisiae)
AFG3L2 degrades mitochondrial inner membrane proteins (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Transport of small molecules (Saccharomyces cerevisiae)
ABC-family proteins mediated transport (Saccharomyces cerevisiae)
Mitochondrial ABC transporters (Saccharomyces cerevisiae)
ABC7, mABC1 and mABC2 mediate heme transport (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of vitamins, nucleosides, and related molecules (Saccharomyces cerevisiae)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Saccharomyces cerevisiae)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Saccharomyces cerevisiae)
ATP [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
IDH3 complex decarboxylates isocitrate (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Schizosaccharomyces pombe)
OGDH dimer decarboxylates 2-OG (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Pyruvate metabolism (Schizosaccharomyces pombe)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Schizosaccharomyces pombe)
Regulation of pyruvate dehydrogenase (PDH) complex (Schizosaccharomyces pombe)
PDK isozymes phosphorylate PDHC subunit E1 (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Biological oxidations (Schizosaccharomyces pombe)
Phase I - Functionalization of compounds (Schizosaccharomyces pombe)
Ethanol oxidation (Schizosaccharomyces pombe)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Urea cycle (Schizosaccharomyces pombe)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of folate and pterines (Schizosaccharomyces pombe)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Nicotinate metabolism (Schizosaccharomyces pombe)
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Schizosaccharomyces pombe)
CARKD dehydrates S-NAD(P)HX to NADPH (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Metabolism of proteins (Schizosaccharomyces pombe)
Mitochondrial protein degradation (Schizosaccharomyces pombe)
AFG3L2 degrades mitochondrial inner membrane proteins (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
Signaling by Retinoic Acid (Schizosaccharomyces pombe)
PDK isozymes phosphorylate PDHC subunit E1 (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Transport of small molecules (Schizosaccharomyces pombe)
ABC-family proteins mediated transport (Schizosaccharomyces pombe)
Mitochondrial ABC transporters (Schizosaccharomyces pombe)
ABC7, mABC1 and mABC2 mediate heme transport (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of vitamins, nucleosides, and related molecules (Schizosaccharomyces pombe)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Schizosaccharomyces pombe)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Schizosaccharomyces pombe)
ATP [mitochondrial matrix]
Drug ADME (Sus scrofa)
Aspirin ADME (Sus scrofa)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
IDH3 complex decarboxylates isocitrate (Sus scrofa)
ATP [mitochondrial matrix]
OGDH complex synthesizes succinyl-CoA from 2-OG (Sus scrofa)
OGDH dimer decarboxylates 2-OG (Sus scrofa)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Sus scrofa)
ATP [mitochondrial matrix]
Formation of ATP by chemiosmotic coupling (Sus scrofa)
ATPase synthesizes ATP (Sus scrofa)
ATPase:ATP [mitochondrial inner membrane] (Sus scrofa)
ATP [mitochondrial matrix]
Enzyme-bound ATP is released (Sus scrofa)
ATP [mitochondrial matrix]
ATPase:ATP [mitochondrial inner membrane] (Sus scrofa)
ATP [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
ME2 tetramer decarboxylates MAL to PYR (Sus scrofa)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Sus scrofa)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Sus scrofa)
Regulation of pyruvate dehydrogenase (PDH) complex (Sus scrofa)
PDK isozymes phosphorylate PDHC subunit E1 (Sus scrofa)
ATP [mitochondrial matrix]
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Ethanol oxidation (Sus scrofa)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Sus scrofa)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Sus scrofa)
Amino Acid conjugation (Sus scrofa)
Conjugation of carboxylic acids (Sus scrofa)
Conjugation of benzoate with glycine (Sus scrofa)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Sus scrofa)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Sus scrofa)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Sus scrofa)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Sus scrofa)
ACSM2B-like proteins transform ST to ST-CoA (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Sus scrofa)
Branched-chain amino acid catabolism (Sus scrofa)
BCKDK phosphorylates BCKDH (Sus scrofa)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Sus scrofa)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Sus scrofa)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Sus scrofa)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Sus scrofa)
ATP [mitochondrial matrix]
Urea cycle (Sus scrofa)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PC carboxylates PYR to OA (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Fatty acyl-CoA biosynthesis (Sus scrofa)
Synthesis of very long-chain fatty acyl-CoAs (Sus scrofa)
ACSF3 ligates CoA-SH to VLCFA (Sus scrofa)
