p-S37,T41,S45, CTNNB1

Stable Identifier
R-HSA-8942369
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
p-S45-beta catenin
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P35222 CTNNB1
Gene Names
CTNNB1, CTNNB, OK/SW-cl.35, PRO2286
Chain
initiator methionine:1, chain:2-781
Reference Genes
BioGPS Gene:1499 CTNNB1
COSMIC (genes):CTNNB1 CTNNB1
CTD Gene:1499 CTNNB1
dbSNP Gene:1499 CTNNB1
ENSEMBL:ENSG00000168036 CTNNB1
HGNC:2514 CTNNB1
Monarch:1499 CTNNB1
NCBI Gene:1499 CTNNB1
OMIM:116806 CTNNB1
UCSC:P35222 CTNNB1
Reference Transcript
Other Identifiers
0001990132
108
11722167_s_at
11747387_a_at
11747388_x_at
11748951_a_at
11748952_x_at
11749021_s_at
11749022_x_at
11750680_x_at
1499
1554411_at
16939558
1950
1G3J
1JDH
1JPW
1LUJ
1P22
1QZ7
1T08
1TH1
201533_at
29159
29160
2G57
2GL7
2Z6H
3DIW
3FQN
3FQR
3SL9
3SLA
3TX7
40777_at
4DJS
8079021
A0A024R2Q3
A_14_P106050
A_14_P131897
A_23_P29495
A_23_P29499
A_33_P3421695
AAG35511
AAH58926
AAL89457
AAR18817
AB062292
AC104307
AF130085
AK289932
AY081165
AY463360
B4DGU4
BAB93475
BAF82621
BC058926
CAA61107
CAA79497
CAB000108
CAB001950
CCDS2694
CH471055
CTNNB1
CTNNB1-201
CTNNB1-202
CTNNB1-203
CTNNB1-204
EAW64625
EAW64626
EAW64627
EAW64628
ENSG00000168036
ENSP00000344456
ENSP00000379486
ENSP00000379488
ENSP00000385604
ENST00000349496
ENST00000396183
ENST00000396185
ENST00000405570
EntrezGene:1499
g4503130_3p_at
GE60116
GO:0000122
GO:0000578
GO:0000904
GO:0000922
GO:0000978
GO:0000979
GO:0001085
GO:0001102
GO:0001501
GO:0001569
GO:0001570
GO:0001658
GO:0001701
GO:0001702
GO:0001706
GO:0001708
GO:0001709
GO:0001711
GO:0001764
GO:0001822
GO:0001837
GO:0001840
GO:0001944
GO:0002052
GO:0002053
GO:0002089
GO:0003266
GO:0003338
GO:0003340
GO:0003677
GO:0003682
GO:0003690
GO:0003700
GO:0003713
GO:0004871
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005719
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005911
GO:0005912
GO:0005913
GO:0005916
GO:0005923
GO:0005925
GO:0005938
GO:0006351
GO:0006355
GO:0006357
GO:0007155
GO:0007160
GO:0007223
GO:0007268
GO:0007398
GO:0007399
GO:0007403
GO:0007507
GO:0008022
GO:0008134
GO:0008283
GO:0008284
GO:0008285
GO:0009948
GO:0009950
GO:0009953
GO:0009954
GO:0009987
GO:0010468
GO:0010628
GO:0010629
GO:0010718
GO:0010909
GO:0014704
GO:0016020
GO:0016055
GO:0016323
GO:0016328
GO:0016331
GO:0016337
GO:0016342
GO:0016525
GO:0016600
GO:0019827
GO:0019899
GO:0019900
GO:0019901
GO:0019903
GO:0021819
GO:0022009
GO:0022405
GO:0030018
GO:0030027
GO:0030054
GO:0030097
GO:0030154
GO:0030182
GO:0030217
GO:0030316
GO:0030324
GO:0030331
GO:0030521
GO:0030539
GO:0030856
GO:0030858
GO:0030877
GO:0030900
GO:0030901
GO:0030902
GO:0030997
GO:0031016
GO:0031069
GO:0031253
GO:0031528
GO:0031641
GO:0032212
GO:0032331
GO:0032355
GO:0032481
GO:0032993
GO:0033077
GO:0033234
GO:0034332
GO:0034333
GO:0034394
GO:0034613
GO:0034750
GO:0035050
GO:0035112
GO:0035115
GO:0035116
GO:0035257
GO:0035315
GO:0035411
GO:0035635
GO:0036023
GO:0042127
GO:0042129
GO:0042475
GO:0042493
GO:0042733
GO:0042981
GO:0043065
GO:0043123
GO:0043161
GO:0043234
GO:0043296
GO:0043410
GO:0043525
GO:0043588
GO:0044212
GO:0044325
GO:0044334
GO:0044336
GO:0044798
