SRC-1 [cytosol]

Stable Identifier
R-HSA-354153
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Proto-oncogene tyrosine-protein kinase SRC (EC 2.7.1.112) (p60-SRC) (C-SRC), Proto-oncogene tyrosine-protein kinase Src , p60-Src, c-Src, SRC1, SRC isoform 1
Icon
SRC-1 [cytosol] icon
SRC-1 [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P12931-1 SRC
Gene Names
SRC, SRC1
Other Identifiers
0002970286
0003290040
11723135_s_at
11723136_x_at
1558211_s_at
16913413
1938_at
1A07
1A08
1A09
1A1A
1A1B
1A1C
1A1E
1FMK
1HCS
1HCT
1KSW
1O41
1O42
1O43
1O44
1O45
1O46
1O47
1O48
1O49
1O4A
1O4B
1O4C
1O4D
1O4E
1O4F
1O4G
1O4H
1O4I
1O4J
1O4K
1O4L
1O4M
1O4N
1O4O
1O4P
1O4Q
1O4R
1SHD
1Y57
1YI6
1YOJ
1YOL
1YOM
213324_at
221284_s_at
2BDF
2BDJ
2H8H
2SRC
30875
3884193
3884196
3884198
3884199
3884200
3884202
3884203
3884207
3884209
3884210
3884214
3884215
3884216
3884221
3884223
3884227
3884228
3884229
38904_at
3VRO
3ZMP
3ZMQ
4023
4F59
4F5A
4F5B
4HXJ
4K11
4MXO
4MXX
4MXY
4MXZ
6714
8062377
A_14_P111562
A_23_P308603
AAA60584
AAH11566
AAH51270
AL133293
BC011566
BC051270
CAA26485
CAB004023
CCDS13294
CH471077
EAW76064
EAW76065
EAW76066
EAW76067
ENSG00000197122
ENSP00000350941
ENSP00000362659
ENSP00000362668
ENSP00000362680
ENST00000358208
ENST00000358208.8
ENST00000373558
ENST00000373558.2
ENST00000373567
ENST00000373567.6
ENST00000373578
ENST00000373578.6
EntrezGene:6714
EntrezGene:SRC
g4885608_3p_a_at
GE81507
GO:0000003
GO:0000166
GO:0000902
GO:0001545
GO:0002102
GO:0002223
GO:0002376
GO:0003013
GO:0003674
GO:0004672
GO:0004713
GO:0004715
GO:0005070
GO:0005080
GO:0005102
GO:0005158
GO:0005178
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005739
GO:0005743
GO:0005764
GO:0005768
GO:0005770
GO:0005773
GO:0005829
GO:0005856
GO:0005884
GO:0005886
GO:0005901
GO:0005975
GO:0006259
GO:0006464
GO:0006468
GO:0006629
GO:0006810
GO:0006914
GO:0006950
GO:0007010
GO:0007049
GO:0007155
GO:0007165
GO:0007169
GO:0007172
GO:0007173
GO:0007179
GO:0007186
GO:0007229
GO:0007267
GO:0007411
GO:0008022
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0009056
GO:0009058
GO:0009612
GO:0009615
GO:0010447
GO:0010628
GO:0010632
GO:0010634
GO:0010641
GO:0010907
GO:0010954
GO:0014068
GO:0014069
GO:0014911
GO:0016020
GO:0016032
GO:0016192
GO:0016236
GO:0016301
GO:0016310
GO:0016477
GO:0016740
GO:0018105
GO:0018108
GO:0019899
GO:0019900
GO:0019901
GO:0019904
GO:0020037
GO:0022407
GO:0022607
GO:0030154
GO:0030168
GO:0030331
GO:0030674
GO:0030900
GO:0031234
GO:0031295
GO:0031410
GO:0031625
GO:0031648
GO:0031667
GO:0031954
GO:0032148
GO:0032211
GO:0032463
GO:0032587
GO:0032869
GO:0032991
GO:0033146
GO:0033625
GO:0034330
GO:0034332
GO:0034446
GO:0034614
GO:0034641
GO:0035556
GO:0035635
GO:0036035
GO:0036120
GO:0038083
GO:0038096
GO:0038128
GO:0040007
GO:0040011
GO:0042169
GO:0042476
GO:0042493
GO:0042542
GO:0042592
GO:0043005
GO:0043065
GO:0043066
GO:0043114
GO:0043149
GO:0043154
GO:0043167
GO:0043226
GO:0043393
GO:0043406
GO:0043552
GO:0044281
GO:0044325
GO:0044403
GO:0044877
GO:0045056
GO:0045124
GO:0045296
GO:0045453
GO:0045737
GO:0045785
GO:0045892
GO:0045893
GO:0046628
GO:0046777
GO:0046875
GO:0048010
GO:0048011
GO:0048013
GO:0048471
GO:0048477
GO:0048856
GO:0048870
GO:0050715
GO:0050731
GO:0050839
GO:0050847
GO:0050877
GO:0050900
GO:0051057
GO:0051219
GO:0051222
GO:0051276
GO:0051385
GO:0051602
GO:0051604
GO:0051895
GO:0051897
GO:0051902
GO:0051974
GO:0060065
GO:0060444
GO:0060491
GO:0065003
GO:0070062
GO:0070301
GO:0070374
GO:0070542
