glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate

Stable Identifier
R-HSA-380216
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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EARS2 (mitochondrial glutamyl tRNA synthetase) catalyzes the reaction of glutamate, mitochondrial tRNA(Glu), and ATP to form Glu-tRNA(Glu), AMP, and pyrophosphate. The EARS2 gene has been identified by computational analysis of the human genome sequence; its function has been inferred from those of the biochemically characterized mitochondrial aspartyl and tyrosyl tRNA synthetases (Bonnefond et al. 2005).

Participants
Participates
Catalyst Activity

glutamate-tRNA ligase activity of EARS2 [mitochondrial matrix]

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