GO:0045177
GO:0045202
GO:0045294
GO:0045296
GO:0045453
GO:0045595
GO:0045596
GO:0045603
GO:0045667
GO:0045669
GO:0045670
GO:0045671
GO:0045743
GO:0045765
GO:0045892
GO:0045893
GO:0045944
GO:0045976
GO:0046332
GO:0046982
GO:0048096
GO:0048145
GO:0048469
GO:0048471
GO:0048489
GO:0048513
GO:0048538
GO:0048599
GO:0048617
GO:0048643
GO:0048660
GO:0048715
GO:0050681
GO:0050767
GO:0050808
GO:0051091
GO:0051145
GO:0051149
GO:0051571
GO:0051884
GO:0051973
GO:0060066
GO:0060070
GO:0060173
GO:0060439
GO:0060440
GO:0060441
GO:0060479
GO:0060484
GO:0060492
GO:0060548
GO:0060742
GO:0060769
GO:0060789
GO:0060916
GO:0061047
GO:0061154
GO:0061198
GO:0061324
GO:0061549
GO:0061550
GO:0070062
GO:0070369
GO:0070411
GO:0070491
GO:0070602
GO:0071363
GO:0071664
GO:0071681
GO:0071944
GO:0072001
GO:0072033
GO:0072053
GO:0072054
GO:0072079
GO:0072182
GO:0090279
GO:0097718
GO:1901215
GO:1903204
GO:1904501
GO:1904793
GO:1904796
GO:1904798
GO:1904837
GO:1904886
GO:1904888
GO:1904948
GO:1904954
GO:1990403
GO:1990791
GO:1990907
GO:1990909
GO:2000008
GO:2000017
GO:2000144
GO:2001234
HGNC:2514
HPA029159
HPA029160
Hs.476018
Hs2.171271.2.S1_3p_s_at
ILMN_1651617
ILMN_1746396
ILMN_1757350
IPR000225
IPR011989
IPR013284
IPR016024
MIM:114500
MIM:114550
MIM:116806
MIM:132600
MIM:155255
MIM:167000
MIM:615075
MIM:617572
NM_001098209
NM_001098210
NM_001904
NP_001091679
NP_001091680
NP_001317658
NP_001895
PF00514
PH_hs_0024820
PR01869
SM00185
uc003ckp.3
uc003ckq.3
uc003ckr.3
uc010hia.2
UPI000012862F
X87838
X87838_at
XM_005264886
XM_006712985
XM_017005738
XP_005264943
XP_006713048
XP_016861227
Z19054
Participant Of
hasComponent
Other forms of this molecule
CTNNB1 S45F [cytosol]
CTNNB1 S45P [cytosol]
pT41,S45-CTNNB1 S37F [cytosol]
pT41,S45-CTNNB1 S37A [cytosol]
pT41,S45-CTNNB1 S37C [cytosol]
pS37,T41,S45-CTNNB1 S33C [cytosol]
pS37,T41,S45-CTNNB1 S33F [cytosol]
pS37,T41,S45-CTNNB1 S33P [cytosol]
pS37,T41,S45-CTNNB1 S33Y [cytosol]
pS45-CTNNB1 T41A [cytosol]
pS45-CTNNB1 T41I [cytosol]
Ub-K,p-Y-CTNNB1 [cytosol]
p-Y-CTNNB1 [cytosol]
CTNNB1 [plasma membrane]
p-S552-CTNNB1 [nucleoplasm]
p-S552-CTNNB1 [cytosol]
CTNNB1(116-376) [cytosol]
CTNNB1(1-115) [cytosol]
p-S45 CTNNB1 [cytosol]
p-T41,S45 CTNNB1 [cytosol]
p-S33,S37,T41,S45 CTNNB1 [cytosol]
CTNNB1 [cytosol]
CTNNB1 [nucleoplasm]
Inferred To
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Bos taurus)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Canis familiaris)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Danio rerio)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Drosophila melanogaster)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Gallus gallus)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Mus musculus)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Rattus norvegicus)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Sus scrofa)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Taeniopygia guttata)
phospho-p-S37,T41,S45, CTNNB1 [cytosol] (Xenopus tropicalis)
Homologues of p-S37,T41,S45, CTNNB1 [cytosol] (Danio rerio)
Homologues of p-S37,T41,S45, CTNNB1 [cytosol] (Sus scrofa)
Modified Residues
Name
O-phospho-L-serine at 37
Coordinate
37
