Reactome | KLF15 [nucleoplasm]

KLF15 [nucleoplasm]

Stable Identifier

R-HSA-8878735

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Krueppel-like factor 15, KLF15_HUMAN

Locations in the PathwayBrowser

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Literature References

PubMed ID	Title	Journal	Year
17438289	Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy Fisch, S, Gray, S, Heymans, S, Haldar, SM, Wang, B, Pfister, O, Cui, L, Kumar, A, Lin, Z, Sen-Banerjee, S, Das, H, Petersen, CA, Mende, U, Burleigh, BA, Zhu, Y, Pinto, YM, Pinto, Y, Liao, R, Jain, MK	Proc. Natl. Acad. Sci. U.S.A.	2007

External Reference Information

External Reference

UniProt:Q9UIH9 KLF15

Gene Names

KLF15, KKLF

Chain

chain:1-416

Reference Genes

BioGPS Gene:28999 KLF15

COSMIC (genes):KLF15 KLF15

CTD Gene:28999 KLF15

dbSNP Gene:28999 KLF15

ENSEMBL:ENSG00000163884 KLF15

HGNC:14536 KLF15

KEGG Gene (Homo sapiens):28999 KLF15

Monarch:28999 KLF15

NCBI Gene:28999 KLF15

OMIM:606465 KLF15

UCSC:Q9UIH9 KLF15

Reference Transcript

Other Identifiers

0005130397

11726210_at

16958638

221302_at

231015_at

2693512

2693513

2693521

2693522

2693523

2693530

2693531

28999

8090343

89228_at

A_23_P40805

A_24_P20327

GE557660

GO:0000785

GO:0000976

GO:0000977

GO:0000978

GO:0000981

GO:0001228

GO:0001678

GO:0003674

GO:0003677

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005694

GO:0006357

GO:0006464

GO:0006810

GO:0006950

GO:0007165

GO:0007267

GO:0008150

GO:0009058

GO:0010001

GO:0010468

GO:0014898

GO:0016607

GO:0030111

GO:0030154

GO:0032868

GO:0034641

GO:0042592

GO:0043167

GO:0043226

GO:0043231

GO:0045893

GO:0045944

GO:0046326

GO:0046872

GO:0048856

GO:0055085

GO:0072112

GO:1901653

GO:1990837

GO:2000757

HMNXSV003005182

Hs.157969.0.A1_3p_at

ILMN_1683133

PH_hs_0014031

TC03001736.hg

g7662493_3p_at

Participates

as an output of

Expression of KLF15 (Homo sapiens)

