histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate

Stable Identifier
R-HSA-380234
Type
Reaction [transition]
Species
Homo sapiens
Compartment
mitochondrial matrix
ReviewStatus
5/5
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histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
HARS2 (mitochondrial histidyl tRNA synthetase) catalyzes the reaction of histidine, mitochondrial tRNA(His), and ATP to form His-tRNA(His), AMP, and pyrophosphate. The enzyme is a class II tRNA synthetase (O'Hanlon et al. 1995).
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Catalyst Activity

histidine-tRNA ligase activity of HARS2 [mitochondrial matrix]

Physical Entity
HARS2 [mitochondrial matrix] (Homo sapiens)
Activity
histidine-tRNA ligase activity (GO:0004821)
Authored
D'Eustachio, P  (2008-11-29)
Reviewed
Antonellis, A  (2008-12-02)
Created
D'Eustachio, P  (2008-11-08)
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