succinylCoA + ADP + Pi <=> succinate + CoASH + ATP

Stable Identifier
R-GGA-372977
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
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succinylCoA + ADP + Pi <=> succinate + CoASH + ATP
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Mitochondrial succinyl-CoA synthetase catalyzes the reversible reaction of succinylCoA, ADP, and orthophosphate to form succinate, CoASH, and ATP. The enzyme is a heterodimer consisting of an alpha chain and a beta chain that determines whether the reaction involves adenine nucleotides (as here) or guanine nucleotides. The biochemical properties of the chicken enzyme have been studied in detail (Hamilton and Ottaway 1981) but the genes encoding its component proteins have not been cloned. The molecular properties of these proteins are inferred from those of their pigeon homologues (Johnson et al. 1998).

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Catalyst Activity

succinate-CoA ligase (ADP-forming) activity of succinyl-CoA synthetase dimer, ADP-forming [mitochondrial matrix]

Physical Entity
succinyl-CoA synthetase dimer, ADP-forming [mitochondrial matrix] (Gallus gallus)
Activity
succinate-CoA ligase (ADP-forming) activity (GO:0004775)
Authored
D'Eustachio, P  (2008-09-10)
Created
D'Eustachio, P  (2008-07-11)
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