ATP [mitochondrial matrix]
Mitochondrial Fatty Acid Beta-Oxidation (Sus scrofa)
ACSF2 ligates CoA-SH to MCFA (Sus scrofa)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Sus scrofa)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Sus scrofa)
ATP [mitochondrial matrix]
Ketone body metabolism (Sus scrofa)
Synthesis of Ketone Bodies (Sus scrofa)
ACSS3 ligates CoA to CH3COO- (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
(d)NDP + ATP <=> (d)NTP + ADP (NME4) (Sus scrofa)
ATP [mitochondrial matrix]
(d)NTP + ADP <=> (d)NDP + ATP (NME4) (Sus scrofa)
ATP [mitochondrial matrix]
AK4 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)
ATP [mitochondrial matrix]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Sus scrofa)
ATP [mitochondrial matrix]
Pyrimidine salvage (Sus scrofa)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Cobalamin (Cbl) metabolism (Sus scrofa)
MMAB adenosylates cob(I)alamin (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Sus scrofa)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Sus scrofa)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Sus scrofa)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Sus scrofa)
ATP [mitochondrial matrix]
Nicotinate metabolism (Sus scrofa)
NADK2 dimer phosphorylates NAD+ to NADP+ (Sus scrofa)
ATP [mitochondrial matrix]
NMNAT3 transfers an adenylyl group from ATP to NAMN to yield NAAD (Sus scrofa)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Sus scrofa)
CARKD dehydrates S-NAD(P)HX to NADPH (Sus scrofa)
ATP [mitochondrial matrix]
Metabolism of proteins (Sus scrofa)
Mitochondrial protein degradation (Sus scrofa)
AFG3L2 degrades mitochondrial inner membrane proteins (Sus scrofa)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Sus scrofa)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Sus scrofa)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Sus scrofa)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial inner membrane proteins (Sus scrofa)
ATP [mitochondrial matrix]
LONP1 degrades mitochondrial matrix proteins (Sus scrofa)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Sus scrofa)
ATP [mitochondrial matrix]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
PDK isozymes phosphorylate PDHC subunit E1 (Sus scrofa)
ATP [mitochondrial matrix]
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
Mitochondrial ABC transporters (Sus scrofa)
ABC7, mABC1 and mABC2 mediate heme transport (Sus scrofa)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
ATP [mitochondrial matrix]
Drug ADME (Xenopus tropicalis)
Aspirin ADME (Xenopus tropicalis)
ACSM2B-like proteins transform 2,5-DHBA to 2,5-DHB-CoA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
OGDH complex synthesizes succinyl-CoA from 2-OG (Xenopus tropicalis)
OGDH dimer decarboxylates 2-OG (Xenopus tropicalis)
ATP [mitochondrial matrix]
SUCLG1/A2 cleaves succinyl-CoA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Pyruvate metabolism (Xenopus tropicalis)
ME2 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
ATP [mitochondrial matrix]
PC carboxylates PYR to OA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Regulation of pyruvate metabolism (Xenopus tropicalis)
Regulation of pyruvate dehydrogenase (PDH) complex (Xenopus tropicalis)
PDK isozymes phosphorylate PDHC subunit E1 (Xenopus tropicalis)
ATP [mitochondrial matrix]
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Ethanol oxidation (Xenopus tropicalis)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [mitochondrial] (Xenopus tropicalis)
ATP [mitochondrial matrix]
Phase II - Conjugation of compounds (Xenopus tropicalis)
Amino Acid conjugation (Xenopus tropicalis)
Conjugation of carboxylic acids (Xenopus tropicalis)
Conjugation of benzoate with glycine (Xenopus tropicalis)
benzoate + Coenzyme A + ATP => benzoyl-CoA + AMP + pyrophosphate (Xenopus tropicalis)
ATP [mitochondrial matrix]
Conjugation of phenylacetate with glutamine (Xenopus tropicalis)
phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA + AMP + pyrophosphate (Xenopus tropicalis)
ATP [mitochondrial matrix]
Conjugation of salicylate with glycine (Xenopus tropicalis)
ACSM2B-like proteins transform ST to ST-CoA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Branched-chain amino acid catabolism (Xenopus tropicalis)
BCKDK phosphorylates BCKDH (Xenopus tropicalis)
ATP [mitochondrial matrix]
beta-methylcrotonyl-CoA + ATP + CO2 <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O [MCCA] (Xenopus tropicalis)
ATP [mitochondrial matrix]
beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + CO2 (MCCA) (Xenopus tropicalis)
ATP [mitochondrial matrix]
Glutamate and glutamine metabolism (Xenopus tropicalis)
glutamate + ATP + NADPH + H+ => L-glutamate gamma-semialdehyde + NADP+ + ADP + orthophosphate [P5CS] (Xenopus tropicalis)
ATP [mitochondrial matrix]
Urea cycle (Xenopus tropicalis)
2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial] (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
PC carboxylates PYR to OA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Mitochondrial Fatty Acid Beta-Oxidation (Xenopus tropicalis)
ACSF2 ligates CoA-SH to MCFA (Xenopus tropicalis)
