Reactome | TNFAIP1 [cytosol]

TNFAIP1 [cytosol]

Stable Identifier

R-HSA-9696531

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2, BACURD2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13829 TNFAIP1

Gene Names

TNFAIP1, BACURD2, EDP1

Chain

chain:1-316

Reference Genes

BioGPS Gene:7126 TNFAIP1

COSMIC (genes):TNFAIP1 TNFAIP1

CTD Gene:7126 TNFAIP1

dbSNP Gene:7126 TNFAIP1

ENSEMBL:ENSG00000109079 TNFAIP1

HGNC:11894 TNFAIP1

Monarch:7126 TNFAIP1

NCBI Gene:7126 TNFAIP1

OMIM:191161 TNFAIP1

UCSC:Q13829 TNFAIP1

Reference Transcript

RefSeq:NM_021137.4 TNFAIP1

Other Identifiers

11716011_a_at

11716012_at

11749224_a_at

16832438

201207_PM_at

201207_at

201208_PM_s_at

201208_s_at

36988_at

3715513

3715515

3715516

3715517

3715518

3715519

3715520

3715521

3715522

3715532

3715534

7126

8005847

A_14_P104931

A_23_P38446

GE79493

GO:0002376

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005737

GO:0005768

GO:0005829

GO:0006915

GO:0006955

GO:0007010

GO:0012501

GO:0016477

GO:0016567

GO:0016740

GO:0030163

GO:0030332

GO:0031267

GO:0031410

GO:0031463

GO:0035024

GO:0042802

GO:0043149

GO:0043161

GO:0043226

GO:0045740

GO:0048870

GO:0051260

GO:0065003

GO:0140096

HMNXSV003026761

ILMN_1655429

M80783_at

PH_hs_0031327

TC17000320.hg

g10863936_3p_at

g12804470_3p_a_at

Participates

as a member of

Inferred To

Tnfaip1 [cytosol] (Mus musculus)

Tnfaip1 [cytosol] (Rattus norvegicus)

tnfaip1 [cytosol] (Danio rerio)

tnfaip1 [cytosol] (Xenopus tropicalis)

TNFAIP1 [cytosol] (Bos taurus)

TNFAIP1 [cytosol] (Canis familiaris)

TNFAIP1 [cytosol] (Gallus gallus)

TNFAIP1 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENSP00000440749, ENSP00000226225, ENST00000544907, ENST00000226225

OpenTargets

ENSG00000109079

HPA

ENSG00000109079-TNFAIP1

PRO

Q13829

Pharos - Targets

Q13829

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O15160 POLR1C	2	POLR1C [cytosol] (R-HSA-1964454) POLR1C [nucleoplasm] (R-HSA-63498)	0.781	9
UniProt:Q9NQT4 EXOSC5	2	EXOSC5 [cytosol] (R-HSA-429889) EXOSC5 [nucleoplasm] (R-HSA-6791550)	0.718	6
UniProt:P25786 PSMA1	2	PSMA1 [cytosol] (R-HSA-68724) PSMA1 [nucleoplasm] (R-HSA-174333)	0.556	3
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.556	3
UniProt:P12931 SRC	6	MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408) MyrG,p-Y530-SRC [plasma membrane] (R-HSA-377598) MyrG-SRC [plasma membrane] (R-HSA-8876922) p-Y419-SRC [cytosol] (R-HSA-8964276) SRC [cytosol] (R-HSA-9628701) p-Y419-SRC [nucleoplasm] (R-HSA-8937690)	0.556	3
UniProt:P00441 SOD1	5	2xHC-SOD1 [cytosol] (R-HSA-3299726) SOD1 [cytosol] (R-HSA-350697) 2xHC-SOD1 [mitochondrial intermembrane space] (R-HSA-3777108) SOD1 [mitochondrial intermembrane space] (R-HSA-3777082) SOD1 [extracellular region] (R-HSA-350705)	0.556	3
UniProt:P02649 APOE	10	APOE [endoplasmic reticulum lumen] (R-HSA-6784908) p-APOE [endoplasmic reticulum lumen] (R-HSA-8956980) APOE [extracellular region] (R-HSA-174646) APOE [endocytic vesicle lumen] (R-HSA-3221641) APOE-4 [extracellular region] (R-HSA-9711070) APOE [plasma membrane] (R-HSA-174615) APOE [clathrin-coated endocytic vesicle membrane] (R-HSA-174651) APOE [endosome membrane] (R-HSA-174766) APOE [endosome lumen] (R-HSA-174804) APOE [early endosome] (R-HSA-2429687)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.556	3
UniProt:Q9UBU9 NXF1	2	NXF1 [nucleoplasm] (R-HSA-111690) NXF1 [cytosol] (R-HSA-156481)	0.556	3
UniProt:P01100 FOS	2	FOS [nucleoplasm] (R-HSA-450216) p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283)	0.556	3
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:O14786 NRP1	1	NRP1 [plasma membrane] (R-HSA-3008773)	0.527	2
UniProt:Q9UN19 DAPP1	2	p-Y139-DAPP1 [plasma membrane] (R-HSA-1112650) DAPP1 [cytosol] (R-HSA-197950)	0.488	2

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