Reactome | Escherichia coli

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Escherichia coli Show undefined attributes

abbreviation	ECO
created	[InstanceEdit:159871] D'Eustachio, P, 2005-03-17 16:57:56
crossReference	[DatabaseIdentifier:159877] NCBI_taxonomy:562
dbId	159879
displayName	Escherichia coli
modified	[InstanceEdit:9759771] Stephan, Ralf, 2021-12-11
name	Escherichia coli
schemaClass	Species
superTaxon	[Taxon:159874] Escherichia
taxId	562

Referrals

(superTaxon)

[Species:9760713] Escherichia coli O78:H11
[Species:9638642] Escherichia coli O6:K15:H31
[Species:9926952] Escherichia coli O127:H6
[Species:9638490] Escherichia coli O157:H7

(relatedSpecies)

[Pathway:R-HSA-5602680] MyD88 deficiency (TLR5)
[FailedReaction:R-HSA-5602316] Defective MyD88 does not oligomerize within the complex of activated TLR5
[Complex:R-HSA-9037690] MyD88 variant:TLR5:bacterial flagellin [plasma membrane]
[Pathway:R-HSA-5603037] IRAK4 deficiency (TLR5)
[FailedReaction:R-HSA-5602603] IRAK4 deficiency blocks formation of the MyD88-IRAK4 Myddosome in the TLR5 pathway
[Reaction:R-HSA-8936356] GUCY2C trimer binds sta1
[Complex:R-HSA-8936363] GUCY2C trimer:sta1 [plasma membrane]
[Pathway:R-HSA-9640148] Infection with Enterobacteria
[Pathway:R-HSA-9760173] Secretion of toxins
[BlackBoxEvent:R-HSA-9926154] HlyE-loaded OMV leaves cell
[Reaction:R-HSA-9926021] HlyB:HlyD:TolC transports HlyA from periplasm to extracellular space
[Reaction:R-HSA-9926041] HlyB:HlyD:TolC transports HlyA from cytosol to periplasm
[Reaction:R-HSA-9760573] TolC complex exports STa
[Reaction:R-HSA-9760559] DsbA catalyzes disulfide crosslink formation on STa
[Reaction:R-HSA-9760521] Unknown peptidase cleaves pro-STa
[Reaction:R-HSA-9760663] EltA binds EltB
[Reaction:R-HSA-9912368] LepB cleaves pre-EltA
[Reaction:R-HSA-9912371] LepB cleaves pre-EltB
[Reaction:R-HSA-9911383] LepB cleaves prepro-STa
[Reaction:R-HSA-9760310] SecA:SecYEG transports proteins from cytosol to periplasmic space
[Pathway:R-HSA-9931953] Biofilm formation
[BlackBoxEvent:R-HSA-9932121] Unknown transporter exports CA to extracellular space
[Reaction:R-HSA-9932466] Bcs complex exports pEtN-cellulose
[BlackBoxEvent:R-HSA-9932322] BcsG transfers pEtN from PE onto cellulose
[BlackBoxEvent:R-HSA-9932210] Bcs complex synthesizes cellulose from UDP-Glc
[Pathway:R-HSA-9638630] Attachment of bacteria to epithelial cells
[Reaction:R-HSA-9638636] PapG binds diGal
[Reaction:R-HSA-9638589] SfaS binds the laminin matrix
[Complex:R-HSA-9638618] SfaS:Laminin network [extracellular region]
[Reaction:R-HSA-9638552] SfaS binds the fibronectin matrix
[Complex:R-HSA-9638576] Sfas:Fibronectin matrix [extracellular region]
[Reaction:R-HSA-9638571] FimH binds D-mannose moiety on host cell
[Complex:R-HSA-9932000] FimH:D-mannose bearing glycoproteins [plasma membrane]
[Reaction:R-HSA-9638628] DraE binds Collagen IV
[Complex:R-HSA-9638651] DraE:Collagen IV [extracellular region]
[Reaction:R-HSA-9932034] CsgA binds the fibronectin matrix
[Complex:R-HSA-9932035] CsgA:fibronectin matrix [extracellular region]
