Reactome | UniProt:P07900 HSP90AA1

UniProt:P07900 HSP90AA1

Type

Interactor (Protein)

Species

Homo sapiens

Synonyms

HS90A_HUMAN, A8K500, B3KPJ9, Q2PP14, Q5CAQ6, Q5CAQ7, Q9BVQ5

List of interactors in Reactome

Interactors (50)

Accession	#Entities	Reactome Entity	Confidence Score	Evidence (IntAct)
P53041	2	PPP5C [cytosol] (R-HSA-5675402) PPP5C [nucleoplasm] (R-HSA-5683410)	0.873	13
Q15185	2	PTGES3 [cytosol] (R-HSA-265269) PTGES3 [nucleoplasm] (R-HSA-5082403)	0.857	9
P04626	1	ERBB2 [plasma membrane] (R-HSA-372889)	0.856	6
P07900	1	HSP90AA1 [cytosol] (R-HSA-192864)	0.851	6
P31948	1	STIP1 [cytosol] (R-HSA-443857)	0.832	7
Q9UNE7	1	STUB1 [cytosol] (R-HSA-975970)	0.831	9
P06241	3	FYN [cytosol] (R-HSA-200917) p-Y420-FYN [cytosol] (R-HSA-391821) p-Y531-FYN [cytosol] (R-HSA-391819)	0.8	8
Q13451	1	FKBP5 [cytosol] (R-HSA-5618096)	0.8	9
P08238	1	HSP90AB1 [cytosol] (R-HSA-419617)	0.788	15
Q5S007	1	LRRK2 [cytosol] (R-HSA-5661173)	0.788	7
Q02790	2	FKBP4 [cytosol] (R-HSA-5618108) FKBP4 [nucleoplasm] (R-HSA-5324621)	0.784	9
P00533	2	EGFR [plasma membrane] (R-HSA-179837) EGFRvIII [plasma membrane] (R-HSA-1214162)	0.778	7
P04049	3	hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) RAF1 [cytosol] (R-HSA-167205)	0.744	15
P50750	1	CDK9 [nucleoplasm] (R-HSA-51801)	0.744	6
Q15831	2	STK11 [cytosol] (R-HSA-380954) STK11 [nucleoplasm] (R-HSA-164119)	0.744	6
Q99558	5	Active NIK [cytosol] (R-HSA-5607646) K48polyUb-NIK [cytosol] (R-HSA-5668525) MAP3K14 [cytosol] (R-HSA-168189) p-MAP3K14 [cytosol] (R-HSA-168187) p-T559-MAP3K14 [cytosol] (R-HSA-5668531)	0.744	5
P05412	4	JUN [cytosol] (R-HSA-168194) JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [cytosol] (R-HSA-8868682) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237)	0.678	4
O15111	2	CHUK [cytosol] (R-HSA-168104) p-T23-CHUK [cytosol] (R-HSA-198615)	0.669	4
P12931	5	MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408) MyrG-SRC [plasma membrane] (R-HSA-8876922) p-Y419-SRC [cytosol] (R-HSA-8964276) p-Y419-SRC [nucleoplasm] (R-HSA-8937690) SRC [cytosol] (R-HSA-9628701)	0.669	3
Q9Y6K9	3	IKBKG [cytosol] (R-HSA-168108) IKBKG [nucleoplasm] (R-HSA-4755413) monoSUMO1-K277,K309-IKBKG [nucleoplasm] (R-HSA-4755449)	0.669	4
P05067	12	APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-713) [extracellular region] (R-HSA-879340) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325)	0.666	5
P17612	2	PRKACA [cytosol] (R-HSA-57844) PRKACA [mitochondrial matrix] (R-HSA-9838291)	0.666	4
P11802	2	CDK4 [cytosol] (R-HSA-68330) CDK4 [nucleoplasm] (R-HSA-113843)	0.643	4
P61247	1	RPS3A [nucleoplasm] (R-HSA-6791182)	0.635	3
P43034	1	PAFAH1B1 [cytosol] (R-HSA-376249)	0.612	5
Q9Y239	1	NOD1 [cytosol] (R-HSA-168407)	0.589	2
Q13127	1	REST [nucleoplasm] (R-HSA-480506)	0.57	4
P10636	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521)	0.569	11
P06239	1	LCK [cytosol] (R-HSA-167609)	0.564	3
Q15750	5	TAB1 [cytosol] (R-HSA-167923) TAB1(1-132) [cytosol] (R-HSA-9729698) TAB1(1-444) [cytosol] (R-HSA-9729751) TAB1(133-504) [cytosol] (R-HSA-9729724) TAB1(445-504) [cytosol] (R-HSA-9729691)	0.564	2
Q9Y243	1	p-T305,S472-AKT3 [nucleoplasm] (R-HSA-3009365)	0.564	4
Q9UHH9	1	IP6K2 [nucleoplasm] (R-HSA-1015687)	0.558	2
P10599	4	2xHC-TXN [cytosol] (R-HSA-73668) 2xHC-TXN [nucleoplasm] (R-HSA-9617733) TXN [cytosol] (R-HSA-66000) TXN [nucleoplasm] (R-HSA-9617732)	0.556	3
P35222	6	CTNNB1 [cytosol] (R-HSA-448839) CTNNB1 [nucleoplasm] (R-HSA-3451168) CTNNB1(1-115) [cytosol] (R-HSA-202930) CTNNB1(116-376) [cytosol] (R-HSA-202950) p-S552-CTNNB1 [cytosol] (R-HSA-3134933) p-S552-CTNNB1 [nucleoplasm] (R-HSA-3134926)	0.556	3
O94966	1	USP19 [cytosol] (R-HSA-6781794)	0.527	7
P08631	1	HCK [cytosol] (R-HSA-167708)	0.527	3
P11142	5	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [plasma membrane] (R-HSA-936508) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2
P19388	1	POLR2E [nucleoplasm] (R-HSA-83713)	0.527	3
P31749	8	AKT1 [cytosol] (R-HSA-58252) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 [cytosol] (R-HSA-9841264) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.527	3
P36507	4	MAP2K2 [cytosol] (R-HSA-59504) MAP2K2(1-10) [cytosol] (R-HSA-5211334) MAP2K2(11-400) [cytosol] (R-HSA-5211337) p-S,T-MAP2K2 [cytosol] (R-HSA-109848)	0.527	3
P48729	2	CSNK1A1 [cilium] (R-HSA-5632507) CSNK1A1 [cytosol] (R-HSA-195263)	0.527	4
P51451	1	BLK [cytosol] (R-HSA-983580)	0.527	3
Q08881	1	ITK [cytosol] (R-HSA-202319)	0.527	2
Q13163	1	MAP2K5 [cytosol] (R-HSA-198722)	0.527	3
Q14004	1	CDK13 [nucleoplasm] (R-HSA-6797014)	0.527	3
Q15418	1	p-S221,T359,S363,S380,T573,S732-RPS6KA1 [nucleoplasm] (R-HSA-444292)	0.527	3
Q96GD4	1	AURKB [nucleoplasm] (R-HSA-4655360)	0.527	2
Q9H3Y6	1	SRMS [cytosol] (R-HSA-3902520)	0.527	3
P12830	3	CDH1(155-750) [plasma membrane] (R-HSA-202940) CDH1(155-882) [plasma membrane] (R-HSA-198003) CDH1(751-882) [plasma membrane] (R-HSA-202929)	0.499	2
P13569	5	CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) CFTR G551D [plasma membrane] (R-HSA-5678977) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	13

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