GO:0070555
GO:0070851
GO:0071222
GO:0071253
GO:0071375
GO:0071393
GO:0071398
GO:0071456
GO:0071498
GO:0071560
GO:0071803
GO:0071902
GO:0086098
GO:0090263
GO:0097110
GO:0098609
GO:0098962
GO:0098978
GO:0099091
GO:1900182
GO:1902533
GO:1903997
GO:2000386
GO:2000394
GO:2000573
GO:2000588
GO:2000641
GO:2000811
GO:2001237
GO:2001243
GO:2001286
HGNC:11283
HPA030875
Hs.198298.0.S1_3p_at
Hs2.383588.1.A1_3p_s_at
ILMN_1685898
ILMN_1729987
IPR000719
IPR000980
IPR001245
IPR001452
IPR008266
IPR011009
IPR017441
IPR020635
IPR036028
IPR036860
K03212
K03213
K03214
K03215
K03216
K03217
K03218
K03218_at
LRG_1018
LRG_1018t1
M16237
M16243
M16244
M16245
MIM:114500
MIM:190090
MIM:616937
NM_005417
NM_198291
NP_005408
NP_938033
PF00017
PF00018
PF07714
PH_hs_0033377
PR00109
PR00401
PR00452
SM00219
SM00252
SM00326
SRC
SRC-201
SRC-202
SRC-203
SRC-204
TC20000273.hg
TC20001205.hg
UPI0000000CB3
UPI0000000D75
X02647
X03995
X03996
X03997
X03998
X03999
X04000
XM_011529013
XM_017028024
XM_017028025
XM_017028026
XM_017028027
XP_011527315
XP_016883513
XP_016883514
XP_016883515
XP_016883516
Participant Of
hasComponent
input
hasMember
Other forms of this molecule
Activated SRC-1 [cytosol]
p-Y419-SRC-1 [plasma membrane]
p-Y419-SRC [cytosol]
SRC-1 [plasma membrane]
Inferred To
SRC_RAT [cytosol] (Rattus norvegicus)
SRC-2 [cytosol] (Bos taurus)
SRC-2 [cytosol] (Caenorhabditis elegans)
SRC-2 [cytosol] (Canis familiaris)
SRC-2 [cytosol] (Danio rerio)
SRC-2 [cytosol] (Gallus gallus)
SRC-2 [cytosol] (Mus musculus)
SRC-2 [cytosol] (Sus scrofa)
SRC-2 [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
IntEnz
GeneCards
Orphanet
ZINC - Predictions - Purchasable
Interactors (53)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P18031 PTPN1  1 0.937 14
 UniProt:Q05397 PTK2  11 0.922 8
 UniProt:P03372 ESR1  8 0.864 12
 UniProt:P00533 EGFR  58 0.863 8
 UniProt:P22681 CBL  6 0.845 8
 UniProt:P27986 PIK3R1  15 0.822 7
 UniProt:P35968 KDR  2 0.77 6
 UniProt:P15941 MUC1  19 0.748 5
 UniProt:Q9H5V8 CDCP1      0.734 4
 UniProt:P04626 ERBB2  12 0.708 11
 UniProt:P08581 MET  7 0.702 4
 UniProt:P56945 BCAR1  4 0.688 3
 UniProt:Q01973 ROR1  2 0.682 9
 UniProt:Q9H204 MED28  1 0.656 3
 UniProt:Q13444 ADAM15  1 0.656 3
 UniProt:P18433 PTPRA  1 0.656 4
 UniProt:Q8WUM4 PDCD6IP  1 0.653 7
 UniProt:P55196 AFDN      0.65 7
 UniProt:Q14289 PTK2B  3 0.643 3
 UniProt:P49407 ARRB1  5 0.623 3
 UniProt:Q92569 PIK3R3  2 0.621 3
 UniProt:P07550 ADRB2  5 0.611 3
 UniProt:Q9ULH1 ASAP1  1 0.609 3
 UniProt:P35326 SPRR2A  2 0.602 3
 UniProt:Q62884 Q62884      0.602 3
 UniProt:P61978 HNRNPK  2 0.593 6
 UniProt:P27635 RPL10  1 0.591 6
 UniProt:Q68CZ2 TNS3  1 0.591 13
 UniProt:P16284 PECAM1  4 0.59 3
 UniProt:P00519 ABL1  5 0.589 2
 UniProt:Q07666 KHDRBS1  3 0.573 3
 UniProt:P34152 Ptk2  13 0.564 2
 UniProt:P07948 LYN  5 0.564 2
 UniProt:P32121 ARRB2  2 0.564 2
 myristoyl-CoA [ChEBI:15532]  3 0.558 2
 UniProt:Q8R5G7  1 0.558 3
 linoleoyl-CoA [ChEBI:15530]  2 0.558 2
 UniProt:Q9BR61 ACBD6  1 0.558 4
 UniProt:Q8TBB1 LNX1  1 0.556 6
 UniProt:P97288  1 0.544 2
 UniProt:P35222 CTNNB1  24 0.544 2
 UniProt:P25962  1 0.544 2
 UniProt:P40763 STAT3  10 0.527 5
 UniProt:P19367 HK1  4 0.524 2
 UniProt:Q13177 PAK2  11 0.524 2
 UniProt:P12814 ACTN1  3 0.524 2
 UniProt:Q9H3S7 PTPN23  1 0.499 2
 UniProt:Q9Y6K9 IKBKG  12 0.499 3
 ChEBI:39112 BOSUTINIB      0.499 2
 ChEBI:45783 IMATINIB      0.499 2
 UniProt:P12830 CDH1  10 0.499 2
 UniProt:O15455 TLR3  6 0.463 2
 UniProt:P23743 DGKA  1 0.462 2