Cross References

RefSeq

XP_005247457.1, NP_054798.1

OpenTargets

ENSG00000163884

GeneCards

Q9UIH9

HPA

ENSG00000163884-KLF15

Ensembl

ENSP00000296233, ENST00000296233, ENSG00000163884

PRO

Q9UIH9

PDB

2ENT

Interactors (42)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43741 PRKAB2	3	PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [cytosol] (R-HSA-200411)	0.87	9
UniProt:O43167 ZBT24			0.83	10
UniProt:Q01658 DR1	1	DR1 [nucleoplasm] (R-HSA-3662280)	0.556	3
UniProt:Q9NX04 CA109			0.556	3
UniProt:Q00403 GTF2B	1	GTF2B [nucleoplasm] (R-HSA-65888)	0.556	3
UniProt:Q8WVZ9 KBTBD7	1	KBTBD7 [cytosol] (R-HSA-5658415)	0.556	3
UniProt:Q2TAC2-2 CCDC57			0.556	3
UniProt:Q9Y3C5 RNF11			0.556	3
UniProt:O60260-5 PRKN			0.556	3
UniProt:Q9Y5Q9 GTF3C3	1	GTF3C3 [nucleoplasm] (R-HSA-83691)	0.556	3
UniProt:P01100 FOS	2	p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283) FOS [nucleoplasm] (R-HSA-450216)	0.556	3
UniProt:D3DTS7 D3DTS7			0.556	3
UniProt:Q9Y3S2 ZN330			0.556	5
UniProt:O60333-2 KIF1B			0.556	3
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.556	3
UniProt:Q00613 HSF1	11	p-S303-HSF1 [cytosol] (R-HSA-4793927) p-S121-HSF1 [cytosol] (R-HSA-4793906) p-S307-HSF1 [cytosol] (R-HSA-4793929) p-S303,307-HSF1 [cytosol] (R-HSA-4793922) HSF1 [nucleoplasm] (R-HSA-5082385) hC36,103-HSF1 [cytosol] (R-HSA-4793916) p-S230-hC36,103-HSF1 [nucleoplasm] (R-HSA-5082361) p-S326-hC36,103-HSF1 [nucleoplasm] (R-HSA-5082355) Ac-K80-hC36,103-HSF1 [nucleoplasm] (R-HSA-5097238) HSF1 [cytosol] (R-HSA-3371452) hC36,103-HSF1 [nucleoplasm] (R-HSA-3371416)	0.556	3
UniProt:P31153 MAT2A	1	MAT2A [cytosol] (R-HSA-174363)	0.556	3
UniProt:P04792 HSPB1	3	p-S15,S78,S82-HSP27 [cytosol] (R-HSA-5218697) HSPB1 [cytosol] (R-HSA-450563) p-S78,S82 HSPB1 [cytosol] (R-HSA-5687009)	0.556	3
UniProt:P62491 RAB11A	4	GGC-RAB11A [cytosol] (R-HSA-8873781) RAB11A [recycling endosome membrane] (R-HSA-2029023) RAB11A [cytosol] (R-HSA-5623395) GGC-RAB11A [cytoplasmic vesicle membrane] (R-HSA-1458519)	0.556	3
UniProt:Q13952-2 NFYC			0.556	3
UniProt:P52597 HNRNPF	2	HNRNPF [plasma membrane] (R-HSA-8950714) HNRNPF [nucleoplasm] (R-HSA-71937)	0.556	3
UniProt:O76024 WFS1	3	p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:P37840 SNCA	4	SNCA [extracellular region] (R-HSA-976954) SNCA A30P [cytosol] (R-HSA-5658569) SNCA [cytosol] (R-HSA-5658500) Ub-SNCA [cytosol] (R-HSA-5660754)	0.556	3
UniProt:Q13148 TADBP			0.556	6
UniProt:Q16656-4 NRF1			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q9BWG6 SCNM1			0.556	3
UniProt:Q92997 DVL3	4	p-DVL3 [cytosol] (R-HSA-201680) pp-DVL3 [cytosol] (R-HSA-3772400) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	5
UniProt:O14901 KLF11			0.556	3
UniProt:Q9H3H3-3 C11ORF68			0.556	3
UniProt:Q8N2W9 PIAS4	2	SUMO1-K35-PIAS4 [nucleoplasm] (R-HSA-3968415) PIAS4 [nucleoplasm] (R-HSA-2993789)	0.556	3
UniProt:O14645 IDLC			0.556	3
UniProt:Q9NUL5-4 SHFL			0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:Q96A83-2 Q96A832			0.556	3
UniProt:P28799 GRN	2	GRN [extracellular region] (R-HSA-6806217) GRN [azurophil granule lumen] (R-HSA-6799168)	0.556	3
UniProt:P36508 ZNF76			0.556	3
UniProt:P42261 GRIA1	6	GRIA1 [ER to Golgi transport vesicle membrane] (R-HSA-5689810) GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689811) GRIA1 [endoplasmic reticulum membrane] (R-HSA-5689460) GRIA1 [endocytic vesicle membrane] (R-HSA-3004479) GRIA1 [plasma membrane] (R-HSA-3004495) p-S849-GRIA1 [plasma membrane] (R-HSA-9620488)	0.556	3
UniProt:P12931 SRC	6	p-Y416-SRC [cytosol] (R-HSA-8964276) SRC [cytosol] (R-HSA-9628701) p-Y419-SRC [nucleoplasm] (R-HSA-8937690) MyrG-SRC [plasma membrane] (R-HSA-8876922) MyrG,p-Y530-SRC [plasma membrane] (R-HSA-377598) MyrG-p-Y419-SRC [plasma membrane] (R-HSA-1810408)	0.556	3
UniProt:O15160 POLR1C	2	POLR1C [nucleoplasm] (R-HSA-63498) POLR1C [cytosol] (R-HSA-1964454)	0.556	3
UniProt:Q8N9N5-2 BANP			0.556	3
UniProt:Q9UKG1 APPL1	1	APPL1 [endosome membrane] (R-HSA-373630)	0.488	2

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