ACSS3 ligates CoA to CH3COO-

Stable Identifier
R-HSA-8875071
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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ACSS3 ligates CoA to CH3COO-
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Mitochondrial acyl-CoA synthetase short-chain family member 3 (ACSS3) belongs to the acyl-coenzyme A synthetase family that catalyse the "activation" of fatty acids by forming a thioester with coenzyme A (CoA-SH). ACSSs typically activate acetate, propionate, or butyrate. Ligation of acetate (CH3COO-) with CoA-SH is described here (Watkins et al. 2007).
Literature References
PubMed ID Title Journal Year
17762044 Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome

Pevsner, J, Jia, Z, Watkins, PA, Maiguel, D

J. Lipid Res. 2007
Participants
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Output
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as an event of
Catalyst Activity

acetate-CoA ligase activity of ACSS3 [mitochondrial matrix]

Physical Entity
ACSS3 [mitochondrial matrix] (Homo sapiens)
Activity
acetate-CoA ligase activity (GO:0003987)
Orthologous Events
ACSS3 ligates CoA to CH3COO- (Bos taurus)
ACSS3 ligates CoA to CH3COO- (Canis familiaris)
ACSS3 ligates CoA to CH3COO- (Dictyostelium discoideum)
ACSS3 ligates CoA to CH3COO- (Drosophila melanogaster)
ACSS3 ligates CoA to CH3COO- (Gallus gallus)
ACSS3 ligates CoA to CH3COO- (Mus musculus)
ACSS3 ligates CoA to CH3COO- (Rattus norvegicus)
ACSS3 ligates CoA to CH3COO- (Sus scrofa)
ACSS3 ligates CoA to CH3COO- (Xenopus tropicalis)
Cross References
Rhea
Authored
Jassal, B  (2016-06-01)
Reviewed
D'Eustachio, P  (2016-07-15)
Created
Jassal, B  (2016-06-01)
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