ATP [mitochondrial matrix]
Propionyl-CoA catabolism (Xenopus tropicalis)
propionyl-CoA + CO2 + ATP <=> D-methylmalonyl-CoA + ADP + orthophosphate (Xenopus tropicalis)
ATP [mitochondrial matrix]
Ketone body metabolism (Xenopus tropicalis)
Synthesis of Ketone Bodies (Xenopus tropicalis)
ACSS3 ligates CoA to CH3COO- (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
AK4 phosphorylates (d)NMPs to (d)NDPs (Xenopus tropicalis)
ATP [mitochondrial matrix]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
dA, dG, or dI + ATP => dAMP, dGMP, or dIMP + ADP (DGUOK) (Xenopus tropicalis)
ATP [mitochondrial matrix]
Pyrimidine salvage (Xenopus tropicalis)
deoxycytidine, thymidine, or deoxyuridine + ATP => dCMP, TMP, or dUMP + ADP [TK2] (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Xenopus tropicalis)
Cobalamin (Cbl) metabolism (Xenopus tropicalis)
MMAB adenosylates cob(I)alamin (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of folate and pterines (Xenopus tropicalis)
MTHFD1L dimer ligates HCOOH to THF to form 10-formyl-THF (Xenopus tropicalis)
ATP [mitochondrial matrix]
MTHFD1L transforms 10-formyl-THF to HCOOH and THF (Xenopus tropicalis)
ATP [mitochondrial matrix]
Mitochondrial FPGS-1 transforms THF to THFPG (Xenopus tropicalis)
ATP [mitochondrial matrix]
Nicotinate metabolism (Xenopus tropicalis)
NADK2 dimer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)
ATP [mitochondrial matrix]
Nicotinamide salvaging (Xenopus tropicalis)
CARKD dehydrates S-NAD(P)HX to NADPH (Xenopus tropicalis)
ATP [mitochondrial matrix]
Metabolism of proteins (Xenopus tropicalis)
Mitochondrial protein degradation (Xenopus tropicalis)
AFG3L2 degrades mitochondrial inner membrane proteins (Xenopus tropicalis)
ATP [mitochondrial matrix]
AFG3L2 degrades mitochondrial matrix proteins (Xenopus tropicalis)
ATP [mitochondrial matrix]
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Xenopus tropicalis)
ATP [mitochondrial matrix]
CLPXP degrades mitochondrial matrix proteins (Xenopus tropicalis)
ATP [mitochondrial matrix]
PRKACA phosphorylates TFAM in the mitochondrial matrix (Xenopus tropicalis)
ATP [mitochondrial matrix]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
PDK isozymes phosphorylate PDHC subunit E1 (Xenopus tropicalis)
ATP [mitochondrial matrix]
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
Mitochondrial ABC transporters (Xenopus tropicalis)
ABC7, mABC1 and mABC2 mediate heme transport (Xenopus tropicalis)
ATP [mitochondrial matrix]
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Xenopus tropicalis)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
ATP [mitochondrial matrix]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
ATP [mitochondrial matrix]
External Reference Information
External Reference
ATP(4-) [ChEBI:30616]
Participates
as a component of
ATPase:ATP [mitochondrial inner membrane] (Caenorhabditis elegans)
ATPase:ATP [mitochondrial inner membrane] (Gallus gallus)
ATPase:ATP [mitochondrial inner membrane] (Bos taurus)
ATPase:ATP [mitochondrial inner membrane] (Sus scrofa)
ATPase:ATP [mitochondrial inner membrane] (Canis familiaris)
ATPase:ATP [mitochondrial inner membrane] (Drosophila melanogaster)
ATPase:ATP [mitochondrial inner membrane] (Danio rerio)
ATPase:ATP [mitochondrial inner membrane] (Mus musculus)
ATPase:ATP [mitochondrial inner membrane] (Homo sapiens)
ATPase:ATP [mitochondrial inner membrane] (Rattus norvegicus)
as an input of
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
succinate + CoASH + ATP <=> succinylCoA + ADP + Pi (Gallus gallus)
SUPV3L1 unwinds double-stranded mitochondiral RNA (Homo sapiens)
TRNT1 polymerizes CCA at the 3' end of pre-tRNA (Homo sapiens)
glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)
cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate (Homo sapiens)
methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)
isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)
glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)
glutamine + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate (Homo sapiens)
histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)
phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)
leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate (Homo sapiens)
threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate (Homo sapiens)
asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate (Homo sapiens)
arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)
proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate (Homo sapiens)
tyrosine + tRNA(Tyr) + ATP => Tyr-tRNA(Tyr) + AMP + pyrophosphate (Homo sapiens)
valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)
aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate (Homo sapiens)
AFG3L2 degrades mitochondrial inner membrane proteins (Saccharomyces cerevisiae)
AFG3L2 degrades mitochondrial inner membrane proteins (Schizosaccharomyces pombe)
AFG3L2 degrades mitochondrial inner membrane proteins (Dictyostelium discoideum)
AFG3L2 degrades mitochondrial inner membrane proteins (Caenorhabditis elegans)
AFG3L2 degrades mitochondrial inner membrane proteins (Drosophila melanogaster)