RHOD:GTP:DIAPH2-3 recruits SRC-1 to endosomes

Stable Identifier
R-HSA-5666104
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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RHOD:GTP:DIAPH2-3 complex recruits SRC to endosomes. SRC recruitment is necessary for RHOD:GTP:DIAPH2-3-mediated regulation of endosome-associated actin cytoskeleton and endosome motility (Gasman et al. 2003). SRC directly binds to DIAPH2 (Tominaga et al. 2000).

Literature References
PubMed ID Title Journal Year
12577064 RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

Gasman, S, Kalaidzidis, Y, Zerial, M

Nat. Cell Biol. 2003
10678165 Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling

Tominaga, T, Sahai, E, Chardin, P, McCormick, F, Courtneidge, SA, Alberts, AS

Mol. Cell 2000
Participants
Participant Of
Orthologous Events
Authored
Created