methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate

Stable Identifier
R-HSA-380157
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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MARS2 (mitochondrial methionyl tRNA synthetase) catalyzes the reaction of methionine, mitochondrial tRNA(Met), and ATP to form Met-tRNA(Met), AMP, and pyrophosphate. The enzyme, a class I tRNA synthetase, is a monomer (Spencer et al. 2004).

Literature References
PubMed ID Title Journal Year
15274629 Characterization of the human mitochondrial methionyl-tRNA synthetase

Spencer, AC, Heck, A, Takeuchi, N, Watanabe, K, Spremulli, LL

Biochemistry 2004
Participants
Participates
Catalyst Activity

methionine-tRNA ligase activity of MARS2 [mitochondrial matrix]

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Reviewed
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