Reactome | Unknown peptidase cleaves pro-STa

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Unknown peptidase cleaves pro-STa Show undefined attributes

authored	[InstanceEdit:9760325] Stephan, Ralf, 2021-12-16
catalystActivity	[CatalystActivity:9760518] endopeptidase activity of Unknown peptidase [periplasmic space]
category	transition
compartment	[Compartment:1222638] periplasmic space
created	[InstanceEdit:9760533] Stephan, Ralf, 2021-12-19
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9760521
disease	[Disease:3134792] bacterial infectious disease
displayName	Unknown peptidase cleaves pro-STa
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9760173] Secretion of toxins - Homo sapiens
followingEvent	[Reaction:R-HSA-9760559] DsbA catalyzes disulfide crosslink formation on STa - Homo sapiens
input	[DefinedSet:R-ECO-9760329] pro-STa [periplasmic space]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9760529] Extracellular secretion of Escherichia coli heat-stable enterotoxin I across the outer membrane [LiteratureReference:9760530] Two precursors of the heat-stable enterotoxin of Escherichia coli: evidence of extracellular processing [LiteratureReference:9760531] Secretion of the STA3 heat-stable enterotoxin of Escherichia coli: extracellular delivery of Pro-STA is accomplished by either Pro or STA
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	Unknown peptidase cleaves pro-STa
output	[DefinedSet:R-ECO-9760528] STa-SH [periplasmic space]
precedingEvent	[Reaction:R-HSA-9911383] LepB cleaves prepro-STa - Homo sapiens
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9760521
summation	[Summation:9760524] The E.coli heat-stable enterotoxin I propeptide (pro-STa) ge...

Referrals

(hasEvent)	[Pathway:R-HSA-9760173] Secretion of toxins
(precedingEvent)	[Reaction:R-HSA-9760559] DsbA catalyzes disulfide crosslink formation on STa

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