Reactome | FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm

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FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm Show undefined attributes

authored	[InstanceEdit:9931008] Stephan, Ralf, 2024-12-08
catalystActivity	[CatalystActivity:9931037] siderophore-iron transmembrane transporter activity of FecA:TonB:ExbB:ExbD [periplasmic space]
category	transition
compartment	[Compartment:20798] cell outer membrane
created	[InstanceEdit:9931029] Stephan, Ralf, 2024-12-09
crossReference	[DatabaseIdentifier:12020761] Mondo:0005113
dbId	9931043
disease	[Disease:3134792] bacterial infectious disease
displayName	FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm
edited	[InstanceEdit:9948470] Stephan, Ralf, 2025-05-21
eventOf	[Pathway:R-HSA-9638482] Metal ion assimilation from the host - Homo sapiens
followingEvent	[Reaction:R-HSA-9931048] FecBCDE imports Fe3+-citrates to cytosol - Homo sapiens
input	[DefinedSet:R-ALL-9931069] Fe3+-citrates [extracellular region] [SimpleEntity:R-ALL-8858135] H+ [periplasmic space]
isChimeric	false
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:9931031] Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA [LiteratureReference:9931019] Citrate-dependent iron transport system in Escherichia coli K-12
maxDepth	1
modified	[InstanceEdit:9948469] Stephan, Ralf, 2025-05-21
name	FecA:TonB:ExbB:ExbD imports Fe3+-citrates to periplasm
output	[DefinedSet:R-ALL-9931051] Fe3+-citrates [periplasmic space] [SimpleEntity:R-ALL-70106] H+ [cytosol]
relatedSpecies	[Species:159879] Escherichia coli
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9931043
summation	[Summation:9931036] The FecA receptor imports Fe3+-citrates to the periplasm. Fe...

Referrals

(precedingEvent)	[Reaction:R-HSA-9931048] FecBCDE imports Fe3+-citrates to cytosol
(hasEvent)	[Pathway:R-HSA-9638482] Metal ion assimilation from the host

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