[Pathway:R-HSA-9638737] Action of antimicrobials and antimicrobial resistance
[Pathway:R-HSA-9913143] Antimicrobial resistance
[Reaction:R-HSA-9931565] EmrE dimer exports xenobiotics to periplasm
[Reaction:R-HSA-9911520] TEM-1 hydrolyzes penicillin G
[Reaction:R-HSA-9914083] MdtE:MdtF:TolC exports beta-lactams to extracellular space
[Reaction:R-HSA-9931163] Gdx dimer exports cationic aromatics to periplasm
[Reaction:R-HSA-9911516] AcrA:AcrB:TolC transports antibiotics from the periplasm to the extracellular region
[Reaction:R-HSA-9913128] TetA exports tetracyclines
[Reaction:R-HSA-9913672] OqxA exports fluoroquinolones
[Reaction:R-HSA-9911512] AcrA:AcrB:TolC transports antibiotics from the cytosol to the periplasm
[Reaction:R-HSA-9914089] MdtE:MdtF:TolC exports beta-lactams to the periplasm
[Reaction:R-HSA-9913437] Pef exports fluoroquinolones
[Reaction:R-HSA-9913373] AAC(6?)-Ib acetylates ciprofloxacin
[Reaction:R-HSA-9911517] MdfA transports tetracyclines from the cytosol to the periplasmic space
[Reaction:R-HSA-9913106] TetB exports tetracyclines
[Reaction:R-HSA-9911510] MacA:MacB:TolC transports azithromycin from the periplasm to the extracellular region
[Reaction:R-HSA-9911514] MacA:MacB:TolC transports azithromycin from the cytosol to the periplasm
[Reaction:R-HSA-9911511] Qnr binds gyrase
[Pathway:R-HSA-9638771] Action of antimicrobials
[Reaction:R-HSA-9912784] Tetracycline antibiotics bind to 16S rRNA
[Reaction:R-HSA-9911461] ?-lactam antibiotics bind MrcB
[Reaction:R-HSA-9913142] Fluoroquinolones bind gyrase
[Polymerisation:R-HSA-9911463] MrcB elongates peptidoglycan
[Pathway:R-HSA-9638482] Metal ion assimilation from the host
[Reaction:R-HSA-9931048] FecBCDE imports Fe3+-citrates to cytosol
[Reaction:R-HSA-9911596] FeoAB transports Fe2+ from periplasmic space to the cytosol
[Pathway:R-HSA-9927020] Heme assimilation
[Reaction:R-HSA-9927930] DppBCDF transports heme to cytosol
[Reaction:R-HSA-9927609] PBP binds heme
[Reaction:R-HSA-9927224] ChuA imports heme to periplasm
[BlackBoxEvent:R-HSA-9926936] EspC(54-1018) cleaves hemoglobin
[BlackBoxEvent:R-HSA-9927009] Hbp(53-1100) cleaves hemoglobin
[Reaction:R-HSA-9926963] Hbp cis-autocleaves
[Reaction:R-HSA-9926981] Bam complex inserts Hbp into outer membrane
[Reaction:R-HSA-9928256] YbtPQ transports Ybt:Fe/Cu to the cytosol
[Reaction:R-HSA-9931043] FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm
[Reaction:R-HSA-9928035] ZnuABC transports Zn2+ to cytosol
[Pathway:R-HSA-9638334] Iron assimilation using enterobactin
[Reaction:R-HSA-9911599] Fes hydrolyses ferrienterobactin to DHBS
[Reaction:R-HSA-9911603] FepC:FepD:FepG transports ferrienterobactin from the periplasmic space to the cytosol
[Reaction:R-HSA-9911597] Ferrienterobactin binds to FepB
[Reaction:R-HSA-9911602] FepA:TonB:ExbB:ExbD transports ferrienterobactin from the extracellular region to the periplasmic space
[Reaction:R-HSA-9911601] Enterobactin binds Fe3+
[Reaction:R-HSA-9911600] Efflux pump complexes transport enterobactin from periplasmic space to extracellular region
[Reaction:R-HSA-9911595] EntS transports enterobactin from cytosol to periplasmic space