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 41
Coordinate
41
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 45
Coordinate
45
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
GeneCards
ZINC - Substances
DOCK Blaster
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
PDB
Interactors (84)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9NQB0 TCF7L2  4 0.967 25
 UniProt:P12830 CDH1  10 0.951 15
 UniProt:P25054 APC  13 0.949 17
 UniProt:P49841 GSK3B  4 0.94 16
 UniProt:O15169 AXIN1  11 0.94 44
 UniProt:P15884 TCF4  1 0.932 21
 UniProt:Q9Y297 BTRC  2 0.926 8
 UniProt:Q9NSA3 CTNNBIP1  1 0.917 12
 UniProt:P10275 AR  3 0.891 15
 UniProt:P19022 CDH2  3 0.887 8
 UniProt:P46937 YAP1  7 0.881 14
 UniProt:Q9UJU2 LEF1  2 0.858 9
 UniProt:P33151 CDH5  2 0.815 6
 UniProt:P36402 TCF7  1 0.779 4
 UniProt:P35221 CTNNA1  2 0.758 4
 UniProt:Q9UKB1 FBXW11  1 0.723 4
 UniProt:P63208 SKP1  2 0.713 3
 UniProt:Q5JTC6 AMER1  3 0.711 9
 UniProt:O43707 ACTN4  3 0.696 7
 UniProt:O35625 Axin1  3 0.688 4
 UniProt:Q96AC1 FERMT2  1 0.681 13
 UniProt:Q08050 FOXM1  3 0.672 16
 UniProt:P14923 JUP  5 0.669 3
 UniProt:P19838 NFKB1  8 0.667 3
 UniProt:Q01826 SATB1  5 0.66 9
 UniProt:P55197 AF10      0.656 5
 UniProt:Q13761 RUNX3  7 0.656 12
 UniProt:O00482-1 NR5A2  1 0.65 5
 UniProt:Q9GZV5 WWTR1  3 0.641 4
 UniProt:P26358 DNMT1  1 0.628 8
 UniProt:Q6P1J9 CDC73  1 0.616 9
 UniProt:Q9YGY0 AXIN1      0.609 2
 UniProt:P23470 PTPRG      0.609 2
 UniProt:Q12913 PTPRJ  2 0.609 2
 UniProt:P08575 PTPRC  2 0.609 2
 UniProt:Q9GZQ8 MAP1LC3B  3 0.602 5
 UniProt:P49789 FHIT      0.602 4
 UniProt:P18012 IPAC      0.602 4
 UniProt:P49023 PXN  4 0.602 4
 UniProt:P50402 EMD  1 0.591 3
 UniProt:Q8TEW0 PARD3  3 0.589 2
 UniProt:P11362 FGFR1  8 0.589 2
 UniProt:Q04206 RELA  5 0.589 3
 UniProt:Q13308 PTK7      0.581 5
 UniProt:Q9BZE0 GLIS2      0.581 6
 UniProt:Q13625 TP53BP2  1 0.576 5
 IntAct:EBI-4399559 UBIQ      0.576 3
 UniProt:O75564 JERKY      0.576 3
 UniProt:Q92793 CREBBP  1 0.573 2
 UniProt:P33724  5 0.571 5
 UniProt:P11388 TOP2A  3 0.57 5
 UniProt:Q9Y2T1 AXIN2  4 0.564 2
 UniProt:Q99697 PITX2  1 0.564 2
 UniProt:P16284 PECAM1  4 0.564 3
 UniProt:Q8TEK3 DOT1L  1 0.564 3
 UniProt:P12931 SRC  4 0.544 2
 UniProt:P00519 ABL1  5 0.544 2
 UniProt:Q03431 PTH1R  1 0.543 4
 UniProt:Q9NYF0 DACT1  1 0.537 3
 IntAct:EBI-5237192 AXIN2      0.527 2
 UniProt:P09803 Cdh1  1 0.527 3
 UniProt:Q9UKE5 TNIK  1 0.525 3
 UniProt:Q9EPK5 Wwtr1  4 0.525 2
 UniProt:P02511 CRYAB  1 0.524 3
 UniProt:A1Z199 A1Z199      0.524 2
 UniProt:P14618-1 PKM  1 0.524 3
 UniProt:Q9JHQ5  1 0.524 2
 UniProt:P14618 PKM  3 0.524 4
 UniProt:P29474 NOS3  7 0.524 4
 UniProt:O14746 TERT  1 0.524 2
 UniProt:Q15599 NHRF2      0.508 2
 UniProt:O00512 BCL9  1 0.508 2
 UniProt:P08069 IGF1R  3 0.499 3
 IntAct:EBI-6668710 TCF      0.499 3
 UniProt:Q9H6I2 SOX17  1 0.499 2
 UniProt:P18146 EGR1  1 0.499 7
 UniProt:Q92597 NDRG1  1 0.499 3
 UniProt:Q9Y265 RUVBL1  1 0.499 3
 UniProt:P49757 NUMB  1 0.499 2
 UniProt:O95071 UBR5      0.463 6
 UniProt:P46940 IQGAP1  3 0.463 3
 UniProt:Q14526 HIC1  2 0.463 2
 UniProt:Q14160 SCRIB  1 0.463 2
 UniProt:Q99593 TBX5  1 0.462 3