[Reaction:R-HSA-9927945] YqjH reduces FeEnt
[Reaction:R-HSA-9930911] FhuBCD imports FeAer to the cytosol
[Reaction:R-HSA-9911605] FyuA transports Ybt:Fe/Cu from extracellular space to the periplasm
[Reaction:R-HSA-9911594] Ybt binds Fe3+
[Reaction:R-HSA-9928204] Ybt binds Cu2+
[Reaction:R-HSA-9930902] IutA imports FeAer to the periplasm
[Reaction:R-HSA-9930941] Aerobactin binds Fe3+
[Complex:R-HSA-188027] TLR5 homodimer:bacterial flagellin [plasma membrane]
[DefinedSet:R-HSA-975862] Activated TLR5 or TLR10 homodimer [plasma membrane]
[Complex:R-HSA-975864] oligo-MyD88:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975870] p-S,2T-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975881] hp-IRAK1 or p-IRAK2 : pIRAK4:MyD88:activated TLR5/10 [plasma membrane]
[Complex:R-HSA-975869] TRAF6:hp-IRAK1/or p-IRAK2:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975883] pp-IRAK1:p-IRAK4:oligo-MyD88 :activated TLR5 or 10 complex [plasma membrane]
[Complex:R-HSA-975877] hp-IRAK1:activated IRAK4:MyD88oligomer:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975872] p-IRAK1:p-IRAK4:oligo-MyD88l:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975868] IRAK1:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane]
[Complex:R-HSA-975875] IRAK1 or IRAK2 :p-IRAK4:MyD88 oligomer:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975876] IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
[Complex:R-HSA-975860] MyD88 complexed with the activated TLR5 or 10 receptor [plasma membrane]
[Reaction:R-HSA-188025] Flagellin binds to TLR5
[Reaction:R-HSA-975866] MyD88 forms a complex with the activated TLR receptor
[Reaction:R-HSA-975880] MyD88 oligomerization within the complex of activated TLR:MyD88
[Reaction:R-HSA-975873] IRAK4 binds to MyD88 bound to the activated TLR5 or 10 receptor
[Reaction:R-HSA-975865] IRAK4 autophosphorylation within the complex activated TLR:MyD88
[Reaction:R-HSA-975852] IRAK1/or IRAK2 binds to the activated IRAK4 :oligo MyD88:activated TLR5 or 10 complex
[Reaction:R-HSA-975878] First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR
[Reaction:R-HSA-975874] Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex
[Reaction:R-HSA-975853] Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR
[Complex:R-HSA-975859] IRAK2:p-S,2T-IRAK4:oligo-MyD88:activated TLR5/10 [plasma membrane]
[Complex:R-HSA-975867] p-IRAK2:p-IRAK4:oligo-MyD88:activated TLR5 or 10 [plasma membrane]
[Reaction:R-HSA-975861] Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex
[Reaction:R-HSA-975857] TRAF6 binds to hp- IRAK1 or p-IRAK2
[Reaction:R-HSA-975879] Dissociation of hp-IRAK1:TRAF6 or IRAK2:TRAF6-oligomer from the activated TLR5 or 10:oligo-Myd88:p-IRAK4 complex
[Pathway:R-HSA-975871] MyD88 cascade initiated on plasma membrane
[Pathway:R-HSA-168176] Toll Like Receptor 5 (TLR5) Cascade
[Pathway:R-HSA-168142] Toll Like Receptor 10 (TLR10) Cascade
[Reaction:R-HSA-6789160] Hydrogen peroxide and Fe2+ react to hydroxyl, hydroxide and Fe3+
[Pathway:R-HSA-168898] Toll-like Receptor Cascades

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